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@article{Loxley:2020:10.1098/rsob.200218,
author = {Loxley, GM and Hooks, DO and Antonopoulos, A and Dell, A and Haslam, SM and Linklater, WL and Hurst, JL and Beynon, RJ},
doi = {10.1098/rsob.200218},
journal = {Open Biology},
title = {Vulpeculin: a novel and abundant lipocalin in the urine of the common brushtail possum, Trichosurus vulpecula},
url = {http://dx.doi.org/10.1098/rsob.200218},
volume = {10},
year = {2020}
}

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TY  - JOUR
AB  - Lipocalins are a family of secreted proteins. They are capable of binding small lipophilic compounds and have been extensively studied for their role in chemosignalling in rodent urine. Urine of the common brushtail possum (Trichosurus vulpecula) contains a prominent glycoprotein of 20 kDa, expressed in both sexes. We have isolated this protein and determined its primary sequence by mass spectrometry, including the use of metabolic labelling to resolve the leucine/isoleucine isobaric ambiguity. The protein sequence was identified as a lipocalin, and phylogenetic analysis grouped the protein with other marsupial lipocalin sequences in a phylogenetic clade distinct from established cross-species lipocalin sub-families. The pattern of expression in possum urine and the similarity in sequence and structure to other lipocalins suggests this protein may have a role in brushtail possum chemosignalling.
AU  - Loxley,GM
AU  - Hooks,DO
AU  - Antonopoulos,A
AU  - Dell,A
AU  - Haslam,SM
AU  - Linklater,WL
AU  - Hurst,JL
AU  - Beynon,RJ
DO  - 10.1098/rsob.200218
PY  - 2020///
SN  - 2046-2441
TI  - Vulpeculin: a novel and abundant lipocalin in the urine of the common brushtail possum, Trichosurus vulpecula
T2  - Open Biology
UR  - http://dx.doi.org/10.1098/rsob.200218
UR  - https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000578418900001&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=a2bf6146997ec60c407a63945d4e92bb
UR  - https://royalsocietypublishing.org/doi/10.1098/rsob.200218
UR  - http://hdl.handle.net/10044/1/107487
VL  - 10
ER  -

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