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@article{Ramasamy:2017:2017/5046953,
author = {Ramasamy, SK},
doi = {2017/5046953},
journal = {Stem Cells International},
title = {Structure and functions of blood vessels and vascular niches in bone},
url = {http://dx.doi.org/10.1155/2017/5046953},
volume = {2017},
year = {2017}
}

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TY  - JOUR
AB  - Bone provides nurturing microenvironments for an array of cell types that coordinate important physiological functions of the skeleton, such as energy metabolism, mineral homeostasis, osteogenesis, and haematopoiesis. Endothelial cells form an intricate network of blood vessels that organises and sustains various microenvironments in bone. The recent identification of heterogeneity in the bone vasculature supports the existence of multiple vascular niches within the bone marrow compartment. A unique combination of cells and factors defining a particular microenvironment, supply regulatory signals to mediate a specific function. This review discusses recent developments in our understanding of vascular niches in bone that play a critical role in regulating the behaviour of multipotent haematopoietic and mesenchymal stem cells during development and homeostasis.
AU  - Ramasamy,SK
DO  - 2017/5046953
PY  - 2017///
SN  - 1687-9678
TI  - Structure and functions of blood vessels and vascular niches in bone
T2  - Stem Cells International
UR  - http://dx.doi.org/10.1155/2017/5046953
UR  - http://hdl.handle.net/10044/1/50490
VL  - 2017
ER  -

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