Publications
333 results found
Unwin GL, Deb S, 2008, Use of medication for the management of behavior problems among adults with intellectual disabilities: A clinicians' consensus survey, AMERICAN JOURNAL ON MENTAL RETARDATION, Vol: 113, Pages: 19-31, ISSN: 0895-8017
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- Citations: 22
Deb S, Sohanpal SK, Soni R, et al., 2007, The effectiveness of antipsychotic medication in the management of behaviour problems in adults with intellectual disabilities, JOURNAL OF INTELLECTUAL DISABILITY RESEARCH, Vol: 51, Pages: 766-777, ISSN: 0964-2633
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- Citations: 66
Sohanpal SK, Deb S, Thomas C, et al., 2007, The effectiveness of antidepressant medication in the management of behaviour problems in adults with intellectual disabilities:: a systematic review, JOURNAL OF INTELLECTUAL DISABILITY RESEARCH, Vol: 51, Pages: 750-765, ISSN: 0964-2633
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- Citations: 37
Deb S, Hare M, Prior L, 2007, Symptoms of dementia among adults with Down's syndrome: a qualitative study, JOURNAL OF INTELLECTUAL DISABILITY RESEARCH, Vol: 51, Pages: 726-739, ISSN: 0964-2633
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- Citations: 52
Deb S, Unwin GL, 2007, Psychotropic medication for behaviour problems in people with intellectual disability: a review of the current literature, CURRENT OPINION IN PSYCHIATRY, Vol: 20, Pages: 461-466, ISSN: 0951-7367
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- Citations: 53
Deb S, Saini STK, 2007, Levetiracetam for the treatment of epilepsy among adults with intellectual disabilities, JOURNAL OF INTELLECTUAL DISABILITY RESEARCH, Vol: 51, Pages: 564-565, ISSN: 0964-2633
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- Citations: 1
Deb S, Bryant E, Morris PG, et al., 2007, Development and psychometric properties of the Carer - Head Injury Neurobehavioral Assessment Scale (C-HINAS) and the Carer - Head Injury Participation Scale (C-HIPS): patient and family determined outcome scales., Neuropsychiatric Disease and Treatment, Vol: 3, Pages: 389-408, ISSN: 1176-6328
OBJECTIVE: Develop and assess the psychometric properties of the Carer - Head Injury Participation Scale (C-HIPS) and its biggest factor the Carer - Head Injury Neurobehavioral Assessment Scale (C-HINAS). Furthermore, the aim was to examine the inter-informant reliability by comparing the self reports of individuals with traumatic brain injury (TBI) with the carer reports on the C-HIPS and the C-HINAS. METHOD: Thirty-two TBI individuals and 27 carers took part in in-depth qualitative interviews exploring the consequences of the TBI. Interview transcripts were analysed and key themes and concepts were used to construct a 49-item and 58-item patient (Patient - Head Injury Participation Scale [P-HIPS]) and carer outcome measure (C-HIPS) respectively, of which 49 were parallel items and nine additional items were used to assess carer burden. Postal versions of the P-HIPS, C-HIPS, Mayo Portland Adaptability Inventory-3 (MPAI-3), and the Glasgow Outcome Scale-Extended (GOSE) were completed by a cohort of 113 TBI individuals and 80 carers. Data from a sub-group of 66 patient/carer pairs were used to compare inter-informant reliability between the P-HIPS and the C-HIPS, and the P-HINAS and the C-HINAS respectively. RESULTS: All individual 49 items of the C-HIPS and their total score showed good test-retest reliability (0.95) and internal consistency (0.95). Comparisons with the MPAI-3 and GOSE found a good correlation with the MPAI-3 (0.7) and a moderate negative correlation with the GOSE (-0.6). Factor analysis of these items extracted a 4-factor structure which represented the domains 'Emotion/Behavior' (C-HINAS), 'Independence/Community Living', 'Cognition', and 'Physical'. The C-HINAS showed good internal consistency (0.92), test-retest reliability (0.93), and concurrent validity with one MPAI subscale (0.7). Assessment of inter-informant reliability revealed good correspondence between the reports of the patients and the carers for both the C-HIPS (0.83) and the C-HINA
Deb S, Bryant E, Morris PG, et al., 2007, Development and psychometric properties of the Patient-Head Injury Participation Scale (P-HIPS) and the Patient-Head Injury Neurobehavioral Assessment Scale (P-HINAS): patient and family determined outcomes scales., Neuropsychiatr Dis Treat, Vol: 3, Pages: 373-388, ISSN: 1176-6328
OBJECTIVE: To develop a measure to assess post-acute outcome following from traumatic brain injury (TBI) with particular emphasis on the emotional and the behavioral outcome. The second objective was to assess the test-retest reliability, internal consistency, and factor structure of the newly developed patient version of the Head Injury Participation Scale (P-HIPS) and Patient-Head Injury Neurobehavioral Scale (P-HINAS). METHOD: Thirty-two TBI individuals and 27 carers took part in in-depth qualitative interviews exploring the consequences of the TBI. Interview transcripts were analyzed and key themes and concepts were used to construct the 49-item P-HIPS. A postal survey was then conducted on a cohort of 113 TBI patients to 'field test' the P-HIPS and the P-HINAS. RESULTS: All individual 49 items of the P-HIPS and their total score showed good test-retest reliability (0.93) and internal consistency (0.95). The P-HIPS showed a very good correlations with the Mayo Portland Adaptability Inventory-3 (MPAI-3) (0.87) and a moderate negative correlation with the Glasgow Outcome Scale-Extended (GOSE) (-0.51). Factor analysis extracted the following domains: 'Emotion/Behavior,' 'Independence/Community Living,' 'Cognition' and 'Physical'. The 'Emotion/Behavior' factor constituted the P-HINAS, which showed good internal consistency (0.93), test-retest reliability (0.91) and concurrent validity with MPAI subscale (0.82). CONCLUSIONS: Both the P-HIPS and the P-HINAS show strong psychometric properties. The qualitative methodology employed in the construction stage of the questionnaires provided good evidence of face and content validity.
Deb S, Hare M, Prior L, et al., 2007, Dementia screening questionnaire for individuals with intellectual disabilities, BRITISH JOURNAL OF PSYCHIATRY, Vol: 190, Pages: 440-444, ISSN: 0007-1250
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- Citations: 89
Deb S, 2007, Deb S. (2007) Epilepsy in people with mental retardation. In ‘Handbook of Mental Retardation and Developmental Disabilities’ (Eds. J. W. Jacobson & J. A. Maulick). Kluwer Academic Publishers, New York, USA, Pp. 81-96., Handbook of Mental Retardation and Developmental Disabilities.
Deb S, 2007, Deb S. (2007) The role of medication in the management of behaviour problems in people with learning disabilities. Advances in Mental Health and Learning Disabilities, 1(2), 26-31., Advances in Mental Health and Learning Disabilities.
Deb S, 2007, Deb S. & Srikanth R. (2007) Epilepsy and Intellectual Disability. The Royal College of Psychiatrists, UK, Online CPD Module. www.psychiatrycpd.org, The Royal College of Psychiatrists, UK, Online CPD Module.
Deb S, 2007, Deb S. & Unwin G. L. (2007) Guide to using psychotropic medication for the management of behaviour problems among adults with intellectual disability: technical document. University of Birmingham, Birmingham, UK. www.ld-medication.bham.ac.uk
Deb S, 2007, Mental health and epilepsy among adults with intellectual disabilities, Psychiatric and Behavioural Disorders in Intellectual and Developmental Disabilities, Pages: 238-251, ISBN: 9780521608251
Prevalence of epilepsy in people who have ID Epilepsy is a tendency of occurrence of transient recurrent abnormal electrical discharges in the brain, affecting one or more of the following brain functions: motor, sensory, cognitive, speech, behavioural, emotional and psychological. Around 0.5% of the general population has epilepsy (Chadwick, 1994). A much higher proportion of people who have intellectual disabilities (ID) have epilepsy. Although the exact figure is not known, the reported prevalence of lifetime epilepsy among people who have ID (IQ < 70) varies between 14% and 24% (Rutter et al., 1976; Forsgren et al., 1990; Goulden et al., 1991; McGrother et al., 1996; Deb, 1997a). The prevalence rate depends on the age of the person, severity and cause of ID, and the presence and absence of associated neurological conditions. For example, the cumulative incidence of epilepsy was reported to be 9%, 11%, 13% and 15% among people with ID at age 5, 10, 15 and 22 years respectively (Goulden et al., 1991). The rate of epilepsy increases with the severity of ID. Steffenburg et al. (1996) found among 378 children with ID between age 6 and 13, that 15% of those with mild ID, as opposed to 45% of those with severe ID, had epilepsy. Similarly Shepherd and Hosking (1989) found 7% of children with mild to moderate ID, and 67% of those with severe ID, had epilepsy.
Deb S, Burns J, 2007, Neuropsychiatric consequences of traumatic brain injury: A comparison between two age groups, BRAIN INJURY, Vol: 21, Pages: 301-307, ISSN: 0269-9052
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- Citations: 45
Deb S, 2006, Medication for behaviour problems associated with learning disabilities, Psychiatry, Vol: 5, Pages: 368-371, ISSN: 1476-1793
Many adults with learning disabilities show behaviour problems. It is imperative to find out the cause for and the consequences of the behaviour problems before deciding on an appropriate mode of management. Consider a non-medication management approach first. Sometimes it is necessary to use medication simultaneously with non-medication-based managements. Many medications, including antipsychotics, antidepressants, mood stabilizers such as lithium and some antiepileptic medications, opioid antagonists such as naltrexone and naloxene, benzodiazepines and buspirone, β-blockers, psychostimulants, and diet and vitamins, although not licensed for this use, have been shown to be effective in managing behaviour problems. However, the overall quality of evidence supporting their effectiveness is poor. Newer antipsychotics such as risperidone, olanzapine, amisulpiride, quetiapine and aripiprazole are preferred over the older generation of antipsychotics, although one has to be watchful about certain adverse effects such as weight gain, somnolence, cardiac abnormalities and metabolic effects such as glucose intolerance, hyperlipaedimia and hyperprolactaenimia. Overall, a lower dose of antipsychotics than is recommended in the British National Formulary for antipsychotic use is sufficient for the management of behaviour problems. Like antipsychotics, the newer generation of antidepressants such as SSRIs and SNRIs are preferred over the older generation of antidepressants. Once medication is prescribed, arrangements should be in place to monitor objectively the effectiveness and adverse effects. Medication treatment should be included within an overall person-centred planning or health action plan or care programme approach. As far as possible, the patients and the carers, and other relevant professionals, should be involved in the decision of prescribing medication. © 2006 Elsevier Ltd. All rights reserved.
Deb S, 2006, Deb S. & Saini S. (2006) Levetiracetam is an effective add-on treatment for adults with epilepsy and intellectual disabilities. 7th European Congress on Epileptology, European Epilepsy Association, Helsinki, Finland.
Deb S, 2006, Falope Z.F., Deb S., Powell T., Rickards H. & Njomboro P. (2006) Validity of HADS and BDI-II in outpatients with traumatic brain injury. International Conference on Brain Injury Rehabilitation, Hong Kong, China.
Deb S, 2006, Deb S. (2006) The use of psychotropic drugs in people with intellectual disabilities. In ‘The Psychiatry of Intellectual Disability’ (eds. A. Roy, M. Roy & D. Clarke), Radcliffe Publishing, Oxford, Pp. 155-162., The Psychiatry of Intellectual Disability.
Deb S, 2006, Falope Z. F., Deb S., Rickards H. & Powell T. (2006) The validity of Hospital Anxiety and Depression Scale and Beck’s Depression Inventory-II in acquired brain injury. Neurorehabilitation and Neural Repair, March, 20(1), 90., Neurorehabilitation and Neural Repair., ISSN: 1545-9683
Deb S, 2006, Deb S. (2006) Learning Disability (Mental Retardation), In ‘Shorter Oxford Textbook of Psychiatry’ (Eds. M. Gelder, P. Harrison & P. Cowen), Oxford University Press, Oxford Pp. 705-728 (book chapter 25)., Shorter Oxford Textbook of Psychiatry.
Unwin G, Deb S, 2006, Your Guide to Taking Medicine for Behaviour Problems, ISBN: 9780855370954
Morris PG, Prior L, Deb S, et al., 2005, Patients' views on outcome following head injury: a qualitative study., BMC Family Practice, Vol: 6, Pages: 1-6, ISSN: 1471-2296
BACKGROUND: Head injuries are a common occurrence, with continuing care in the years following injury being provided by primary care teams and a variety of speciality services. The literature on outcome currently reflects areas considered important by health-care professionals, though these may differ in some respects from the views of head injured individuals themselves. Our study aimed to identify aspects of outcome considered important by survivors of traumatic head injury. METHODS: Thirty-two individuals were interviewed, each of whom had suffered head injury between one and ten years previously from which they still had residual difficulties. Purposive sampling was used in order to ensure that views were represented from individuals of differing age, gender and level of disability. These interviews were fully transcribed and analysed qualitatively by a psychologist, a sociologist and a psychiatrist with regular meetings to discuss the coding. RESULTS: Aspects of outcome mentioned by head injury survivors which have received less attention previously included: specific difficulties with group conversations; changes in physical appearance due to scarring or weight change; a sense of loss for the life and sense of self that they had before the injury; and negative reactions of others, often due to lack of understanding of the consequences of injury amongst both family and general public. CONCLUSION: Some aspects of outcome viewed as important by survivors of head injury may be overlooked by health professionals. Consideration of these areas of outcome and the development of suitable interventions should help to improve functional outcome for patients.
Deb S, 2005, Falope Z. F., Deb S., Powell T., Rickards H. & Njomboro P. (2005) Preliminary study of Hospital Anxiety and Depression Scale (HADS) and Beck's Depression Inventory (BDI-II) in outpatients with acquired brain injury (ABI). National Conference on Brain Injury Rehabilitation, Leeds, UK.
Deb S, 2005, Unwin G. L. & Deb S. (2005) National guideline on the use of drugs for the treatment of behaviour disorders among adults who have intellectual disabilities. Royal College of Psychiatrists Learning Disability Faculty Annual National Residential Conference, Jersey.
Deb S, 2005, Deb S. & Iyer A. (2005) Clinical interviews. In, ‘Mood disorders in people with mental retardation’ (Ed. P. Sturmey), Pp 159-173, NADD Press, NY, USA (book chapter)., Mood disorders in people with mental retardation.
DEB S, FRASER W, 2004, THE USE OF PSYCHOTROPIC MEDICATION IN PEOPLE WITH LEARNING-DISABILITY - TOWARDS RATIONAL PRESCRIBING, HUMAN PSYCHOPHARMACOLOGY-CLINICAL AND EXPERIMENTAL, Vol: 9, Pages: 259-272, ISSN: 0885-6222
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- Citations: 52
DEB S, HUNTER D, 2004, THE EFFECT OF ANTICONVULSANT MEDICATION ON THE PSYCHOPATHOLOGY OF ADULTS WITH A MENTAL HANDICAP AND EPILEPSY, HUMAN PSYCHOPHARMACOLOGY-CLINICAL AND EXPERIMENTAL, Vol: 7, Pages: 129-134, ISSN: 0885-6222
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- Citations: 5
Deb S, 2004, Unwin G. L. & Deb S. (2004) The role of systematic reviews in intellectual disability research. 7th Congress of the International Association for Scientific Studies in Intellectual Disabilities (IASSID), Montpellier, France.
Deb S, 2004, Lenotre L. & Deb S. (2004) A systematic review of the evidence on the use of drugs for the management of behaviour disorders in adults who have an intellectual disability and autism. 7th Congress of the International Association for Scientific Studies in Intellectual Disabilities (IASSID), Montpellier, France.
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