Imperial College London

Dr Sadia Saeed

Faculty of MedicineDepartment of Metabolism, Digestion and Reproduction

Research Associate



+44 (0)20 7594 6537s.saeed08




Burlington DanesHammersmith Campus





I am postdoctoral fellow working in the area of genetics and functional genomics of obesity at the Department of Metabolism, Digestion and Reproduction. I have obtained my PhD degree in Human Genetics from the Department of Common Diseases, Imperial College London in 2016. Following completion of my doctoral degree I have worked as a post-doctorate and Research Associate in the same department. Later I obtained a position of Research Scientist at the University of Lille, CNRS France. Currently I am working in Imperial College London in MRC funded project related to functional characterization of genes associated with severe obesity identified from consanguineous pedigrees. During the past 10 years I have developed and coordinated active and viable research collaboration with universities and major hospital in Pakistan and my research has been mainly focused on genetic causality of metabolic disease in Pakistani population – a fact obvious from my research contributions. Apart from purely academic work, my important contribution to the community has been to spread awareness amongst paediatricians and physicians the importance of molecular screening of patients for classifying major metabolic disease to enable individualised management of patients and precision medication. I have personally helped and facilitated molecular diagnosis of a number of patients attending local hospitals referred to me, on a compassionate basis.



Talbot F, Feetham CH, Mokrosiński J, et al., 2023, A rare human variant that disrupts GPR10 signalling causes weight gain in mice., Nat Commun, Vol:14

Saeed S, Janjua QM, Haseeb A, et al., 2022, Rare Variant Analysis of Obesity-Associated Genes in Young Adults With Severe Obesity From a Consanguineous Population of Pakistan, Diabetes, Vol:71, ISSN:0012-1797, Pages:694-705

Saeed S, Arslan M, Manzoor J, et al., 2020, Genetic Causes of Severe Childhood Obesity: A Remarkably High Prevalence in an Inbred Population of Pakistan, Diabetes, Vol:69, ISSN:0012-1797, Pages:1424-1438

Saeed S, Arslan M, Froguel P, 2018, Genetics of Obesity in Consanguineous Populations: Toward Precision Medicine and the Discovery of Novel Obesity Genes, Obesity, Vol:26, ISSN:1930-7381, Pages:474-484

Saeed S, Bonnefond A, Tamanini F, et al., 2018, Loss-of-function mutations in ADCY3 cause monogenic severe obesity, Nature Genetics, Vol:50, ISSN:1061-4036, Pages:175-179

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