Imperial College London

Dr Sofia Pappa MD, Ph.D

Faculty of MedicineDepartment of Brain Sciences

Honorary Senior Lecturer







Charing Cross HospitalCharing Cross Campus





Dr Sofia Pappa is a Senior Lecturer at the Division of Psychiatry, Imperial College London and a Specialty Lead in Mental Health for the National Institute for Health Research (NIHR,UK). She also works as a Consultant Psychiatrist and Mood & Psychosis Research Lead at West London NHS Trust.

She has dual training in Neurology and Psychiatry and was awarded a European scholarship for the completion of her PhD. She subsequently obtained a fellowship for postdoctoral research at the Institute of Psychiatry, Kings College London, evaluating the neuromotor dysfunction in early psychosis.

Her main clinical and research interests include neuropsychopharmacology and novel treatments in the management of affective and psychotic disorders. She has also a keen interest in the interface between physical and mental health, neuropsychiatry (particularly in movement and sleep disorders)  and patient involvement.  

Dr Pappa has received a number of awards and grants and has acted as Principal Investigator for several clinical trials. She has published in high impact journals and regularly reviews manuscripts for top ranked journals and NIHR  applications.

She has significant experience in teaching including in her role as Imperial Medical School Tutor and Associate Clinical Professor in Psychiatry, RUSM Medical School (Florida, US) and in clinical management, having served as Clinical Lead for Adult Mental Health Services in the past.



Pappa S, Barnett J, Mason K, 2023, A 10-year observational study of the use, acceptability and effectiveness of long-acting paliperidone Palmitate: implications for clinical decision making, Cns Drugs, Vol:37, ISSN:1172-7047, Pages:107-116

Chapman N, Browning M, Baghurst D, et al., 2022, Setting national research priorities for difficult-to-treat depression in the UK between 2021-2026., J Glob Health, Vol:12

Taylor D, Chithiramohan R, Grewal J, et al., 2022, Dopamine partial agonists: a discrete class of antipsychotics, International Journal of Psychiatry in Clinical Practice, ISSN:1365-1501

Pappa S, Kalniunas A, Sharma H, et al., 2022, Efficacy and safety of cariprazine augmentation in patients treated with clozapine: a pilot study, Therapeutic Advances in Psychopharmacology, Vol:12, ISSN:2045-1253, Pages:1-7


Asimakos A, Spetsioti S, Vogiatzis I, et al., 2022, Rehabilitation facilitates the natural recovery of symptoms, mental health and quality of life outcomes post COVID-19, EUROPEAN RESPIRATORY SOC JOURNALS LTD, ISSN:0903-1936

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