Prof Steve Matthews

Faculty of Natural Sciences, Department of Life Sciences

Professor of Chemical and Structural Biology

Contact

+44 (0)20 7594 5315s.j.matthews Website

Location

602Sir Ernst Chain BuildingSouth Kensington Campus

Summary

Selected Publications

Journal Articles

Chorev DS, Baker LA, Wu D, et al.Chorev DS, Baker LA, Wu D, Beilsten-Edmands V, Rouse SL, Zeev-Ben-Mordehai T, Jiko C, Samsudin F, Gerle C, Khalid S, Stewart AG, Matthews SJ, Gruenewald K, Robinson CV close, 2018, Protein assemblies ejected directly from native membranes yield complexes for mass spectrometry, Science, Vol:362, ISSN:0036-8075, Pages:829-+

Grundy GJ, Polo LM, Zeng Z, et al.Grundy GJ, Polo LM, Zeng Z, Rulten SL, Hoch NC, Paomephan P, Xu Y, Sweet SM, Thorne AW, Oliver AW, Matthews SJ, Pearl LH, Caldecott KW close, 2016, PARP3 is a sensor of nicked nucleosomes and monoribosylates histone H2B(Glu2), Nature Communications, Vol:7, ISSN:2041-1723

Taylor JD, Hawthorne WJ, Lo J, et al.Taylor JD, Hawthorne WJ, Lo J, Dear A, Jain N, Meisl G, Andreasen M, Fletcher C, Koch M, Darvill N, Scull N, Escalera-Maurer A, Sefer L, Wenman R, Lambert S, Jean J, Xu Y, Turner B, Kazarian SG, Chapman MR, Bubeck D, de Simone A, Knowles TPJ, Matthews SJ close, 2016, Electrostatically-guided inhibition of Curli amyloid nucleation by the CsgC-like family of chaperones, Scientific Reports, Vol:6, ISSN:2045-2322

Wong CT, Xu Y, Gupta A, et al.Wong CT, Xu Y, Gupta A, Garnett JA, Matthews SJ, Hare SA close, 2015, Structural analysis of haemoglobin binding by HpuA from the Neisseriaceae family, Nature Communications, Vol:6, ISSN:2041-1723

Miliara X, Garnett JA, Tatsuta T, et al.Miliara X, Garnett JA, Tatsuta T, Abid Ali F, Baldie H, Perez-Dorado I, Simpson P, Yague E, Langer T, Matthews S close, 2015, Structural insight into the TRIAP1/PRELI-like domain family of mitochondrial phospholipid transfer complexes, EMBO Reports, Vol:16, ISSN:1469-221X, Pages:824-835

Evans ML, Chorell E, Taylor JD, et al.Evans ML, Chorell E, Taylor JD, Aden J, Gotheson A, Li F, Koch M, Sefer L, Matthews SJ, Wittung-Stafshede P, Almqvist F, Chapman MR close, 2015, The Bacterial Curli System Possesses a Potent and Selective Inhibitor of Amyloid Formation, Molecular Cell, Vol:57, ISSN:1097-2765, Pages:445-455

Young JC, Clements A, Lang AE, et al.Young JC, Clements A, Lang AE, Garnett JA, Munera D, Arbeloa A, Pearson J, Hartland EL, Matthews SJ, Mousnier A, Barry DJ, Way M, Schlosser A, Aktories K, Frankel G close, 2014, The Escherichia coli effector EspJ blocks Src kinase activity via amidation and ADP ribosylation, Nature Communications, Vol:5, ISSN:2041-1723

Xu Y, Plechanovova A, Simpson P, et al.Xu Y, Plechanovova A, Simpson P, Marchant J, Leidecker O, Kraatz S, Hay RT, Matthews SJ close, 2014, Structural insight into SUMO chain recognition and manipulation by the ubiquitin ligase RNF4, Nature Communications, Vol:5, ISSN:2041-1723

Cehovin A, Simpson PJ, McDowell MA, et al.Cehovin A, Simpson PJ, McDowell MA, Brown DR, Noschese R, Pallett M, Brady J, Baldwin GS, Lea SM, Matthews SJ, Pelicic V close, 2013, Specific DNA recognition mediated by a type IV pilin, Proceedings of the National Academy of Sciences of the United States of America, Vol:110, ISSN:0027-8424, Pages:3065-3070

Hughes S, Elustondo F, Di Fonzo A, et al.Hughes S, Elustondo F, Di Fonzo A, Leroux FG, Wong AC, Snijders AP, Matthews SJ, Cherepanov P close, 2012, Crystal structure of human CDC7 kinase in complex with its activator DBF4, Nature Structural & Molecular Biology, Vol:19, ISSN:1545-9993, Pages:1101-+

James E, Liu M, Sheppard C, et al.James E, Liu M, Sheppard C, Mekler V, Camara B, Liu B, Simpson P, Cota E, Severinov K, Matthews S, Wigneshweraraj S close, 2012, Structural and Mechanistic Basis for the Inhibition of Escherichia coli RNA Polymerase by T7 Gp2, Molecular Cell, Vol:47, ISSN:1097-2765, Pages:755-766

Garnett JA, Martinez-Santos VI, Saldana Z, et al.Garnett JA, Martinez-Santos VI, Saldana Z, Pape T, Hawthorne W, Chan J, Simpson PJ, Cota E, Puente JL, Giron JA, Matthews S close, 2012, Structural insights into the biogenesis and biofilm formation by the Escherichia coli common pilus, Proceedings of the National Academy of Sciences of the United States of America, Vol:109, ISSN:0027-8424, Pages:3950-3955

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