Imperial College London
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ProfessorSimoneDi Giovanni

Faculty of Medicine, Department of Brain Sciences

James W Harnett Chair in Restorative Neuroscience
 
 
 
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Contact

 

+44 (0)20 7594 3178s.di-giovanni

 
 
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Location

 

E505Burlington DanesHammersmith Campus

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Summary

 

Publications

Citation

BibTex format

@article{Erharhaghen:2011:10.1159/000330376,
author = {Erharhaghen, J and Bartz, M and Di, Giovanni S and Melms, A and Haarmeier, T and Sieverding, L},
doi = {10.1159/000330376},
journal = {Case Rep Neurol},
pages = {160--164},
title = {An unusual location of deep venous thrombosis associated with ischemic stroke and persistent foramen ovale.},
url = {http://dx.doi.org/10.1159/000330376},
volume = {3},
year = {2011}
}
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RIS format (EndNote, RefMan)

TY  - JOUR
AB  - Up to 40% of ischemic strokes have no known cause (cryptogenic). The prevalence of persistent foramen ovale (PFO) amongst patients with cryptogenic stroke (CS) is twice as high as that of the normal population, therefore suggesting a causal relationship between the two entities. However, PFO by itself is not sufficient to cause stroke, as an embolic source is needed. This source is often unknown, making the causal relationship between CS and PFO hard to demonstrate. The most frequent, although still seldom, identifiable cause of embolism in an otherwise cryptogenic stroke associated with PFO is a deep venous thrombosis (DVT) of the lower extremities. Here, we present a unique case of brachiocephalic venous DVT associated with PFO and ischemic stroke in a young patient. As the search for DVT in patients with PFO and stroke is often limited to the lower extremities, this case may suggest that an unspecified number of DVTs are overlooked. Our report lends support to paradoxical embolism as a mechanism of stroke in patients with PFO and does, at least in selected cases, suggest a more detailed search for DVT beyond the lower extremities.
AU  - Erharhaghen,J
AU  - Bartz,M
AU  - Di,Giovanni S
AU  - Melms,A
AU  - Haarmeier,T
AU  - Sieverding,L
DO  - 10.1159/000330376
EP  - 164
PY  - 2011///
SP  - 160
TI  - An unusual location of deep venous thrombosis associated with ischemic stroke and persistent foramen ovale.
T2  - Case Rep Neurol
UR  - http://dx.doi.org/10.1159/000330376
UR  - https://www.ncbi.nlm.nih.gov/pubmed/21829401
VL  - 3
ER  -
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