Imperial College London
Alternate

ProfessorSalmanRawaf

Faculty of Medicine, School of Public Health

Director of WHO Collaborating Centre
 
 
 
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Contact

 

+44 (0)20 7594 8814s.rawaf

 
 
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Assistant

 

Ms Ela Augustyniak +44 (0)20 7594 8603

 
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Location

 

311Reynolds BuildingCharing Cross Campus

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Summary

 

Publications

Citation

BibTex format

@article{GBD:2019:10.1016/S2468-1253(19)30347-4,
author = {GBD, 2017 Pancreatic Cancer Collaborators},
doi = {10.1016/S2468-1253(19)30347-4},
journal = {Lancet Gastroenterology and Hepatology},
pages = {934--947},
title = {The global, regional, and national burden of pancreatic cancer and its attributable risk factors in 195 countries and territories, 1990-2017: a systematic analysis for the Global Burden of Disease Study 2017.},
url = {http://dx.doi.org/10.1016/S2468-1253(19)30347-4},
volume = {4},
year = {2019}
}
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RIS format (EndNote, RefMan)

TY  - JOUR
AB  - BACKGROUND: Worldwide, both the incidence and death rates of pancreatic cancer are increasing. Evaluation of pancreatic cancer burden and its global, regional, and national patterns is crucial to policy making and better resource allocation for controlling pancreatic cancer risk factors, developing early detection methods, and providing faster and more effective treatments. METHODS: Vital registration, vital registration sample, and cancer registry data were used to generate mortality, incidence, and disability-adjusted life-years (DALYs) estimates. We used the comparative risk assessment framework to estimate the proportion of deaths attributable to risk factors for pancreatic cancer: smoking, high fasting plasma glucose, and high body-mass index. All of the estimates were reported as counts and age-standardised rates per 100000 person-years. 95% uncertainty intervals (UIs) were reported for all estimates. FINDINGS: In 2017, there were 448000 (95% UI 439000-456000) incident cases of pancreatic cancer globally, of which 232000 (210000-221000; 51·9%) were in males. The age-standardised incidence rate was 5·0 (4·9-5·1) per 100000 person-years in 1990 and increased to 5·7 (5·6-5·8) per 100000 person-years in 2017. There was a 2·3 times increase in number of deaths for both sexes from 196000 (193000-200000) in 1990 to 441000 (433000-449000) in 2017. There was a 2·1 times increase in DALYs due to pancreatic cancer, increasing from 4·4 million (4·3-4·5) in 1990 to 9·1 million (8·9-9·3) in 2017. The age-standardised death rate of pancreatic cancer was highest in the high-income super-region across all years from 1990 to 2017. In 2017, the highest age-standardised death rates were observed in Greenland (17·4 [15·8-19·0] per 100000 person-years) and Uruguay (12·1 [10·9-13·5] per 100000 person-years). These countri
AU  - GBD,2017 Pancreatic Cancer Collaborators
DO  - 10.1016/S2468-1253(19)30347-4
EP  - 947
PY  - 2019///
SN  - 2468-1253
SP  - 934
TI  - The global, regional, and national burden of pancreatic cancer and its attributable risk factors in 195 countries and territories, 1990-2017: a systematic analysis for the Global Burden of Disease Study 2017.
T2  - Lancet Gastroenterology and Hepatology
UR  - http://dx.doi.org/10.1016/S2468-1253(19)30347-4
UR  - https://www.ncbi.nlm.nih.gov/pubmed/31648972
UR  - https://www.sciencedirect.com/science/article/pii/S2468125319303474?via%3Dihub
UR  - http://hdl.handle.net/10044/1/74707
VL  - 4
ER  -
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