Publications
664 results found
Faria A, Myerson JS, Puglisi M, et al., 2009, The value of day 8 blood count in treatment decisions when using oral vinorelbine in non-small cell lung cancer (NSCLC) patients, Publisher: ELSEVIER IRELAND LTD, Pages: S4-S4, ISSN: 0169-5002
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- Citations: 1
Baird R, Mikropoulos C, Ashley S, et al., 2009, Audit of epidermal growth factor receptor (EGFR) expression by immunohistochemistry (IHC) using Dako and Ventana clones in non-small cell lung cancer (NSCLC), Publisher: ELSEVIER IRELAND LTD, Pages: S2-S3, ISSN: 0169-5002
Drilon AD, Popat S, Bhuchar G, et al., 2008, Extraskeletal Myxoid Chondrosarcoma A Retrospective Review From 2 Referral Centers Emphasizing Long-term Outcomes With Surgery and Chemotherapy, CANCER, Vol: 113, Pages: 3364-3371, ISSN: 0008-543X
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- Citations: 105
Sirohi B, Arnedos M, Popat S, et al., 2008, Platinum-based chemotherapy in triple-negative breast cancer, ANNALS OF ONCOLOGY, Vol: 19, Pages: 1847-1852, ISSN: 0923-7534
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- Citations: 168
Dernedde U, Chan S, Sykes H, et al., 2008, South West London Cancer Network (SWLCN) audit of patients with chemotherapy-induced febrile neutropenia (CIFN), Publisher: AMER SOC CLINICAL ONCOLOGY, ISSN: 0732-183X
Sirohi B, Arnedos M, Popat S, et al., 2008, Platinum-based chemotherapy in triple-negative (TN) breast cancer, Publisher: AMER SOC CLINICAL ONCOLOGY, ISSN: 0732-183X
Carden CP, Myerson JS, Popat S, et al., 2008, Good vibrations and the power of positron thinking: Positron emission tomography and endoscopic ultrasound in staging of mesothelioma - Two case reports, JOURNAL OF THORACIC ONCOLOGY, Vol: 3, Pages: 539-541, ISSN: 1556-0864
Ho GF, Popat S, Nutting C, 2008, Induction and concurrent chemoradiotherapy for non-small cell lung cancer (NSCLC) using cisplatin and vinorelbine, Publisher: ELSEVIER IRELAND LTD, Pages: S18-S18, ISSN: 0169-5002
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- Citations: 1
Brunetto A, Carden CP, Ashley S, et al., 2008, Dose intensity in advanced non-small cell lung cancer, Publisher: ELSEVIER IRELAND LTD, Pages: S20-S20, ISSN: 0169-5002
Popat S, Smith IE, 2008, Therapy Insight: anthracyclines and trastuzumab-the optimal management of cardiotoxic side effects., Nat Clin Pract Oncol, ISSN: 1743-4262
Anthracyclines and trastuzumab are key agents in the management of patients with breast cancer, and have revolutionized the management of both early-stage and advanced-stage disease. The use of anthracyclines, however, can be compromised by the potential for cardiotoxicity; trastuzumab also has the potential for causing cardiotoxicity in patients receiving concurrent or prior anthracyclines. Although its development is treatment limiting, cardiotoxicity can be minimized with appropriate clinical care and drug scheduling. We discuss the efficacy of trastuzumab, its potential for cardiac compromise, and its interaction with anthracyclines. We highlight biological mechanisms that might be responsible for cardiotoxicity, describe the established and trial schedules of both agents, and discuss clinical strategies used to minimize the risk of developing cardiac failure through appropriate scheduling of trastuzumab with anthracyclines.
O'Brien MER, Yau T, Coward J, et al., 2008, Time and chemotherapy treatment trends in the treatment of elderly patients (age ≥ 70 years) with non-small cell lung cancer, CLINICAL ONCOLOGY, Vol: 20, Pages: 142-147, ISSN: 0936-6555
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- Citations: 5
Hughes S, Barbachano Y, Ashley S, et al., 2008, Time trends in the outcome of elderly patients with breast cancer, BREAST JOURNAL, Vol: 14, Pages: 158-163, ISSN: 1075-122X
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- Citations: 7
Popat S, Barbachano Y, Ashley S, et al., 2008, Erlotinib, docetaxel, and gefitinib in sequential cohorts with relapsed non-small cell lung cancer, LUNG CANCER, Vol: 59, Pages: 227-231, ISSN: 0169-5002
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- Citations: 13
Wilkins A, Popat S, Hughes S, et al., 2007, Malignant pleural mesothelioma: Two cases in first degree relatives, LUNG CANCER, Vol: 57, Pages: 407-409, ISSN: 0169-5002
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- Citations: 3
Sirohi B, Ashley S, Norton A, et al., 2007, Early response to platinum-based first-line chemotherapy in non-small cell lung cancer may predict survival, JOURNAL OF THORACIC ONCOLOGY, Vol: 2, Pages: 735-740, ISSN: 1556-0864
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- Citations: 24
Popat S, Hughes S, Papadopoulos P, et al., 2007, Recurrent responses to non-small cell lung cancer brain metastases with erlotinib, LUNG CANCER, Vol: 56, Pages: 135-137, ISSN: 0169-5002
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- Citations: 38
Popat S, Zhao D, Chen Z, et al., 2007, Relationship between chromosome 18q status and colorectal cancer prognosis: A prospective, blinded analysis of 280 patients, ANTICANCER RESEARCH, Vol: 27, Pages: 627-633, ISSN: 0250-7005
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- Citations: 30
Tjellstroem B, Stenhammar L, Hoegberg L, et al., 2007, Gut microflora associated characteristics in first-degree relatives of children with celiac disease, SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY, Vol: 42, Pages: 1204-1208, ISSN: 0036-5521
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- Citations: 21
Price P, Sikora K, Illidge T, 2007, Treatment of Cancer, London, Publisher: Arnold
Popat S, Chen Z, Zhao D, et al., 2006, A prospective, blinded analysis of thymidylate synthase and p53 expression as prognostic markers in the adjuvant treatment of colorectal cancer, ANNALS OF ONCOLOGY, Vol: 17, Pages: 1810-1817, ISSN: 0923-7534
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- Citations: 52
Hubner RA, Muir KR, Liu J-F, et al., 2006, Genetic variants of <i>UGT1A6</i> influence risk of colorectal adenoma recurrence, CLINICAL CANCER RESEARCH, Vol: 12, Pages: 6585-6589, ISSN: 1078-0432
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- Citations: 23
Chandler IP, Popat S, Pan H, et al., 2006, A prospective study confirms mismatch repair status predicts outcome in colorectal cancer, 190th Meeting of the Pathological-Society-of-Great-Britain-and-Ireland, Publisher: JOHN WILEY & SONS LTD, Pages: 7-7, ISSN: 0022-3417
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- Citations: 2
Popat S, Lopez J, Chan S, et al., 2006, Palliative treatments for patients with inoperable gastroesophageal cancers., Int J Palliat Nurs, Vol: 12, Pages: 306-317, ISSN: 1357-6321
Most patients with cancers of the stomach, oesophagus or gastroesophageal junction ultimately develop metastatic or inoperable disease, rendering them incurable. They can, however, benefit from a variety of palliative interventions involving the multidisciplinary team, including chemotherapy, radiotherapy, endoluminal stenting, laser, or surgery. Often a combination of such strategies will be used to control symptoms, and maintain or improve quality of life. In this article, we review these multidisciplinary interventional approaches in patients with gastroesophageal cancers, and highlight future trends.
Popat S, Wort R, Houlston RS, 2006, Inter-relationship between microsatellite instability, thymidylate synthase expression, and p53 status in colorectal cancer: implications for chemoresistance, BMC CANCER, Vol: 6
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- Citations: 20
Yau T, Ashley S, Popat S, et al., 2006, Time and chemotherapy treatment trends in the treatment of elderly patients (age ≥ 70 years) with small cell lung cancer, BRITISH JOURNAL OF CANCER, Vol: 94, Pages: 18-21, ISSN: 0007-0920
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- Citations: 18
Popat S, Houlston RS, 2006, Nonmedullary thyroid cancer and the role of the geneticist., Practical management of thyroid cancer: a multidisciplinary approach, Editors: Mazzaferri, Harmer, Kendall-Taylor, Mallick, London, Publisher: Springer-Verlag, Pages: 281-302
Popat S, Houlston RS, 2005, Re: Reporting recommendations for tumor marker prognostic studies (REMARK), JOURNAL OF THE NATIONAL CANCER INSTITUTE, Vol: 97, Pages: 1855-1855, ISSN: 0027-8874
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- Citations: 7
Popat S, Houlston RS, 2005, A systematic review and meta-analysis of the relationship between chromosome 18q genotype, DCC status and colorectal cancer prognosis, EUROPEAN JOURNAL OF CANCER, Vol: 41, Pages: 2060-2070, ISSN: 0959-8049
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- Citations: 135
Sirohi B, Matakidou A, Benson C, et al., 2005, Early response to platinum-based chemotherapy in non small cell lung cancer (NSCLC) predicts survival unluike in mesotheliomas, 11th World Conference on Lung Cancer, Publisher: ELSEVIER IRELAND LTD, Pages: S91-S91, ISSN: 0169-5002
Yau T, Ashley S, Popat S, et al., 2005, Chemotherapy treatments outcome and toxicities in the treatment of elderly patients (age ≥ 70) with lung cancer, 11th World Conference on Lung Cancer, Publisher: ELSEVIER IRELAND LTD, Pages: S275-S275, ISSN: 0169-5002
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