Imperial College London
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DrSeanBeevers

Faculty of Medicine, School of Public Health

Reader in Atmospheric modelling
 
 
 
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s.beevers

 
 
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Location

 

Norfolk PlaceSt Mary's Campus

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Summary

 

Publications

Citation

BibTex format

@article{Karamanos:2023:10.1371/journal.pone.0279719,
author = {Karamanos, A and Lu, Y and Mudway, IS and Ayis, S and Kelly, FJ and Beevers, SD and Dajnak, D and Fecht, D and Elia, C and Tandon, S and Webb, AJ and Grande, AJ and Molaodi, OR and Maynard, MJ and Cruickshank, JK and Harding, S},
doi = {10.1371/journal.pone.0279719},
journal = {PLoS One},
pages = {1--18},
title = {Associations between air pollutants and blood pressure in an ethnically diverse cohort of adolescents in London, England},
url = {http://dx.doi.org/10.1371/journal.pone.0279719},
volume = {18},
year = {2023}
}
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RIS format (EndNote, RefMan)

TY  - JOUR
AB  - Longitudinal evidence on the association between air pollution and blood pressure (BP) in adolescence is scarce. We explored this association in an ethnically diverse cohort of schoolchildren. Sex-stratified, linear random-effects modelling was used to examine how modelled residential exposure to annual average nitrogen dioxide (NO2), particulate matter (PM2.5, PM10) and ozone (O3), measures in μg/m3, associated with blood pressure. Estimates were based on 3,284 adolescents; 80% from ethnic minority groups, recruited from 51 schools, and followed up from 11–13 to 14–16 years old. Ethnic minorities were exposed to higher modelled annual average concentrations of pollution at residential postcode level than their White UK peers. A two-pollutant model (NO2 & PM2.5), adjusted for ethnicity, age, anthropometry, and pubertal status, highlighted associations with systolic, but not diastolic BP. A μg/m3 increase in NO2 was associated with a 0.30 mmHg (95% CI 0.18 to 0.40) decrease in systolic BP for girls and 0.19 mmHg (95% CI 0.07 to 0.31) decrease in systolic BP for boys. In contrast, a 1 μg/m3 increase in PM2.5 was associated with 1.34 mmHg (95% CI 0.85 to 1.82) increase in systolic BP for girls and 0.57 mmHg (95% CI 0.04 to 1.03) increase in systolic BP for boys. Associations did not vary by ethnicity, body size or socio-economic advantage. Associations were robust to adjustments for noise levels and lung function at 11–13 years. In summary, higher ambient levels of NO2 were associated with lower and PM2.5 with higher systolic BP across adolescence, with stronger associations for girls.
AU  - Karamanos,A
AU  - Lu,Y
AU  - Mudway,IS
AU  - Ayis,S
AU  - Kelly,FJ
AU  - Beevers,SD
AU  - Dajnak,D
AU  - Fecht,D
AU  - Elia,C
AU  - Tandon,S
AU  - Webb,AJ
AU  - Grande,AJ
AU  - Molaodi,OR
AU  - Maynard,MJ
AU  - Cruickshank,JK
AU  - Harding,S
DO  - 10.1371/journal.pone.0279719
EP  - 18
PY  - 2023///
SN  - 1932-6203
SP  - 1
TI  - Associations between air pollutants and blood pressure in an ethnically diverse cohort of adolescents in London, England
T2  - PLoS One
UR  - http://dx.doi.org/10.1371/journal.pone.0279719
UR  - https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0279719
UR  - http://hdl.handle.net/10044/1/102100
VL  - 18
ER  -
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