Imperial College London

Professor Ramesh Wigneshweraraj

Faculty of MedicineDepartment of Infectious Disease

Professor of Molecular Microbiology



+44 (0)20 7594 1867s.r.wig




4.40BFlowers buildingSouth Kensington Campus





Research in the laboratory focuses on three interconnected topics:

RNA metabolism in long-term nutrient starved bacteria

Recent publications: Switzer et al 2020 McQuail et al 2020

Phage takeover of bacterial transcription and other processes

Recent publications: Mulvenna et al 2019 Tabib-Salazar et al 2019

NEW: Transcriptional regulatory basis of bacteriocin expression in mono and polymicrobial environments (in collaboration with Syngulon)

If you are interested in collaborating with us please get in touch. We are always looking for enthusiastic MRes, MSc or PhD who are keen to join the group or visiting students looking to spend some time in the UK working in the area of molecular bacteriology. 



McQuail J, Carpousis AJ, Wigneshweraraj S, 2021, The association between Hfq and RNase E in long-term nitrogen-starved Escherichia coli, Molecular Microbiology, ISSN:0950-382X

Bakovic J, Yu BYK, Silva D, et al., 2021, Redox Regulation of the Quorum-sensing Transcription Factor AgrA by Coenzyme A, Antioxidants, Vol:10

Zhyvoloup A, Yu BYK, Bakovic J, et al., 2020, Analysis of disulphide bond linkage between CoA and protein cysteine thiols during sporulation and in spores of Bacillus species, Fems Microbiology Letters, Vol:367, ISSN:0378-1097

Switzer A, Burchell L, McQuail J, et al., 2020, The adaptive response to long-term nitrogen starvation in Escherichia coli requires the breakdown of allantoin., Journal of Bacteriology, Vol:202, ISSN:0021-9193, Pages:1-11

McQuail J, Switzer A, Burchell L, et al., 2020, The RNA-binding protein Hfq assembles into foci-like structures in nitrogen starved Escherichia coli, Journal of Biological Chemistry, Vol:295, ISSN:0021-9258, Pages:12355-12367

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