Publications

BibTex format

@article{Coultas:2021:10.2147/JEP.S255211,
author = {Coultas, JA and Cafferkey, J and Mallia, P and Johnston, SL},
doi = {10.2147/JEP.S255211},
journal = {J Exp Pharmacol},
pages = {645--659},
title = {Experimental Antiviral Therapeutic Studies for Human Rhinovirus Infections.},
url = {http://dx.doi.org/10.2147/JEP.S255211},
volume = {13},
year = {2021}
}

Download

RIS format (EndNote, RefMan)

TY  - JOUR
AB  - Rhinovirus infection is common and usually causes mild, self-limiting upper respiratory tract symptoms. Rhinoviruses can cause exacerbation of chronic respiratory diseases, such as asthma or chronic obstructive pulmonary disease, leading to a significant burden of morbidity and mortality. There has been a great deal of progress in efforts to understand the immunological basis of rhinovirus infection. However, despite a number of in vitro and in vivo attempts, there have been no effective treatments developed. This review article summarises the up to date virological and immunological understanding of these infections. We discuss the challenges researchers face, and key solutions, in their work to investigate potential therapies including in vivo rhinovirus challenge studies. Finally, we explore past and present experimental therapeutic strategies employed in the treatment of rhinovirus infections and highlight promising areas of future work.
AU  - Coultas,JA
AU  - Cafferkey,J
AU  - Mallia,P
AU  - Johnston,SL
DO  - 10.2147/JEP.S255211
EP  - 659
PY  - 2021///
SN  - 1179-1454
SP  - 645
TI  - Experimental Antiviral Therapeutic Studies for Human Rhinovirus Infections.
T2  - J Exp Pharmacol
UR  - http://dx.doi.org/10.2147/JEP.S255211
UR  - https://www.ncbi.nlm.nih.gov/pubmed/34276229
VL  - 13
ER  -

Download

ProfessorSebastianJohnston

Contact

Assistant

Location

Summary

Citation

BibTex format

RIS format (EndNote, RefMan)