Publications
333 results found
Deb S, 2012, Reid C. & Deb S. (2012) Psychopharmacological approaches. In ‘Anxiety and depression in people with intellectual disabilities’ (Ed. R. Raghavan) Pavilion Press. Pp 105-123., Anxiety and depression in people with intellectual disabilities.
Chechlacz M, Rotshtein P, Hansen PC, et al., 2012, The Neural Underpinings of Simultanagnosia: Disconnecting the Visuospatial Attention Network, JOURNAL OF COGNITIVE NEUROSCIENCE, Vol: 24, Pages: 718-735, ISSN: 0898-929X
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- Citations: 45
Deb S, 2012, Berney T. & Deb S. (2012) Epilepsy in Learning Disability. In ‘Oxford Textbook of Epilepsy and Epileptic Seizures: Oxford Textbooks in Clinical Neurology’ (Eds. S. Shorvon, R. Guerrini, M. Cook & S. Lahtoo). Oxford University Press. Oxford, UK. Pp. 195-199., Oxford Textbook of Epilepsy and Epileptic Seizures: Oxford Textbooks in Clinical Neurology.
Deb S, 2012, Deb S. (2012) The use of medications for the management of problem behaviours in adults who have (learning) intellectual disabilities. In ‘lntellectualdisability.com’ St. George’s Medical School E-publication (updated module)., ‘lntellectualdisability.com’ St. George’s Medical School E-publication.
Njomboro P, Deb S, 2012, Poor dissociation of patient-evaluated apathy and depressive symptoms., Curr Gerontol Geriatr Res, Vol: 2012
Apathy has traditionally been conceptualised as part of depression. The appropriateness of this conceptualisation has now been questioned, with the realization that apathy constitutes a distinct neuropsychiatric condition, with separate rehabilitation and patient-care implications to depression. Research on the relationship between apathy and depression has, however, produced mixed results. One reason for this inconsistency may lie behind who does the apathy evaluation. In this study we investigated whether the relationship between apathy and depression would differ when apathy was evaluated by the patients or an informant. A total of 49 brain damaged patients were assessed on self- and informant-rated Apathy Evaluation Scales. The relationship between the apathy scores and depressive symptoms was then investigated. Patient-rated, and not informant-rated apathy significantly correlated with depression. We discuss the implication of these results on the relationship between the two neuropsychiatric conditions and also in relation to the utility of patient self-evaluations in apathy.
Chen VJ, Allen H, Deb S, et al., 2011, Role of emotion in shifting choice preference: a neuroscientific perspective., Frontiers in Psychology, Vol: 2, Pages: 300-300, ISSN: 1664-1078
What role(s) do emotions have in choice preference? Individuals’ choices depend on their memories and cognition but also on their current emotional state. Emotions can play a necessary functional role in decision-making, but in doing this, emotions can alter the stability of the process. The argument for a necessary functional role of emotions is supported by converging evidence from neuropsychological patients with impairments in either emotional responding or in decision-making, alongside human brain imaging. We also point out that functional brain imaging studies need to target brain areas responding to emotion in order to provide stronger evidence for emotion specifically modulating the process of decision-making to influence choice preference.
Salvador-Carulla L, Reed GM, Vaez-Azizi LM, et al., 2011, <i>Intellectual developmental disorders</i>: towards a new name, definition and framework for "mental retardation/intellectual disability" in ICD-11, WORLD PSYCHIATRY, Vol: 10, Pages: 175-180, ISSN: 1723-8617
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- Citations: 171
Unwin GL, Deb S, 2011, Efficacy of atypical antipsychotic medication in the management of behaviour problems in children with intellectual disabilities and borderline intelligence: A systematic review, RESEARCH IN DEVELOPMENTAL DISABILITIES, Vol: 32, Pages: 2121-2133, ISSN: 0891-4222
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- Citations: 38
Unwin G, Deb S, 2011, Family Caregiver Uplift and Burden: Associations With Aggressive Behavior in Adults With Intellectual Disability, JOURNAL OF MENTAL HEALTH RESEARCH IN INTELLECTUAL DISABILITIES, Vol: 4, Pages: 186-205, ISSN: 1931-5864
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- Citations: 21
Deb S, 2011, Rashid A., Unwin G., Mistry H. & Deb S. (2011) Service received by adults with intellectual disabilities and problem behaviour: a prospective observational study. Learning Disability Faculty Annual Residential Conference, Royal College of Psychiatrists, Bristol.
Deb S, 2011, Unwin G. & Deb S. (2011) A Survey of Service & Medication Use in Adults with Intellectual Disability Presenting With Aggression. Presented at the Royal College of Psychiatrists’ Faculty of Learning Disability Annual Residential Meeting, Bristol, UK.
Taylor A, Deb S, Unwin G, 2011, Scales for the identification of adults with attention deficit hyperactivity disorder (ADHD): A systematic review, RESEARCH IN DEVELOPMENTAL DISABILITIES, Vol: 32, Pages: 924-938, ISSN: 0891-4222
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- Citations: 79
Deb S, 2011, Deb S. (2011) Medication for the management of challenging behaviours in people with learning disabilities. In ‘Challenging behaviour and people with learning disabilities: a handbook’ (Eds. Steve Hardy and Theresa Joyce). Pavilion Publishing, Brighton, UK. Pp. 91-98., Challenging behaviour and people with learning disabilities: a handbook.
Deb S, 2011, Sadavoy J., Lanctôt K. L. & Deb S. (2011) Management of behavioural and psychological symptoms of dementia and acquired brain injury. In ‘Cambridge Textbook of Effective Treatments in Psychiatry’ (Eds. P. Tyrer & K. R. Silk), Cambridge University Press, Cambridge. (electronic version)., Cambridge Textbook of Effective Treatments in Psychiatry.
Deb S, 2011, Unwin G. L. & Deb S. (2011) Behavioural problems in adults with intellectual disabilities: medication management. In ‘101 Recipes for Audit in Psychiatry’ (Eds. C. Oakley, F. Coccia, N. Masson, I. McKinnon & M. Simmons). The Royal College of Psychiatrists Publication, London. Pp. 195-196. ISBN: 978-1-908020-01-7., 101 Recipes for Audit in Psychiatry.
Unwin G, Deb S, 2010, The use of medication to manage behaviour problems in adults with an intellectual disability: A national guideline, Advances in Mental Health and Intellectual Disabilities, Vol: 4, Pages: 4-11, ISSN: 2044-1282
This article describes a national guideline for the use of medication in the management of problem behaviours in adults with an intellectual disability. As problem behaviours in this group are common and medication is often prescribed ‘off licence’, it is important that a framework is established to direct this practice. The article details a guideline development project that is of importance because it is the only national guideline in the area. It also highlights important issues in clinical practice in the field, and addresses the current evidence base on the effectiveness of psychotropic medications in the management of problem behaviours. There is a lack of good research evidence to support use of medication for problem behaviours. Where medication is used for this purpose, it should be used with a clear rationale, following a thorough assessment of the individual, and carefully monitored, and withdrawal should always be considered. People should always be given information in a way that they understand, and they should be given choices about their treatment. © 2010, Emerald Group Publishing Limited
Deb S, Gomez A, 2010, A case series on the use of risperidone for the management of aggression in adults with intellectual disabilities, Advances in Mental Health and Intellectual Disabilities, Vol: 4, Pages: 39-44, ISSN: 2044-1282
Antipsychotic drugs are often used outside their licensed indication to manage aggression in adults with intellectual disabilities in the absence of a diagnosed psychiatric disorder. The current case series shows that antipsychotics could be effective, but they are often used with nondrug measures and sometimes cause sideeffects. Clinicians did not always carry out a thorough assessment followed by a formulation before prescribing medications, as recommended in the national and international guides (Deb et al, 2009; Unwin & Deb, 2010). It is also apparent that clinicians did not carry out tests to detect sideeffects of risperidone such as metabolic syndrome. Clinicians should use psychotropic medication for a minimum period of time and at the lowest possible dose, and should consider nondrug management of aggression at the outset and at a regular interval. © 2010, Emerald Group Publishing Limited
Deb S, 2010, Editorial Best practice in pharmacological interventions, Advances in Mental Health and Intellectual Disabilities, Vol: 4, Pages: 2-3, ISSN: 2044-1282
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- Citations: 2
Deb S, 2010, Unwin G., Teeluckdharry S. & Deb S. (2010) Triggers for aggression in adults with intellectual disabilities. Learning Disability Faculty Annual Residential Conference, Royal College of Psychiatrists, Leeds, UK.
Deb S, 2010, Unwin G. & Deb S. (2010) Carers of people with intellectual disabilities and aggressive behaviour: Uplift, Burden and Concerns. Learning Disability Faculty Annual Residential Conference, Royal College of Psychiatrists, Leeds, UK.
Deb S, 2010, Deb S. & Mungar N. (2010) Use of medication in challenging behaviour. In: 'Challenging behaviour: A training pack to develop good practice in working with people with learning disabilities whose behaviour is described as challenging' (Eds. S. Hardy & T. Joyce). OLM-Pavilion, Brighton, UK. Pp. 125-138 (ISBN: 978-1-84196-281-8)., Challenging behaviour: A training pack to develop good practice in working with people with learning disabilities whose behaviour is described as challenging.
Deb S, 2010, Deb S. (2010) Zdrowie psychiczne a padaczka u doroslyck osob niepelnosprawnych intelektualine. In ‘Zaburzenia Psychiczne i Zaburzenia Zachowania.' (Eds. N. Bouras & G. Holt). Elsevier, Warsaw, Poland, Pp. 261-276 (Polish version)., Zaburzenia Psychiczne i Zaburzenia Zachowania.
Kannabiran M, Deb S, 2010, Diseases of the nervous system II: Neurodegenerative diseases including dementias, Intellectual Disability and Ill Health: A Review of the Evidence, Pages: 203-213, ISBN: 9780521728898
Introduction: Neurodegenerative diseases (ND) are hereditary and sporadic conditions, characterised by progressive nervous system dysfunction (MeSH, 2009). They include Alzheimer's disease (AD) and other dementias, and conditions such as Huntington's disease, multiple sclerosis and motor neurone disease. It is now well known that a high proportion of people with Down syndrome (DS) develop AD at an early age (McCarron et al. (2005); also see Deb (2003) for a review). This chapter will review dementia in people with intellectual disability (ID) without DS, before discussing AD in people with DS in detail. Method: We used a broad search strategy using the National Library for Health (NLH) Advanced Search (AMED, BNI, EMBASE, HMIC, MEDLINE, PsycINFO, CINAHL and HEALTH BUSINESS ELITE) and Google Scholar. All relevant abstracts were read and relevant articles were inspected in more detail. Intellectual disability journals were hand searched for relevant papers. The following search terms were used: dementia, neurodegenerative, learning AND disability, intellectual AND disability, developmental AND disability, and mental AND retardation. The MeSH terms used were mental retardation and neurodegenerative disease. The first search was made in October 2008 and updated in December 2008.
Oliver-Africano P, Dickens S, Ahmed Z, et al., 2010, Overcoming the barriers experienced in conducting a medication trial in adults with aggressive challenging behaviour and intellectual disabilities, JOURNAL OF INTELLECTUAL DISABILITY RESEARCH, Vol: 54, Pages: 17-25, ISSN: 0964-2633
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- Citations: 31
Deb S, McHugh R, 2010, DEMENTIA AMONG PERSONS WITH DOWN SYNDROME, Publisher: ELSEVIER ACADEMIC PRESS INC, ISBN: 978-0-12-374477-7
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- Citations: 10
Chechlacz M, Rotshtein P, Bickerton W-L, et al., 2010, Separating neural correlates of allocentric and egocentric neglect: Distinct cortical sites and common white matter disconnections, COGNITIVE NEUROPSYCHOLOGY, Vol: 27, Pages: 277-303, ISSN: 0264-3294
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- Citations: 117
Deb S, 2009, Pharmacological Interventions, Intellectual Disability Psychiatry: A Practical Handbook, Pages: 203-222, ISBN: 9780470742518
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- Citations: 3
Deb S, Kwok H, Bertelli M, et al., 2009, International guide to prescribing psychotropic medication for the management of problem behaviours in adults with intellectual disabilities, WORLD PSYCHIATRY, Vol: 8, Pages: 181-186, ISSN: 1723-8617
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- Citations: 108
Deb S, 2009, Chechlacz M., Humphreys G. & Deb S. (2009) Mapping dysfunctional networks after brain injury: a case study of a patient with prosopagnosia and alexia. Journal of Neurology, Neurosurgery & Psychiatry, 80, 826., Journal of Neurology, Neurosurgery and Psychiatry, ISSN: 0022-3050
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