Imperial College London
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ProfessorStephenDurham

Faculty of Medicine, National Heart & Lung Institute

Professor of Allergy and Respiratory
 
 
 
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Contact

 

+44 (0)20 7351 8024s.durham

 
 
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Location

 

Fulham RoadRoyal Brompton Campus

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Summary

 

Publications

Citation

BibTex format

@article{Bousquet:2019:10.1111/all.13805,
author = {Bousquet, J and Pfaar, O and Togias, A and Schünemann, HJ and Ansotegui, I and Papadopoulos, NG and Tsiligianni, I and Agache, I and Anto, JM and Bachert, C and Bedbrook, A and Bergmann, KC and Bosnic-Anticevich, S and Bosse, I and Brozek, J and Calderon, M and Canonica, GW and Caraballo, L and Cardona, V and Casale, T and Cecchi, L and Chu, DK and Costa, E and Cruz, AA and Czarlewski, W and Durham, SR and Du, Toit G and Dykewicz, M and Ebisawa, M and Fauquert, JL and Fernandez-Rivas, M and Fokkens, WJ and Fonseca, J and Fontaine, JF and van, Wijk RG and Haahtela, T and Halken, S and Hellings, PW and Ierodiakonou, D and Iinuma, T and Ivancevich, JC and Jacobsen, L and Jutel, M and Kaidashev, I and Khaitov, M and Kalayci, O and Kleine, Tebbe J and Klimek, L and Kowalski, ML and Kuna, P and Kvedariene, V and La, Grutta S and Larenas-Linemann, D and Lau, S and Laune, D and Le, L and Carlsen, KL and Lourenço, O and Malling, HJ and Marien, G and Menditto, E and Mercier, G and Mullol, J and },
doi = {10.1111/all.13805},
journal = {Allergy},
title = {2019 ARIA Care pathways for allergen immunotherapy.},
url = {http://dx.doi.org/10.1111/all.13805},
year = {2019}
}
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RIS format (EndNote, RefMan)

TY  - JOUR
AB  - Allergen immunotherapy (AIT) is a proven therapeutic option for the treatment of allergic rhinitis and/or asthma. Many guidelines or national practice guidelines have been produced but the evidence-based method varies, many are complex and none propose care pathways. This paper reviews care pathways for AIT using strict criteria and provides simple recommendations that can be used by all stakeholders including health professionals. The decision to prescribe AIT for the patient should be individualized and based on the relevance of the allergens, the persistence of symptoms despite appropriate medications according to guidelines as well as on the availability of good-quality and efficacious extracts. Allergen extracts cannot be regarded as generics. Immunotherapy is selected by specialists for stratified patients. There are no currently available validated biomarkers that can predict AIT success. In adolescents and adults, AIT should be reserved for patients with moderate/severe rhinitis or for those with moderate asthma who, despite appropriate pharmacotherapy and adherence, continue to exhibit exacerbations that appear to be related to allergen exposure, except in some specific cases. Immunotherapy may be even more advantageous in patients with multimorbidity. In children, AIT may prevent asthma onset in patients with rhinitis. mHealth tools are promising for the stratification and follow up of patients. This article is protected by copyright. All rights reserved.
AU  - Bousquet,J
AU  - Pfaar,O
AU  - Togias,A
AU  - Schünemann,HJ
AU  - Ansotegui,I
AU  - Papadopoulos,NG
AU  - Tsiligianni,I
AU  - Agache,I
AU  - Anto,JM
AU  - Bachert,C
AU  - Bedbrook,A
AU  - Bergmann,KC
AU  - Bosnic-Anticevich,S
AU  - Bosse,I
AU  - Brozek,J
AU  - Calderon,M
AU  - Canonica,GW
AU  - Caraballo,L
AU  - Cardona,V
AU  - Casale,T
AU  - Cecchi,L
AU  - Chu,DK
AU  - Costa,E
AU  - Cruz,AA
AU  - Czarlewski,W
AU  - Durham,SR
AU  - Du,Toit G
AU  - Dykewicz,M
AU  - Ebisawa,M
AU  - Fauquert,JL
AU  - Fernandez-Rivas,M
AU  - Fokkens,WJ
AU  - Fonseca,J
AU  - Fontaine,JF
AU  - van,Wijk RG
AU  - Haahtela,T
AU  - Halken,S
AU  - Hellings,PW
AU  - Ierodiakonou,D
AU  - Iinuma,T
AU  - Ivancevich,JC
AU  - Jacobsen,L
AU  - Jutel,M
AU  - Kaidashev,I
AU  - Khaitov,M
AU  - Kalayci,O
AU  - Kleine,Tebbe J
AU  - Klimek,L
AU  - Kowalski,ML
AU  - Kuna,P
AU  - Kvedariene,V
AU  - La,Grutta S
AU  - Larenas-Linemann,D
AU  - Lau,S
AU  - Laune,D
AU  - Le,L
AU  - Carlsen,KL
AU  - Lourenço,O
AU  - Malling,HJ
AU  - Marien,G
AU  - Menditto,E
AU  - Mercier,G
AU  - Mullol,J
AU  - Muraro,A
AU  - O'Hehir,R
AU  - Okamoto,Y
AU  - Pajno,GB
AU  - Park,HS
AU  - Panzner,P
AU  - Passalacqua,G
AU  - Pham-Thi,N
AU  - Roberts,G
AU  - Rolland,C
AU  - Rosario,N
AU  - Ryan,D
AU  - Samolinski,B
AU  - Sanchez-Borges,M
AU  - Scadding,G
AU  - Shamji,MH
AU  - Sheikh,A
AU  - Sturm,GJ
AU  - Todo,Bom A
AU  - Toppila-Salmi,S
AU  - Valentin-Rostan,M
AU  - Valiulis,A
AU  - Valovirta,E
AU  - Ventura,MT
AU  - Wahn,U
AU  - Walker,S
AU  - Wallace,D
AU  - Waserman,S
AU  - Yorgancioglu,A
AU  - Zuberbier,T
AU  - ARIA,Working Group
DO  - 10.1111/all.13805
PY  - 2019///
TI  - 2019 ARIA Care pathways for allergen immunotherapy.
T2  - Allergy
UR  - http://dx.doi.org/10.1111/all.13805
UR  - https://www.ncbi.nlm.nih.gov/pubmed/30955224
ER  -
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