Publications
259 results found
Padley S, Mackenzie L, 2001, Special Investigations in Vascular Surgery: Doppler/Duplex Scanning, Publisher: [Oxford, Oxfordshire]: Medicine …
Koh DM, Bell JRG, Burkill GJC, et al., 2001, Mycobacterial infections: Still a millennium bug–the imaging features of Mycobacterial infections, Clinical radiology
Murray D, Padley S, 2000, Postoperative Chest Radiology in Cardiothoracic Surgery, Publisher: [Oxford, Oxfordshire]: Medicine …
King LJ, Padley SPG, Wotherspoon AC, 2000, Pulmonary MALT lymphoma: imaging findings in 24 cases, European radiology
HUGHES M, McCALL JM, NOTT D, et al., 2000, Treatment of iatrogenic femoral artery pseudoaneurysms using ultrasound-guided injection of thrombin, Clinical radiology
Davies CW, Tasker AD, Padley SP, et al., 2000, Air trapping in sarcoidosis on computed tomography: correlation with lung function., Clinical …
Ng CS, Desai SR, Rubens MB, et al., 1999, Visual quantitation and observer variation of signs of small airways disease at inspiratory and expiratory CT, Pages: 279-285, ISSN: 0883-5993
Areas of decreased pulmonary attenuation representing small airways disease can be identified on computed tomography (CT). The objective was to quantify differences between inspiratory and expiratory CT for the detection of signs of small airways disease by four observers. Observer variation and the superiority of a fine versus a coarse grading system were also evaluated. Inspiratory and expiratory CT scans of 106 patients with conditions characterized by small airways disease and 19 healthy individuals were assessed by four observers. The extent of decreased attenuation was scored on a fine scale to the nearest 5% and also semiquantitatively on a coarser 5-point scale. Decreased attenuation was more extensive on expiratory CT (median, 6.7%; 0-76.7%) than on inspiratory CT (median, 3.8%; 0-81.7%). The fine scoring system had unacceptable interobserver variation (coefficient of variation, 80% for inspiratory CT, 70% for expiratory CT). The semiquantitative system had acceptable interobserver agreement (inspiratory CT kw = 0.64; expiratory CT, kw = 0.69) and good intra-observer agreement (inspiratory CT, kw = 0.80; expiratory CT, kw = 0.64). The major CT sign of small airways disease is more confidently quantified on expiratory CT. A fine scoring system is associated with unacceptable observer variation, and a coarse semiquantitative system is more suitable for quantitative studies of small airways disease. © 1999 Lippincott Williams and Wilkins, Inc.
Ng CS, Wells AU, Padley SPG, 1999, A CT sign of chronic pulmonary arterial hypertension: The ratio of main pulmonary artery to aortic diameter, Pages: 270-278, ISSN: 0883-5993
The aim of this study was to determine whether the ratio of the diameters of the main pulmonary artery and of the ascending aorta (rPA), as assessed on computed tomography (CT), is predictive of pulmonary arterial hypertension (PAH). We undertook a retrospective review of 50 patients with a wide range of pulmonary and cardiovascular diseases, who had undergone both chest CT and pulmonary arterial pressure measurements at right heart catheterization. Two independent observers made measurements of the diameter of the main pulmonary artery and of the ascending aorta on a single defined CT section. Body surface area (BSA, n = 48), pulmonary arteriolar resistance (n = 39), total lung capacity (n = 40), and aortic pressures (n = 50) were also recorded. rPA and pulmonary arterial diameter (dPA) were positively related to mean pulmonary artery pressure (Rs = 0.74, p < 0.0005 for both analyses). For patients younger than 50 years of age, mean pulmonary artery pressure correlated more strongly with rPA than dPA (Rs = 0.77, p < 0.00005, compared with Rs = 0.59, p < 0.005); and vice versa for patients older than 50 years of age (Rs = 0.63, p < 0.005, compared with Rs = 0.75, p < 0.00005). Using a mean pulmonary artery pressure greater than 20 mm Hg as indicative of PAH and a value of rPA > 1, the sensitivity, specificity, and positive and negative predictive values for determining PAH were 70% (26/37), 92% (12/13), 96% (26/27), and 52% (12/23), respectively. On multivariate analysis, rPA was positively related to mean pulmonary artery pressure (p < 0.0005), and negatively related to age (p < 0.0005), but was not related to BSA. By contrast, dPA showed some dependency on BSA (p < 0.0005), as well as on mean pulmonary arterial pressure. In patients younger than 50 years of age, we have found a strong correlation between rPA and mean pulmonary artery pressure in a heterogeneous study population, and this relationship is independent of BSA and sex. The pr
Jordan SJ, Galasco G, Padley S, 1999, ARDS following lobectomy: a unilateral phenomenon?, THORAX- …
Fotheringham T, Chabat F, Hansell DM, et al., 1999, A comparison of methods for enhancing the detection of areas of decreased attenuation on CT caused by airways disease, Journal of Computer Assisted Tomography, Vol: 23, Pages: 385-389
Ng CS, Desai SR, Rubens MB, 1999, Visual quantitation and observer variation of signs of small airways disease at inspiratory and expiratory CT, Journal of thoracic …
Ng CS, Wells AU, Padley SPG, 1999, A CT sign of chronic pulmonary arterial hypertension: the ratio of main pulmonary artery to aortic diameter, Journal of thoracic imaging
Burkill GJC, Bell JRG, Padley SPG, 1999, Survey on the use of pulmonary scintigraphy, spiral CT and conventional pulmonary angiography for suspected pulmonary embolism in the British Isles, Clinical radiology
Zambanini A, Padley S, Cox A, et al., 1999, Achilles tendonitis: an unusual complication of amlodipine therapy., Journal of human …
Padley SPG, King LJ, 1999, Computed tomography of the thorax in HIV disease, European radiology
King LJ, Padley SP, Nicholson AG, 1998, Primary pulmonary lymphoma of malt origin: Imaging findings in 22 patients, RADIOLOGY, Vol: 209P, Pages: 376-376, ISSN: 0033-8419
Hartman TE, Swensen SJ, Hansell DM, et al., 1998, Non-specific interstitial pneumonitis variable appearance on high resolution CT, RADIOLOGY, Vol: 209P, Pages: 178-178, ISSN: 0033-8419
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Hannon FB, Easterbrook PJ, Padley S, 1998, Bronchopulmonary Kaposi s sarcoma in 106 HIV 1 infected patients, … journal of STD & …
Padley SPG, Rubens MB, 1998, Chest trauma; the postoperative chest; intensive care; radiation
Teare JP, Daly CA, Rodgers C, et al., 1997, Pancreatic abnormalities and AIDS related sclerosing cholangitis, Genitourinary Medicine, Vol: 73, Pages: 271-273, ISSN: 0266-4348
Objectives: Biliary tract abnormalities are well recognised in AIDS, most frequently related to opportunistic infection with Cryptosporidium, Microsporidium, and cytomegalovirus. We noted a high frequency of pancreatic abnormalities associated with biliary tract disease. To define these further we reviewed the clinical and radiological features in these patients. Methods: Notes and radiographs were available from two centres for 83 HIV positive patients who had undergone endoscopic retrograde cholangiopancreatography for the investigation of cholestatic liver function tests or abdominal pain. Results: 56 patients had AIDS related sclerosing cholangitis (ARSC); 86% of these patients had epigastric or right upper quadrant pain and 52% had hepatomegaly. Of the patients with ARSC, 10 had papillary stenosis alone, 11 had intra- and extrahepatic sclerosing cholangitis alone, and 35 had a combination of the two. Ampullary biopsies performed in 24 patients confirmed an opportunistic infection in 16. In 15 patients, intraluminal polyps were noted on the cholangiogram. Pancreatograms were available in 34 of the 45 patients with papillary stenosis, in which 29 (81%) had associated pancreatic duct dilatation, often with associated features of chronic pancreatitis. In the remaining 27 patients, final diagnoses included drug induced liver disease, acalculous cholecystitis, gall bladder empyema, chronic B virus hepatitis, and alcoholic liver disease. Conclusion. Pancreatic abnormalities are commonly seen with ARSC and may be responsible for some of the pain not relieved by biliary sphincterotomy. The most frequent radiographic biliary abnormality is papillary stenosis combined with ductal sclerosis.
Worthy SA, Müller NL, Hartman TE, et al., 1997, Mosaic attenuation pattern on thin-section CT scans of the lung: Differentiation among infiltrative lung, airway, and vascular diseases as a cause, Radiology, Vol: 205, Pages: 465-470, ISSN: 0033-8419
PURPOSE: To determine whether infiltrative lung, airway, or vascular disease can be differentiated as the cause of mosaic attenuation on thin- section computed tomographic (CT) scans of the lung. MATERIALS AND METHODS: Thin-section CT scans were reviewed in 70 patients examined at three institutions. A mosaic attenuation pattern and pathologic or clinical proof of a specific type of disease were demonstrated. Causes of the mosaic pattern included infiltrative lung disease (n = 37), airway disease (n = 22), and vascular disease (n = 11). Thin-section CT findings were assessed independently by two observers blinded to clinical findings. RESULTS: The type of disease was identified correctly at CT in 58 (83%) of 70 patients by observer 1 and 57 (81%) of 70 patients by observer 2. Infiltrative lung disease was diagnosed correctly by both observers in 34 (92%) of 37 cases. Observer 1 identified 21 (95%) of 22 cases of airway disease and three (27%) of 11 cases of vascular disease. Observer 2 identified 19 (86%) of 22 cases of airway disease and four (36%) of 11 cases of vascular disease. CONCLUSION: Infiltrative lung disease and airway disease may be differentiated reliably as the cause of mosaic attenuation on lung CT scans, whereas vascular disease is often misinterpreted as infiltrative lung disease or airway disease.
Sansom H, Seddon B, Padley SPG, 1997, Clinical utility of abdominal CT scanning in patients with HIV disease, Brain and Language, Vol: 52, Pages: 698-703, ISSN: 0093-934X
Aim: To evaluate the yield of abdominal computed tomography (CT) in patients with human immunodeficiency virus (HIV) infection and to assess the influence of CT scanning on patient management and diagnosis. Method: A retrospective analysis of 216 abdominal CT scans, performed on 156 patients (147 men, nine women; age range 22-57 years), between March 1992 and October 1994 was undertaken. Clinical information, including the indication for performing the scan and the eventual diagnosis, was obtained from the case notes and the contribution of CT scanning to patient management assessed. Results: Indications for CT fell into five main groups: investigation of pyrexia of unknown origin (PUO) (n = 82), staging and response to treatment of previously diagnosed neoplasms (n = 46), investigation of abdominal pain (n = 20), CT undertaken to clarify the results of other imaging investigations (n = 20) and miscellaneous indications (n = 48). An eventual diagnosis thought to account for the clinical presentation was made in 150 cases (68%), reflecting the high level of underlying pathology. CT contributed to patient management in a large proportion of cases (62%), but only led directly to a diagnosis in a minority (12%). Conclusion: With the exception of patients presenting with PUO, abdominal CT remains an important investigation in the management of patients with HIV infection. In patients presenting with PUO a thorough infection screen should be undertaken prior to CT scanning. Whilst frequently contributing to patient management, CT rarely leads directly to a diagnosis. © 1997 The Royal College of Radiologists.
Daly CA, Nott DM, Padley SPG, 1997, Aortoduodenal fistula: appearances on computed tomography, Australian and New Zealand …
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