Imperial College London


Faculty of MedicineNational Heart & Lung Institute

Professor of Paediatric Respiratory Medicine



+44 (0)20 7594 3167s.saglani




112Sir Alexander Fleming BuildingSouth Kensington Campus





Management of Preschool Wheeze

  • Use of molecular profiling to determine optimal management for moderate to severe preschool wheeze - NIHR, Prinicipal Investigator
  • Granulocyte activation and functional interactions with the bronchial epithelium and asthma control in children - Asthma UK, Principal Investigator
  • Gene-environment interactions mediating preschool wheeze: the role of 17q21, farmyard microbes and innate cytokines - Asthma UK, Principal Investigator
  • Patterns of airway infection and inflammation distinguish pathophysiological phenotypes in preschool wheezers independently of symptom pattern - British Lung Foundation, Principal Investigator

Mechanisms mediating Paediatric Severe Asthma

  • Role of innate lymphoid cells in mediating severe asthma in children
  • Interactions between T helper cells and innate lymphoid cells in steroid resistance in paediatric severe therapy resistant asthma


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Breathing Together Study - Wellcome Trust Strategic Award:

Pulmonary epithelial barrier and immunological functions at birth and in early life – key determinants of the development of asthma?, Principal Investigator at Imperial and Chelsea & Westminster Hospital