Publications
75 results found
Dewa L, Kalniunas A, Orleans-Foli S, et al., 2021, Detecting signs of deterioration in young patients with serious mental illness: a systematic review, Systematic Reviews, Vol: 10, Pages: 1-8, ISSN: 2046-4053
BackgroundSerious mental illnesses (SMI) such as schizophrenia and bipolar disorder first develop between ages 14-25. Once diagnosed, young peoples’ health can deteriorate, and it is therefore vital to detect this early to prevent severe outcomes including hospitalisations and deaths by suicide. The main study aim is to describe and discuss observational studies that examine signs of deterioration in young patients with SMI. MethodsA systematic review guided by the published protocol was conducted. Cumulative Index to Nursing and allied Health Literature (CINAHL), MEDLINE, Embase, PsycINFO, Health Management Information Consortium (HMIC) and Web of Science were searched against pre-defined criteria until March 1st 2021. Observational studies were extracted according to design, country, participant, indicator, outcome and main finding categories. Quality was assessed independently using the Newcastle Ottawa Scale (NOS). ResultsOf the 15788 publications identified, 5 studies were included and subjected to narrative synthesis. Two indicators of mental health deterioration were identified: cognitive functioning (decline, worsening and poor school/academic performance) and expressed emotion status. Indicators revealed mixed views on predicting deterioration. Worsening cognitive functioning and expressed emotion status significantly predicted medication non-adherence and relapse respectively. However, a decline in cognitive functioning (poor academic performance) was not found to significantly correlate to deaths by suicide. Study quality was mostly poor and associations between indicators and varied outcomes were weak. The heterogeneous nature of the data made comparisons difficult and did not allow for further statistical analysis. ConclusionTo our knowledge, this is the first review of observational studies to identify indicators of deterioration in young patients with SMI. Worsening cognitive functioning and expressed emotion status could indicate non-adherence
Barmparessou Z, Korkontzelou A, Ioannou M, et al., 2021, High prevalence of mild asthma among asthmatics visiting emergency department (ED), Publisher: EUROPEAN RESPIRATORY SOC JOURNALS LTD, ISSN: 0903-1936
Athanasiou N, Pappa S, Patrinos S, et al., 2021, Depression, anxiety, traumatic stress and burnout in healthcare workers (HCWs) during the COVID-19 pandemic in Greece:a multi-center, cross-sectional study, European-Respiratory-Society (ERS) International Congress, Publisher: EUROPEAN RESPIRATORY SOC JOURNALS LTD, ISSN: 0903-1936
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- Citations: 1
Barmparessou Z, Pappa S, Pappas A, et al., 2021, Sex differences in mental health of hospitalized patients with COVID-19, Publisher: EUROPEAN RESPIRATORY SOC JOURNALS LTD, ISSN: 0903-1936
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- Citations: 2
Athanasiou N, Pappa S, Pataka A, et al., 2021, Sleep disorders in healthcare workers(HCWs) working in the frontline during the first wave of the COVID-19 pandemic, Publisher: EUROPEAN RESPIRATORY SOC JOURNALS LTD, ISSN: 0903-1936
Athanasiou N, Pappa S, Mpousiou D, et al., 2021, Smoking of healthcare workers(HCWs) working in reference hospitals during the first wave of the COVID-19 pandemic, Publisher: EUROPEAN RESPIRATORY SOC JOURNALS LTD, ISSN: 0903-1936
Mason K, Barnett J, Pappa S, 2021, Effectiveness of 2-year treatment with aripiprazole long-acting injectable and comparison with paliperidone palmitate, THERAPEUTIC ADVANCES IN PSYCHOPHARMACOLOGY, Vol: 11, ISSN: 2045-1253
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- Citations: 9
Pungor K, Sanchez P, Pappa S, et al., 2021, The Patient, Investigator, Nurse, Carer Questionnaire (PINC-Q): a cross-sectional, retrospective, non-interventional study exploring the impact of less frequent medication administration with paliperidone palmitate 3-monthly as maintenance treatment for schizophrenia, BMC PSYCHIATRY, Vol: 21
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- Citations: 5
Dewa L, Lawrence-Jones A, Kalorkoti C, et al., 2021, Reflections, impact and recommendations of a co-produced qualitative study with young people who have experience of mental health difficulties, Health Expectations, Vol: 24, Pages: 134-146, ISSN: 1369-6513
BackgroundThere is limited evidence of genuine equal partnership where power is shared with young people with mental health difficulties throughout all research stages, particularly in data collection and analysis.ObjectiveTo describe how our qualitative study, exploring young peoples’ perceptions on the feasibility of using technology to detect mental health deterioration, was co-produced using principles of co-production, whilst reflecting on impact, challenges and recommendations.MethodsYoung people with experience of mental health difficulties were appointed and then worked with researchers throughout all research stages. The study was evaluated against the five principles of co-production. Reflections from researchers and young people were collected throughout.ResultsSeven young people formed an initial Young People's Advisory Group (YPAG); three became co-researchers. Reflection was key throughout the process. Sharing power became easier and more evident as trust, confidence and mutual respect grew over time, particularly after a safe space was established. The safe space was crucial for open discussions, and our WhatsApp group enabled continual communication, support and shared decision-making. The resulting co-produced topic guide, coding framework, thematic map, papers and presentations demonstrated significant impact.ConclusionsTo our knowledge, this is the first qualitative mental health study to be co-produced using the principles of co-production. Our rigorous assessment can be utilized as an informative document to help others to produce meaningful co-produced future research. Although co-production takes time, it makes significant impact to the research, researchers and co-researchers. Flexible funding for spontaneous suggestions from co-researchers and more time for interview training is recommended.
Pappa S, Barnett J, Berges I, et al., 2021, Tired, Worried and Burned Out, but Still Resilient: A Cross-Sectional Study of Mental Health Workers in the UK during the COVID-19 Pandemic, INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH, Vol: 18
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- Citations: 34
Pappa S, Athanasiou N, Sakkas N, et al., 2021, From Recession to Depression? Prevalence and Correlates of Depression, Anxiety, Traumatic Stress and Burnout in Healthcare Workers during the COVID-19 Pandemic in Greece: A Multi-Center, Cross-Sectional Study, INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH, Vol: 18
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- Citations: 35
Pappa S, Giannakoulis VG, Papoutsi E, et al., 2021, Author reply - Letter to the editor "The challenges of quantifying the psychological burden of COVID-19 on heathcare workers", BRAIN BEHAVIOR AND IMMUNITY, Vol: 92, Pages: 209-210, ISSN: 0889-1591
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- Citations: 9
Pappa S, Ntella V, Giannakas T, et al., 2021, Prevalence of depression, anxiety, and insomnia among healthcare workers during the COVID-19 pandemic: A systematic review and meta-analysis (vol 88, pg 901, 2020), BRAIN BEHAVIOR AND IMMUNITY, Vol: 92, Pages: 245-245, ISSN: 0889-1591
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- Citations: 1
Puntis S, Whiting D, Pappa S, et al., 2021, Development and external validation of an admission risk prediction model after treatment from early intervention in psychosis services, TRANSLATIONAL PSYCHIATRY, Vol: 11, ISSN: 2158-3188
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- Citations: 7
Pappa S, Mason K, Barnett J, 2020, A five-year follow up study of a naturalistic cohort treated with long-acting injectable antipsychotics, 33rd Congress of the European-College-of-Neuropsychopharmacology (ECNP), Publisher: ELSEVIER, Pages: S471-S471, ISSN: 0924-977X
Pappa S, Barnett J, Mason K, 2020, Real-world effectiveness of aripiprazole long-acting injectable, 33rd Congress of the European-College-of-Neuropsychopharmacology (ECNP), Publisher: ELSEVIER, Pages: S472-S472, ISSN: 0924-977X
Korkontzelou A, Driva S, Schoretsaniti S, et al., 2020, Smoking cessation in patients with Diabetes Mellitus (DM), Publisher: EUROPEAN RESPIRATORY SOC JOURNALS LTD, ISSN: 0903-1936
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- Citations: 1
Pappa S, Patrinos S, Sakkas N, et al., 2020, COPD patients continue to smoke after being diagnosed for COPD, Publisher: EUROPEAN RESPIRATORY SOC JOURNALS LTD, ISSN: 0903-1936
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- Citations: 2
Pappa S, Patrinos S, Sakka E, et al., 2020, Mental health disorders as barries to quit for asthmatic smokers, Publisher: EUROPEAN RESPIRATORY SOC JOURNALS LTD, ISSN: 0903-1936
Barmparessou Z, Korkontzelou A, Ioannou M, et al., 2020, The majority of patients that suffer an asthma attack at the Emergency Room (ER) are mild asthmatics, Publisher: EUROPEAN RESPIRATORY SOC JOURNALS LTD, ISSN: 0903-1936
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- Citations: 1
Crawford MJ, Thana L, Evans R, et al., 2020, Switching antipsychotic medication to reduce sexual dysfunction in people with psychosis: the REMEDY RCT, HEALTH TECHNOLOGY ASSESSMENT, Vol: 24, Pages: 1-+, ISSN: 1366-5278
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- Citations: 6
Pappa S, Ntella V, Giannakas T, et al., 2020, Prevalence of depression, anxiety, and insomnia among healthcare workers during the COVID-19 pandemic: A systematic review and meta-analysis, BRAIN BEHAVIOR AND IMMUNITY, Vol: 88, Pages: 901-907, ISSN: 0889-1591
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- Citations: 1960
Brinia A, Barmparessou Z, Vichos N, et al., 2020, Characteristics of patients admitted with asthma attacks in the emergency department of a University Hospital, European-Academy-of-Allergology-and-Clinical-Immunology Digital Congress (EAACI), Publisher: WILEY, Pages: 409-410, ISSN: 0105-4538
Attal J, Lahaye M, Leopold K, et al., 2020, Patient, investigator, nurse, carer questionnaire (PINC-Q): exploring the impact of paliperidone palmitate 3-monthly administration in the maintenance treatment of schizophrenia from four key stakeholders, Publisher: CAMBRIDGE UNIV PRESS, Pages: S256-S257, ISSN: 0924-9338
Pappa S, Mason K, 2020, Partial compliance with long-acting paliperidone palmitate and impact on hospitalization: a 6-year mirror-image study, THERAPEUTIC ADVANCES IN PSYCHOPHARMACOLOGY, Vol: 10, ISSN: 2045-1253
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- Citations: 21
Papoutsi E, Giannakoulis VG, Ntella V, et al., 2020, Global burden of COVID-19 pandemic on healthcare workers, ERJ OPEN RESEARCH, Vol: 6
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- Citations: 59
Allen K, Baban A, Munjiza J, et al., 2020, DOES SWITCHING OR AUGMENTING HELP WITH ANTIPSYCHOTIC-RELATED SEXUAL DYSFUNCTION: SYSTEMATIC REVIEW, Congress of the Schizophrenia-International-Research-Society (SRIS), Publisher: OXFORD UNIV PRESS, Pages: S30-S31, ISSN: 0586-7614
Javed A, Arthur H, Curtis L, et al., 2019, Practical guidance on the use of lurasidone for the treatment of adults with schizophrenia, Neurology and Therapy, Vol: 8, Pages: 215-230, ISSN: 2193-8253
IntroductionLurasidone is an atypical antipsychotic that was approved in Europe in 2014 for the treatment of schizophrenia in adults aged ≥ 18 years. Clinical experience with lurasidone in Europe is currently limited, and there is therefore a need to provide practical guidance on using lurasidone for the treatment of adults with schizophrenia.MethodsA panel of European psychiatrists with extensive experience of prescribing lurasidone was convened to provide recommendations on using lurasidone to treat adults with schizophrenia.ResultsExtensive evidence from clinical trials and the panel’s clinical experience suggest that lurasidone is as effective as other atypical agents, with the possible exception of clozapine. Lurasidone is associated with a lower propensity for metabolic side effects (in particular, weight gain) and hyperprolactinaemia than most other atypical antipsychotics and has a relatively benign neurocognitive side effect profile. Patients switching to lurasidone from another antipsychotic may experience weight reduction and/or improvements in the ability to focus/concentrate. Most side effects with lurasidone (such as somnolence) are transitory, easily managed and/or ameliorated by dose adjustment. Akathisia and extrapyramidal symptoms may occur in a minority of patients, but these can be managed effectively with dose adjustment, adjunctive therapy and/or psychosocial intervention.ConclusionsGiven the crucial importance of addressing the physical as well as mental healthcare needs of patients, lurasidone is a rational therapeutic choice for adults with schizophrenia, both in the acute setting and over the long term.FundingSunovion Pharmaceuticals Europe Ltd.
Allen K, Baban A, Munjiza J, et al., 2019, Management of Antipsychotic-Related Sexual Dysfunction: Systematic Review, JOURNAL OF SEXUAL MEDICINE, Vol: 16, Pages: 1978-1987, ISSN: 1743-6095
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- Citations: 11
Pappa S, Mason K, Howard E, 2019, Long-term effects of paliperidone palmitate on hospital stay and treatment continuation, INTERNATIONAL CLINICAL PSYCHOPHARMACOLOGY, Vol: 34, Pages: 305-311, ISSN: 0268-1315
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- Citations: 11
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