Imperial College London
Alternate

Steven Riley

Faculty of Medicine, School of Public Health

Professor of Infectious Disease Dynamics
 
 
 
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Contact

 

+44 (0)20 7594 2452s.riley

 
 
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Location

 

UG8Medical SchoolSt Mary's Campus

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Summary

 

Publications

Citation

BibTex format

@unpublished{Ward:2021,
author = {Ward, H and Whitaker, M and Tang, SN and Atchison, C and Darzi, A and Donnelly, C and Diggle, P and Ashby, D and Riley, S and Barclay, W and Elliott, P and Cooke, G},
title = {Vaccine uptake and SARS-CoV-2 antibody prevalence among  207,337 adults during May 2021 in England: REACT-2 study},
url = {http://hdl.handle.net/10044/1/90339},
year = {2021}
}
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RIS format (EndNote, RefMan)

TY  - UNPB
AB  - Background The programme to vaccinate adults in England has been rapidly implementedsince it began in December 2020. The community prevalence of SARS-CoV-2 anti-spikeprotein antibodies provides an estimate of total cumulative response to natural infection andvaccination. We describe the distribution of SARS-CoV-2 IgG antibodies in adults inEngland in May 2021 at a time when approximately 7 in 10 adults had received at least onedose of vaccine.Methods Sixth round of REACT-2 (REal-time Assessment of Community Transmission-2),a cross-sectional random community survey of adults in England, from 12 to 25 May 2021;207,337 participants completed questionnaires and self-administered a lateral flowimmunoassay test producing a positive or negative result.Results Vaccine coverage with one or more doses, weighted to the adult population inEngland, was 72.9% (95% confidence interval 72.7-73.0), varying by age from 25.1% (24.5-25.6) of those aged 18 to 24 years, to 99.2% (99.1-99.3) of those 75 years and older. Inadjusted models, odds of vaccination were lower in men (odds ratio [OR] 0.89 [0.85-0.94])than women, and in people of Black (0.41 [0.34-0.49]) compared to white ethnicity. Therewas higher vaccine coverage in the least deprived and highest income households. Peoplewho reported a history of COVID-19 were less likely to be vaccinated (OR 0.61 [0.55-0.67]).There was high coverage among health workers (OR 9.84 [8.79-11.02] and care workers (OR4.17 [3.20-5.43]) compared to non-key workers, but lower in hospitality and retail workers(OR 0.73 [0.64-0.82] and 0.77 [0.70-0.85] respectively) after adjusting for age and keycovariates.
AU  - Ward,H
AU  - Whitaker,M
AU  - Tang,SN
AU  - Atchison,C
AU  - Darzi,A
AU  - Donnelly,C
AU  - Diggle,P
AU  - Ashby,D
AU  - Riley,S
AU  - Barclay,W
AU  - Elliott,P
AU  - Cooke,G
PY  - 2021///
TI  - Vaccine uptake and SARS-CoV-2 antibody prevalence among  207,337 adults during May 2021 in England: REACT-2 study
UR  - http://hdl.handle.net/10044/1/90339
ER  -
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