Imperial College London
Portrait Picture

Dr Shivani Misra

Faculty of Medicine, Department of Metabolism, Digestion and Reproduction

Clinical Senior Lecturer in Diabetes and Endocrinology
 
 
 
//

Contact

 

s.misra

 
 
//

Location

 

Commonwealth BuildingHammersmith Campus

//

Summary

 

Publications

Citation

BibTex format

@article{Eng:2022:10.1111/dom.14692,
author = {Eng, PC and Distaso, W and Durreshahwar, H and Shaikhali, Y and Narendranathan, D and Cassin-Scott, R and Misra, S and Hill, NE and Tharakan, G and Oliver, NS and Tan, TM and Izzi-Engbeaya, C and Salem, V},
doi = {10.1111/dom.14692},
journal = {Diabetes, Obesity and Metabolism: a journal of pharmacology and therapeutics},
pages = {1385--1389},
title = {The benefit of dexamethasone in patients with COVID-19 infection is preserved in patients with diabetes.},
url = {http://dx.doi.org/10.1111/dom.14692},
volume = {24},
year = {2022}
}
Download

RIS format (EndNote, RefMan)

TY  - JOUR
AB  - Dexamethasone significantly  reduces mortality1  and is  now  standard  treatment  for  patients   with   COVID-19   who   require   supplemental   oxygen and/or   mechanical   ventilation.  However,  supraphysiological  doses  of  glucocorticoids  may  exacerbate  dysglycaemia and precipitate hyperglycaemic complications, particularly in those with or  at  risk  of  Type  2  diabetes2.    The  RECOVERY  trial1  reported  a  low  incidence  of  hyperglycaemic  complications  (2/1996,  0.1%),  although  the  real-world  incidence  is  likely to be much higher3.  Type 2 diabetes itself increases the risk of severe   COVID-194,    and hyperglycaemia independently predicts poor outcomes5.  We investigated the possibility  that  patients  with  diabetes  may  derive less  survival  benefit  from  steroid  therapy in the setting of severe COVID-19 infection
AU  - Eng,PC
AU  - Distaso,W
AU  - Durreshahwar,H
AU  - Shaikhali,Y
AU  - Narendranathan,D
AU  - Cassin-Scott,R
AU  - Misra,S
AU  - Hill,NE
AU  - Tharakan,G
AU  - Oliver,NS
AU  - Tan,TM
AU  - Izzi-Engbeaya,C
AU  - Salem,V
DO  - 10.1111/dom.14692
EP  - 1389
PY  - 2022///
SN  - 1462-8902
SP  - 1385
TI  - The benefit of dexamethasone in patients with COVID-19 infection is preserved in patients with diabetes.
T2  - Diabetes, Obesity and Metabolism: a journal of pharmacology and therapeutics
UR  - http://dx.doi.org/10.1111/dom.14692
UR  - https://www.ncbi.nlm.nih.gov/pubmed/35293117
UR  - https://dom-pubs.onlinelibrary.wiley.com/doi/10.1111/dom.14692
UR  - http://hdl.handle.net/10044/1/96015
VL  - 24
ER  -
Download