Imperial College London
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DrSoniaNielles-Vallespin

Faculty of Medicine, National Heart & Lung Institute

Senior Lecturer in Physics of CMR
 
 
 
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s.nielles-vallespin

 
 
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Guy Scadding BuildingRoyal Brompton Campus

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Summary

 

Publications

Citation

BibTex format

@article{Gorodezky:2018:10.1002/mrm.27051,
author = {Gorodezky, M and Scott, AD and Ferreira, PF and Nielles-Vallespin, S and Pennell, DJ and Firmin, DN},
doi = {10.1002/mrm.27051},
journal = {Magnetic Resonance in Medicine},
pages = {648--654},
title = {Diffusion tensor cardiovascular magnetic resonance with a spiral trajectory: An in vivo comparison of echo planar and spiral stimulated echo sequences},
url = {http://dx.doi.org/10.1002/mrm.27051},
volume = {80},
year = {2018}
}
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RIS format (EndNote, RefMan)

TY  - JOUR
AB  - PURPOSE: Diffusion tensor cardiovascular MR (DT-CMR) using stimulated echo acquisition mode (STEAM) with echo-planar-imaging (EPI) readouts is a low signal-to-noise-ratio (SNR) technique and therefore typically has a low spatial resolution. Spiral trajectories are more efficient than EPI, and could increase the SNR. The purpose of this study was to compare the performance of a novel STEAM spiral DT-CMR sequence with an equivalent established EPI technique. METHODS: A STEAM DT-CMR sequence was implemented with a spiral readout and a reduced field of view. An in vivo comparison of DT-CMR parameters and data quality between EPI and spiral was performed in 11 healthy volunteers imaged in peak systole and diastasis at 3 T. The SNR was compared in a phantom and in vivo. RESULTS: There was a greater than 49% increase in the SNR in vivo and in the phantom measurements (in vivo septum, systole: SNREPI  = 8.0 ± 2.2, SNRspiral  = 12.0 ± 2.7; diastasis: SNREPI  = 8.1 ± 1.6, SNRspiral  = 12.0 ± 3.7). There were no significant differences in helix angle gradient (HAG) (systole: HAGEPI  = -0.79 ± 0.07 °/%; HAGspiral  = -0.74 ± 0.16 °/%; P = 0.11; diastasis: HAGEPI  = -0.63 ± 0.05 °/%; HAGspiral  = -0.56 ± 0.14 °/%; P = 0.20), mean diffusivity (MD) in systole (MDEPI  = 0.99 ± 0.06 × 10-3 mm2 /s, MDspiral  = 1.00 ± 0.09 × 10-3 mm2 /s, P = 0.23) and secondary eigenvector angulation (E2A) (systole: E2AEPI  = 61 ± 10 °; E2Aspiral  = 63 ± 10 °; P&thi
AU  - Gorodezky,M
AU  - Scott,AD
AU  - Ferreira,PF
AU  - Nielles-Vallespin,S
AU  - Pennell,DJ
AU  - Firmin,DN
DO  - 10.1002/mrm.27051
EP  - 654
PY  - 2018///
SN  - 0740-3194
SP  - 648
TI  - Diffusion tensor cardiovascular magnetic resonance with a spiral trajectory: An in vivo comparison of echo planar and spiral stimulated echo sequences
T2  - Magnetic Resonance in Medicine
UR  - http://dx.doi.org/10.1002/mrm.27051
UR  - http://hdl.handle.net/10044/1/55583
VL  - 80
ER  -
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