Imperial College London
Alternate

Professor Sergei Kazarian

Faculty of Engineering, Department of Chemical Engineering

Professor of Physical Chemistry
 
 
 
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Contact

 

+44 (0)20 7594 5574s.kazarian Website

 
 
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Assistant

 

Mrs Sarah Payne +44 (0)20 7594 5567

 
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Location

 

440Bone BuildingSouth Kensington Campus

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Summary

 

Publications

Citation

BibTex format

@article{Paraskevaidi:2021:10.1080/05704928.2021.1946076,
author = {Paraskevaidi, M and Matthew, BJ and Holly, BJ and Hugh, BJ and Thulya, CPV and Loren, C and StJohn, C and Peter, G and Callum, G and Sergei, KG and Kamila, K and Maria, K and Kassio, LMG and Pierre, M-HL and Evangelos, P and Savithri, P and John, AA and Alexandra, S and Marfran, S and Josep, S-S and Gunjan, T and Michael, W and Bayden, W},
doi = {10.1080/05704928.2021.1946076},
journal = {Applied Spectroscopy Reviews},
pages = {804--868},
title = {Clinical applications of infrared and Raman spectroscopy in the fields of cancer and infectious diseases},
url = {http://dx.doi.org/10.1080/05704928.2021.1946076},
volume = {56},
year = {2021}
}
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RIS format (EndNote, RefMan)

TY  - JOUR
AB  - Analytical technologies that can improve disease diagnosis are highly sought after. Current screening/diagnostic tests for several diseases are limited by their moderate diagnostic performance, invasiveness, costly and laborious methodologies or the need for multiple tests before a definitive diagnosis. Spectroscopic techniques, including infrared (IR) and Raman, have attracted great interest in the medical field, with applications expanding from early disease detection to monitoring and real-time diagnosis. This review highlights applications of IR and Raman spectroscopy, with a focus on cancer and infectious diseases since 2015, and underscores the diverse sample types that can be analyzed, such as biofluids, cells and tissues. Studies involving more than 25 participants per group (disease and control group; if no control group >25 in disease group) were considered eligible, to retain the clinical focus of the paper. Following literature searches, we identified 94 spectroscopic studies on different cancers and 30 studies on infectious diseases. The review suggests that such technologies have the potential to develop into an objective, inexpensive, point-of-care test or facilitate disease diagnosis and monitoring. Up-to-date considerations for the implementation of spectroscopic techniques into a clinical setting, health economics and successful applications of vibrational spectroscopic tests in the clinical arena are also discussed.
AU  - Paraskevaidi,M
AU  - Matthew,BJ
AU  - Holly,BJ
AU  - Hugh,BJ
AU  - Thulya,CPV
AU  - Loren,C
AU  - StJohn,C
AU  - Peter,G
AU  - Callum,G
AU  - Sergei,KG
AU  - Kamila,K
AU  - Maria,K
AU  - Kassio,LMG
AU  - Pierre,M-HL
AU  - Evangelos,P
AU  - Savithri,P
AU  - John,AA
AU  - Alexandra,S
AU  - Marfran,S
AU  - Josep,S-S
AU  - Gunjan,T
AU  - Michael,W
AU  - Bayden,W
DO  - 10.1080/05704928.2021.1946076
EP  - 868
PY  - 2021///
SN  - 0570-4928
SP  - 804
TI  - Clinical applications of infrared and Raman spectroscopy in the fields of cancer and infectious diseases
T2  - Applied Spectroscopy Reviews
UR  - http://dx.doi.org/10.1080/05704928.2021.1946076
UR  - http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000705357800001&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=1ba7043ffcc86c417c072aa74d649202
UR  - https://www.tandfonline.com/doi/full/10.1080/05704928.2021.1946076
UR  - http://hdl.handle.net/10044/1/92372
VL  - 56
ER  -
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