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@article{Pavagada:2019:10.1039/c9cc05607f,
author = {Pavagada, S and Channon, RB and Chang, JYH and Kim, SH and MacIntyre, D and Bennett, PR and Terzidou, V and Ladame, S},
doi = {10.1039/c9cc05607f},
journal = {Chemical Communications},
pages = {12451--12454},
title = {Oligonucleotide-templated lateral flow assays for amplification-free sensing of circulating microRNAs},
url = {http://dx.doi.org/10.1039/c9cc05607f},
volume = {55},
year = {2019}
}

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TY  - JOUR
AB  - Herein we demonstrate the first example of oligonucleotide-templated reaction (OTR) performed on paper, using lateral flow to capture and concentrate specific nucleic acid biomarkers on a test line. Quantitative analysis, using a low-cost benchtop fluorescence reader showed very high specificity down to the single nucleotide level and proved sensitive enough for amplification-free, on-chip, detection of endogenous concentrations of miR-150-5p, a recently identified predictive blood biomarker for preterm birth.
AU  - Pavagada,S
AU  - Channon,RB
AU  - Chang,JYH
AU  - Kim,SH
AU  - MacIntyre,D
AU  - Bennett,PR
AU  - Terzidou,V
AU  - Ladame,S
DO  - 10.1039/c9cc05607f
EP  - 12454
PY  - 2019///
SN  - 1359-7345
SP  - 12451
TI  - Oligonucleotide-templated lateral flow assays for amplification-free sensing of circulating microRNAs
T2  - Chemical Communications
UR  - http://dx.doi.org/10.1039/c9cc05607f
UR  - http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000490492700033&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=1ba7043ffcc86c417c072aa74d649202
UR  - https://pubs.rsc.org/en/content/articlelanding/2019/CC/C9CC05607F
UR  - http://hdl.handle.net/10044/1/74645
VL  - 55
ER  -

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