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@article{Benson:2021:10.1097/SLA.0000000000004722,
author = {Benson, R and Nandhra, S and Shalhoub, J},
doi = {10.1097/SLA.0000000000004722},
journal = {Annals of Surgery},
pages = {630--635},
title = {Outcomes of vascular and endovascular interventions performed during the COronaVIrus Disease 2019 (COVID-19) pandemic: The Vascular and Endovascular Research Network (VERN) COvid-19 Vascular sERvice (COVER) Tier 2 study},
url = {http://dx.doi.org/10.1097/SLA.0000000000004722},
volume = {273},
year = {2021}
}

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TY  - JOUR
AB  - Objective: The aim of the COVER Study is to identify global outcomes and decision making for vascular procedures during the pandemic.Background data: During its initial peak, there were many reports of delays to vital surgery and the release of several guidelines advising later thresholds for vascular surgical intervention for key conditions.Methods: An international multi-centre observational study of outcomes following open and endovascular interventions.Results: In an analysis of 1,103 vascular intervention (57 centres in 19 countries), 71.6% were elective or scheduled procedures. Mean age was 67 ± 14 years (75.6% male). Suspected or confirmed COVID-19 infection was documented in 4.0%. Overall, in-hospital mortality was 11.0%. (aortic interventions mortality 15.2% [23/151], amputations 12.1% [28/232], carotid interventions 10.7% [11/103], lower limb revascularisations 9.8% [51/521]). Chronic obstructive pulmonary disease (Odds ratio [OR] 2.02, 95% CI 1.30-3.15) and active lower respiratory tract infection due to any cause (OR 24.94, 95% CI 12.57-241.70) ware associated with mortality, whereas elective or scheduled cases were lower risk (OR 0.4, 95% CI 0.22-0.73 and 0.60, 95% CI 0.45-0.98 respectively. After adjustment, antiplatelet (Odds Ratio [OR] 0.503, 95% Confidence Interval [CI]:0.273 - 0.928) and oral anticoagulation (OR 0.411, 95% CI: 0.205 - 0.824) were linked to reduced risk of in-hospital mortality.Conclusions: Mortality following vascular interventions during this period was unexpectedly high. Suspected or confirmed COVID-19 cases were uncommon. Therefore an alternative cause e.g. recommendations for delayed surgery, should be considered. The vascular community must anticipate longer term implications for survival.Copyright © 2020 Wolters Kluwer Health, Inc. All rights reserved.
AU  - Benson,R
AU  - Nandhra,S
AU  - Shalhoub,J
DO  - 10.1097/SLA.0000000000004722
EP  - 635
PY  - 2021///
SN  - 0003-4932
SP  - 630
TI  - Outcomes of vascular and endovascular interventions performed during the COronaVIrus Disease 2019 (COVID-19) pandemic: The Vascular and Endovascular Research Network (VERN) COvid-19 Vascular sERvice (COVER) Tier 2 study
T2  - Annals of Surgery
UR  - http://dx.doi.org/10.1097/SLA.0000000000004722
UR  - https://journals.lww.com/annalsofsurgery/Fulltext/2021/04000/Outcomes_of_Vascular_and_Endovascular.4.aspx
UR  - http://hdl.handle.net/10044/1/85202
VL  - 273
ER  -

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