Imperial College London
Alternate

ProfessorSaraRankin

Faculty of Medicine, National Heart & Lung Institute

Professor of Leukocyte and Stem Cell Biology
 
 
 
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Contact

 

+44 (0)20 7594 3172s.rankin

 
 
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Assistant

 

Ms Georgina Moss +44 (0)20 7594 2151

 
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Location

 

Office no. 351Sir Alexander Fleming BuildingSouth Kensington Campus

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Summary

 

Publications

Citation

BibTex format

@article{De:2018:10.1111/eci.12949,
author = {De, Filippo K and Rankin, SM},
doi = {10.1111/eci.12949},
journal = {European Journal of Clinical Investigation},
title = {CXCR4, the master regulator of neutrophil trafficking in homoeostasis and disease.},
url = {http://dx.doi.org/10.1111/eci.12949},
volume = {48},
year = {2018}
}
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RIS format (EndNote, RefMan)

TY  - JOUR
AB  - BACKGROUND: Chemokines play a critical role in orchestrating the distribution and trafficking of neutrophils in homoeostasis and disease. RESULTS: The CXCR4/CXCL12 chemokine axis has been identified as a central regulator of these processes. CONCLUSION: In this review, we focus on the role of CXCR4/CXCL12 chemokine axis in regulating neutrophil release from the bone marrow and the trafficking of senescent neutrophils back to the bone marrow for clearance under homoeostasis and disease. We also discuss the role of CXCR4 in fine-tuning neutrophil responses in the context of inflammation.
AU  - De,Filippo K
AU  - Rankin,SM
DO  - 10.1111/eci.12949
PY  - 2018///
SN  - 0014-2972
TI  - CXCR4, the master regulator of neutrophil trafficking in homoeostasis and disease.
T2  - European Journal of Clinical Investigation
UR  - http://dx.doi.org/10.1111/eci.12949
UR  - https://www.ncbi.nlm.nih.gov/pubmed/29734477
UR  - http://hdl.handle.net/10044/1/60340
VL  - 48
ER  -
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