Publications
131 results found
Jaulent AM, Fahy AS, Knox SR, et al., 2007, A continuous assay for foot-and-mouth disease virus 3C protease activity, ANALYTICAL BIOCHEMISTRY, Vol: 368, Pages: 130-137, ISSN: 0003-2697
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- Citations: 14
Komatsu T, Nakagawa A, Zunszain PA, et al., 2007, Genetic engineering of the heme pocket in human serum albumin:: Modulation of O<sub>2</sub> binding of iron protoporphyrin IX by variation of distal amino acids, JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, Vol: 129, Pages: 11286-11295, ISSN: 0002-7863
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- Citations: 30
Monie TP, Perrin AJ, Birtley JR, et al., 2007, Structural insights into the transcriptional and translational roles of Ebp1, EMBO JOURNAL, Vol: 26, Pages: 3936-3944, ISSN: 0261-4189
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- Citations: 79
Roque-Rosell N, Curry S, Leatherbarrow RJ, 2007, Studies toward a new foot-and-mouth disease antiviral agent, ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, Vol: 233, Pages: 515-515, ISSN: 0065-7727
Curry S, 2007, Protein catalyzes hydrogen production from water, Industrial Bioprocessing, Vol: 29, ISSN: 1056-7194
Teruyuki Komatsu and Eishun Tsuchida of Waseda University, Stephen Curry of Imperial College London and others have constructed a complex of genetically modified human serum albumin and a zinc porphyrin compound that can capture light energy to split water into hydrogen and oxygen. This approach has potential for harnessing solar energy to produce hydrogen from water more cheaply. The researchers genetically engineered human serum albumin to make it more effective for use in this process.
Sweeney TR, Roque-Rosell N, Birtley JR, et al., 2007, Structural and mutagenic analysis of foot-and-mouth disease virus 3C protease reveals the role of the β-ribbon in proteolysis, JOURNAL OF VIROLOGY, Vol: 81, Pages: 115-124, ISSN: 0022-538X
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- Citations: 73
Curry S, Roque-Rosell N, Zunszain PA, et al., 2007, Foot-and-mouth disease virus 3C protease:: Recent structural and functional insights into an antiviral target, INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY, Vol: 39, Pages: 1-6, ISSN: 1357-2725
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- Citations: 40
Sweeney TR, Zunszain PA, Roque-Rosell N, et al., 2007, Structural and mutagenic analysis of foot-and-mouth disease virus 3C protease, Publisher: INT UNION CRYSTALLOGRAPHY, Pages: S26-S26, ISSN: 2053-2733
Ryan A, Ghuman J, Zunszain PA, et al., 2007, A Study of the Binding of Dansylated Amino Acids to Human Serum Albumin, Publisher: INT UNION CRYSTALLOGRAPHY, Pages: S19-S19, ISSN: 2053-2733
Komatsu T, Wang R-M, Zunszain PA, et al., 2006, Photosensitized reduction of water to hydrogen using human serum albumin complexed with zinc-protoporphyrin IX, JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, Vol: 128, Pages: 16297-16301, ISSN: 0002-7863
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- Citations: 82
Nayak A, Goodfellow IG, Woolaway KE, et al., 2006, Role of RNA structure and RNA binding activity of foot-and-mouth disease virus 3C protein in VPg uridylylation and virus replication, JOURNAL OF VIROLOGY, Vol: 80, Pages: 9865-9875, ISSN: 0022-538X
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- Citations: 63
Rideau AP, Gooding C, Simpson PJ, et al., 2006, A peptide motif in Raver1 mediates splicing repression by interaction with the PTB RRM2 domain, NATURE STRUCTURAL & MOLECULAR BIOLOGY, Vol: 13, Pages: 839-848, ISSN: 1545-9993
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- Citations: 78
Simard JR, Zunszain PA, Hamilton JA, et al., 2006, Location of high and low affinity fatty acid binding sites on human serum albumin revealed by NMR drug-competition analysis, JOURNAL OF MOLECULAR BIOLOGY, Vol: 361, Pages: 336-351, ISSN: 0022-2836
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- Citations: 285
Petoukhov MV, Monie TP, Allain FH-T, et al., 2006, Conformation of polypyrimidine tract binding protein in solution, STRUCTURE, Vol: 14, Pages: 1021-1027, ISSN: 0969-2126
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- Citations: 55
Curry S, Conte MR, 2006, A terminal affair:: 3′-end recognition by the human La protein, TRENDS IN BIOCHEMICAL SCIENCES, Vol: 31, Pages: 303-305, ISSN: 0968-0004
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- Citations: 14
Simard JR, Zunszain PA, Ha CE, et al., 2005, Locating high-affinity fatty acid-binding sites on albumin by x-ray crystallography and NMR spectroscopy, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, Vol: 102, Pages: 17958-17963, ISSN: 0027-8424
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- Citations: 227
Monie TP, Hernandez H, Robinson CV, et al., 2005, The polypyrimidine tract binding protein is a monomer, RNA, Vol: 11, Pages: 1803-1808, ISSN: 1355-8382
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- Citations: 34
Fasano M, Curry S, Terreno E, et al., 2005, The extraordinary ligand binding properties of human serum albumin, IUBMB LIFE, Vol: 57, Pages: 787-796, ISSN: 1521-6543
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- Citations: 801
Komatsu T, Ohmichi N, Nakagawa A, et al., 2005, O<sub>2</sub> and CO binding properties of artificial hemoproteins formed by complexing iron protoporphyrin IX with human serum albumin mutants, JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, Vol: 127, Pages: 15933-15942, ISSN: 0002-7863
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- Citations: 54
Ghuman J, Zunszain PA, Petitpas I, et al., 2005, Structural basis of the drug-binding specificity of human serum albumin, JOURNAL OF MOLECULAR BIOLOGY, Vol: 353, Pages: 38-52, ISSN: 0022-2836
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- Citations: 1483
Fry EE, Newman JWI, Curry S, et al., 2005, Structure of <i>Foot-and-mouth disease virus</i> serotype A10<sub>61</sub> alone and complexed with oligosaccharide receptor:: receptor conservation in the face of antigenic variation, JOURNAL OF GENERAL VIROLOGY, Vol: 86, Pages: 1909-1920, ISSN: 0022-1317
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- Citations: 90
Birtley JR, Curry S, 2005, Crystallization of foot-and-mouth disease virus 3C protease: surface mutagenesis and a novel crystal-optimization strategy, ACTA CRYSTALLOGRAPHICA SECTION D-STRUCTURAL BIOLOGY, Vol: 61, Pages: 646-650, ISSN: 2059-7983
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- Citations: 32
Birtley JR, Knox SR, Jaulent AM, et al., 2005, Crystal structure of foot-and-mouth disease virus 3C protease, JOURNAL OF BIOLOGICAL CHEMISTRY, Vol: 280, Pages: 11520-11527
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- Citations: 118
Ryan K, Schnatz P, Greene J, et al., 2005, Change in cesarean section rate as a reflection of the present malpractice crisis., Conn Med, Vol: 69, Pages: 139-141, ISSN: 0010-6178
OBJECTIVE: To examine the potential effect of the malpractice crisis on the cesarean section rates of practicing obstetricians. METHODS: We reviewed the medical records of primagravid women, from both clinic and private practice settings, having singleton deliveries at Hartford Hospital from 1994 to 2003. The records of cesarean sections due to fetal distress and cephalopelvic disproportion (CPD) were further analyzed for three different two-year periods; 1994-1995, 1999-2000, and 2002-2003. Cases with accepted indications for elective cesarean sections were excluded. These included breech position, HIV, herpes, preeclampsia, placenta previa, and abruptio placenta. RESULTS: The private cesarean rate in 1994-1995 was 15.6%, 1999-2000 15.7%, and in 2002-2003 24.8%, a 58% increase. This is a significant increase that was not equally seen in the clinic population during the same period. CONCLUSION: The private, primagravid cesarean section rate has increased significantly in the last two years. A concurrent rise in medical malpractice actions and malpractice insurance premiums, without other attributable explanations, suggests this may be a major factor.
Curry S, Birtley J, Knox S, et al., 2005, Structure, Mechanism and Specificity of FMDV 3C Protease, Publisher: INT UNION CRYSTALLOGRAPHY, Pages: C50-C50, ISSN: 2053-2733
Komatsu T, Ohmichi N, Zunszain PA, et al., 2004, Dioxygenation of human serum albumin having a prosthetic heme group in a tailor-made heme pocket, JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, Vol: 126, Pages: 14304-14305, ISSN: 0002-7863
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- Citations: 42
Simpson PJ, Monie TP, Szendröi A, et al., 2004, Structure and RNA interactions of the N-terminal RRM domains of PTB, STRUCTURE, Vol: 12, Pages: 1631-1643, ISSN: 0969-2126
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- Citations: 77
Sanfelice D, Babon J, Kelly G, et al., 2004, Letter to the Editor: Resonance assignment and secondary structure of the La motif, JOURNAL OF BIOMOLECULAR NMR, Vol: 29, Pages: 449-450, ISSN: 0925-2738
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- Citations: 4
Alfano C, Sanfelice D, Babon J, et al., 2004, Structural analysis of cooperative RNA binding by the La motif and central RRM domain of human La protein, NATURE STRUCTURAL & MOLECULAR BIOLOGY, Vol: 11, Pages: 323-329, ISSN: 1545-9993
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- Citations: 114
Simard JR, Zunszain P, Bhagavan NV, et al., 2004, Corellation of 13C-NMR peaks with specific fatty acid binding sites in human serum albumin, 48th Annual Meeting of the Biophysical Society, Publisher: BIOPHYSICAL SOCIETY, Pages: 75A-76A, ISSN: 0006-3495
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- Citations: 1
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