Publications
380 results found
Gabrienko AA, Lai CH, Kazarian SG, 2014, In Situ Chemical Imaging of Asphaltene Precipitation from Crude Oil Induced by <i>n</i>-Heptane, ENERGY & FUELS, Vol: 28, Pages: 964-971, ISSN: 0887-0624
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- Citations: 28
Actis P, Tokar S, Clausmeyer J, et al., 2014, Electrochemical nanoprobes for single-cell analysis, ACS Nano, Vol: 8, Pages: 875-884, ISSN: 1936-0851
The measurement of key molecules in individual cells with minimal disruption to the biological milieu is the next frontier in single-cell analyses. Nanoscale devices are ideal analytical tools because of their small size and their potential for high spatial and temporal resolution recordings. Here, we report the fabrication of disk-shaped carbon nanoelectrodes whose radius can be precisely tuned within the range 5–200 nm. The functionalization of the nanoelectrode with platinum allowed the monitoring of oxygen consumption outside and inside a brain slice. Furthermore, we show that nanoelectrodes of this type can be used to impale individual cells to perform electrochemical measurements within the cell with minimal disruption to cell function. These nanoelectrodes can be fabricated combined with scanning ion conductance microscopy probes, which should allow high resolution electrochemical mapping of species on or in living cells.
Silverwood IP, Keyworth CW, Brown NJ, et al., 2014, An Attenuated Total Reflection Fourier Transform Infrared (ATR FT-IR) Spectroscopic Study of Gas Adsorption on Colloidal Stearate-Capped ZnO Catalyst Substrate, APPLIED SPECTROSCOPY, Vol: 68, Pages: 88-94, ISSN: 0003-7028
Ishikawa D, Shinzawa H, Genkawa T, et al., 2014, Recent Progress of Near-Infrared (NIR) Imaging -Development of Novel Instruments and Their Applicability for Practical Situations-, ANALYTICAL SCIENCES, Vol: 30, Pages: 143-150, ISSN: 0910-6340
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- Citations: 22
Benetti C, Kazarian SG, Alves MAV, et al., 2014, Attenuated total reflection Fourier transform infrared (ATR-FTIR) spectroscopic analysis of regenerated bone, Conference on Photonic Therapeutics and Diagnostics X, Publisher: SPIE-INT SOC OPTICAL ENGINEERING, ISSN: 0277-786X
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- Citations: 4
Glassford SE, Byrne B, Kazarian SG, 2013, Recent applications of ATR FTIR spectroscopy and imaging to proteins, BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS, Vol: 1834, Pages: 2849-2858, ISSN: 1570-9639
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- Citations: 186
Ishikawa D, Nishii T, Mizuno F, et al., 2013, Potential of a Newly Developed High-Speed Near-Infrared (NIR) Camera (Compovision) in Polymer Industrial Analyses: Monitoring Crystallinity and Crystal Evolution of Poly lactic Acid (PLA) and Concentration of PLA in PLA/Poly-(R)-3-Hydroxybutyrate (PHB) Blends, APPLIED SPECTROSCOPY, Vol: 67, Pages: 1441-1446, ISSN: 0003-7028
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- Citations: 24
Fernandez-Francos X, Kazarian SG, Ramis X, et al., 2013, Simultaneous Monitoring of Curing Shrinkage and Degree of Cure of Thermosets by Attenuated Total Reflection Fourier Transform Infrared (ATR FT-IR) Spectroscopy, APPLIED SPECTROSCOPY, Vol: 67, Pages: 1427-1436, ISSN: 0003-7028
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- Citations: 24
Ishikawa D, Murayama K, Awa K, et al., 2013, Application of a newly developed portable NIR imaging device to monitor the dissolution process of tablets, ANALYTICAL AND BIOANALYTICAL CHEMISTRY, Vol: 405, Pages: 9401-9409, ISSN: 1618-2642
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- Citations: 33
Kimber JA, Kazarian SG, Stepanek F, 2013, DEM simulation of drug release from structurally heterogeneous swelling tablets, POWDER TECHNOLOGY, Vol: 248, Pages: 68-76, ISSN: 0032-5910
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- Citations: 15
Dougan JA, Kazarian SG, 2013, Fourier transform infrared spectroscopic imaging of live cells, Spectroscopy Europe, Vol: 25, Pages: 6-12, ISSN: 0966-0941
FT-IR imaging is made possible by coupling a spectrometer with a focal plane array (FPA) detector. Instead of a single spectrum being produced, the FPA detector allows thousands of spectra to be concurrently recorded. The exact value is dependent upon a number of parameters such as the refractive indices of both materials, the wavelength of light and the angle of incidence. Nevertheless, the small depth of penetration results in a small effective pathlength in practice, this means that samples can be analyzed in the presence of a highly absorbing species such as water without loss of spectral integrity in the regions of interest. The best spatial resolution is obtained using micro ATR FT-IR imaging. This approach has recently been applied to study the crystallization of proteins.
Kazarian SG, Ewing AV, 2013, Applications of Fourier transform infrared spectroscopic imaging to tablet dissolution and drug release, EXPERT OPINION ON DRUG DELIVERY, Vol: 10, Pages: 1207-1221, ISSN: 1742-5247
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- Citations: 57
Kharintsev SS, Rogov AM, Kazarian SG, 2013, Nanopatterning and tuning of optical taper antenna apex for tip-enhanced Raman scattering performance, REVIEW OF SCIENTIFIC INSTRUMENTS, Vol: 84, ISSN: 0034-6748
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- Citations: 17
Wray PS, Clarke GS, Kazarian SG, 2013, Dissolution of tablet-in-tablet formulations studied with ATR-FTIR spectroscopic imaging, EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES, Vol: 48, Pages: 748-757, ISSN: 0928-0987
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- Citations: 26
Kimber JA, Kazarian SG, Stepanek F, 2013, Formulation design space analysis for drug release from swelling polymer tablets, POWDER TECHNOLOGY, Vol: 236, Pages: 179-187, ISSN: 0032-5910
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- Citations: 19
Chan KLA, Kazarian SG, 2013, Correcting the Effect of Refraction and Dispersion of Light in FT-IR Spectroscopic Imaging in Transmission through Thick Infrared Windows, ANALYTICAL CHEMISTRY, Vol: 85, Pages: 1029-1036, ISSN: 0003-2700
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- Citations: 40
Lee K-Y, Qian H, Tay FH, et al., 2013, Bacterial cellulose as source for activated nanosized carbon for electric double layer capacitors, JOURNAL OF MATERIALS SCIENCE, Vol: 48, Pages: 367-376, ISSN: 0022-2461
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- Citations: 44
Chan KLA, Kazarian SG, 2013, Aberration-free FTIR spectroscopic imaging of live cells in microfluidic devices, ANALYST, Vol: 138, Pages: 4040-4047, ISSN: 0003-2654
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- Citations: 50
Kazarian SG, Chan KLA, 2013, ATR-FTIR spectroscopic imaging: recent advances and applications to biological systems, ANALYST, Vol: 138, Pages: 1940-1951, ISSN: 0003-2654
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- Citations: 280
Hasell T, Armstrong JA, Jelfs KE, et al., 2013, High-pressure carbon dioxide uptake for porous organic cages: comparison of spectroscopic and manometric measurement techniques, CHEMICAL COMMUNICATIONS, Vol: 49, Pages: 9410-9412, ISSN: 1359-7345
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- Citations: 40
Glassford SE, Govada L, Chayen NE, et al., 2012, Micro ATR FTIR imaging of hanging drop protein crystallisation, VIBRATIONAL SPECTROSCOPY, Vol: 63, Pages: 492-498, ISSN: 0924-2031
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- Citations: 20
Bailey MJ, Bright NJ, Croxton RS, et al., 2012, Chemical Characterization of Latent Fingerprints by Matrix-Assisted Laser Desorption Ionization, Time-of-Flight Secondary Ion Mass Spectrometry, Mega Electron Volt Secondary Mass Spectrometry, Gas Chromatography/Mass Spectrometry, X-ray Photoelectron Spectroscopy, and Attenuated Total Reflection Fourier Transform Infrared Spectroscopic Imaging: An Intercomparison, ANALYTICAL CHEMISTRY, Vol: 84, Pages: 8514-8523, ISSN: 0003-2700
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- Citations: 77
Chan KLA, Kazarian SG, 2012, Label-Free Chemical Detection in Microfabricated Devices Using FT-IR Spectroscopic Imaging, SPECTROSCOPY, Vol: 27, Pages: 22-+, ISSN: 0887-6703
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- Citations: 8
Chan KLA, Kazarian SG, 2012, FT-IR Spectroscopic Imaging of Reactions in Multiphase Flow in Microfluidic Channels, ANALYTICAL CHEMISTRY, Vol: 84, Pages: 4052-4056, ISSN: 0003-2700
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- Citations: 58
Glassford S, Chan KLA, Byrne B, et al., 2012, Chemical Imaging of Protein Adsorption and Crystallization on a Wettability Gradient Surface, LANGMUIR, Vol: 28, Pages: 3174-3179, ISSN: 0743-7463
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- Citations: 28
Kimber JA, Kazarian SG, Stepanek F, 2012, Modelling of pharmaceutical tablet swelling and dissolution using discrete element method, CHEMICAL ENGINEERING SCIENCE, Vol: 69, Pages: 394-403, ISSN: 0009-2509
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- Citations: 26
Kimber JA, Kazarian SG, Stepanek F, 2011, A fast algorithm for mass transfer on an unstructured grid formed by DEM particles, POWDER TECHNOLOGY, Vol: 214, Pages: 415-422, ISSN: 0032-5910
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- Citations: 4
Wray PS, Clarke GS, Kazarian SG, 2011, Application of FTIR Spectroscopic Imaging to Study the Effects of Modifying the pH Microenvironment on the Dissolution of Ibuprofen from HPMC Matrices, JOURNAL OF PHARMACEUTICAL SCIENCES, Vol: 100, Pages: 4745-4755, ISSN: 0022-3549
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- Citations: 34
Hameed N, Guo Q, Tay FH, et al., 2011, Blends of cellulose and poly(3-hydroxybutyrate-co-3-hydroxyvalerate) prepared from the ionic liquid 1-butyl-3-methylimidazolium chloride, CARBOHYDRATE POLYMERS, Vol: 86, Pages: 94-104, ISSN: 0144-8617
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- Citations: 48
Kimber JA, Kazarian SG, Stepanek F, 2011, Microstructure-based mathematical modelling and spectroscopic imaging of tablet dissolution, COMPUTERS & CHEMICAL ENGINEERING, Vol: 35, Pages: 1328-1339, ISSN: 0098-1354
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- Citations: 39
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