Publications
283 results found
Saxena S, Ismael Z, Murray ML, et al., 2014, Oral penicillin prescribing for children in the UK: a comparison with <i>BNF</i> <i>for Children</i> age-band recommendations, BRITISH JOURNAL OF GENERAL PRACTICE, Vol: 64, Pages: E217-E222, ISSN: 0960-1643
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- Citations: 10
Chatu S, Saxena S, Subramanian V, et al., 2014, The Impact of Timing and Duration of Thiopurine Treatment on First Intestinal Resection in Crohn's Disease: National UK Population-Based Study 1989-2010, AMERICAN JOURNAL OF GASTROENTEROLOGY, Vol: 109, Pages: 409-416, ISSN: 0002-9270
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- Citations: 54
Murray J, Bottle A, Sharland M, et al., 2014, Risk Factors for Hospital Admission with RSV Bronchiolitis in England: A Population-Based Birth Cohort Study, PLOS ONE, Vol: 9, ISSN: 1932-6203
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- Citations: 125
Chhaya V, Saxena S, Cecil E, et al., 2014, Increasing colectomy rates over time in ulcerative colitis and the impact of thiopurines: A nationwide cohort study, JOURNAL OF CROHNS & COLITIS, Vol: 8, Pages: S53-S54, ISSN: 1873-9946
Chhaya V, Pollok R, Cecil E, et al., 2014, Adolescent and young adults are more likely to require total colectomy in ulcerative colitis: UK population based cohort study, JOURNAL OF CROHNS & COLITIS, Vol: 8, Pages: S33-S33, ISSN: 1873-9946
Falconer CL, Park MH, Croker H, et al., 2014, Can the relationship between ethnicity and obesity-related behaviours among school-aged children be explained by deprivation? A cross-sectional study, BMJ OPEN, Vol: 4, ISSN: 2044-6055
Saxena A, Laverty AA, 2014, Confronting child obesity in primary care, British Journal of General Practice
Chatu S, Subramanian V, Saxena S, et al., 2014, The Role of Thiopurines in Reducing the Need for Surgical Resection in Crohn's Disease: A Systematic Review and Meta-Analysis, AMERICAN JOURNAL OF GASTROENTEROLOGY, Vol: 109, Pages: 23-35, ISSN: 0002-9270
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- Citations: 77
Koshy E, Curcin V, Bottle A, et al., 2013, Re: Sore throat consultations in general practice prior to tonsillectomy among eight hundred and sixty-three children in England: is this in accordance with the SIGN guidelines? Response, CLINICAL OTOLARYNGOLOGY, Vol: 38, Pages: 560-560, ISSN: 1749-4478
Cecil E, Bottle A, Sharland M, et al., 2013, Have contractual changes in primary care affected unplanned short stay childhood admissions in England? National time trends study 2001–11, The Lancet, Vol: 382, ISSN: 0140-6736
Background: Short-stay unplanned hospital admissions in children have much increased over the past decade everywhere. Timely primary care prevents unplanned admissions into hospital and short stays admissions can be regarded as a proxy indicator of conditions that could be dealt with in primary care. In April, 2004, major changes in primary care occurred across England, with the introduction of the new general practitioner (GP) contract. Out-of-hours health provision ceased to be the responsibility of GPs, and alternative services introduced to compensate were unpopular with patients. In-hours health-care provision also altered; the introduction of financial incentives for chronic disease management, having been aimed at adults, altered the availability of GP appointments for children. Reduced access to primary care in and out of hours could have delayed health seeking and potentially driven parents to use emergency care. We investigated the effect of these changes on children.Methods: We applied a segmented population-based time trends study design, using Hospital Episode Statistics data, in children aged 0–14 years who were admitted in England between April 1, 2001, and March 31, 2004, and between April 1, 2004, and March 31, 2011. The outcome measures were age-specific unplanned admission rates for total and very short stays (same day discharge). The unit of analysis was middle super output area and we applied a generalised estimating equations model, adjusting for deprivation and autocorrelation. Indicator variables modelled a step change at and a trend change after service changes in April, 2004. Interaction coefficients estimated the effect modification of age on the baseline trend and point of intervention.Findings: Age-standardised rates increased by 15% between 2001–02 and 2010–11, from 64·7 (95% CI 64·6–64·9) to 74·3 (74·2–74·5) unplanned admissions per 1000 children. Segmented trends
Mainous AG, Johnson SP, Saxena SK, et al., 2013, Inpatient Bariatric Surgery Among Eligible Black and White Men and Women in the United States, 1999-2010, AMERICAN JOURNAL OF GASTROENTEROLOGY, Vol: 108, Pages: 1218-1223, ISSN: 0002-9270
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- Citations: 42
Park MH, Falconer CL, Saxena S, et al., 2013, Perceptions of health risk among parents of overweight children: A cross-sectional study within a cohort, PREVENTIVE MEDICINE, Vol: 57, Pages: 55-59, ISSN: 0091-7435
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- Citations: 25
Jones Nielsen JD, Laverty AA, Millett C, et al., 2013, Rising Obesity-Related Hospital Admissions among Children and Young People in England: National Time Trends Study, PLOS One
Koshy E, Curcin V, Bottle A, et al., 2013, Sore throat consultations in general practice prior to tonsillectomy among eight hundred and sixty-three children in England: is this in accordance with the SIGN guidelines?, CLINICAL OTOLARYNGOLOGY, Vol: 38, Pages: 266-270, ISSN: 1749-4478
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- Citations: 4
Murray J, Saxena S, Modi N, et al., 2013, Quality of routine hospital birth records and the feasibility of their use for creating birth cohorts, JOURNAL OF PUBLIC HEALTH, Vol: 35, Pages: 298-307, ISSN: 1741-3842
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- Citations: 24
Ahmad A, Laverty A, Aasheim E, et al., 2013, ELIGIBILITY FOR BARIATRIC SURGERY IN ENGLAND ACCORDING TO NICE GUIDELINES, Annual General Meeting of the British-Society-of-Gastroenterology, Publisher: BMJ PUBLISHING GROUP, Pages: A201-A201, ISSN: 0017-5749
Ahmad A, Laverty AA, Aasheim ET, et al., 2013, Eligibility for Bariatric Surgery Among Adults in England: Analysis of National Cross Sectional Survey, Publisher: W B SAUNDERS CO-ELSEVIER INC, Pages: S270-S270, ISSN: 0016-5085
Koshy E, Murray J, Bottle A, et al., 2012, Significantly increasing hospital admissions for acute throat infections among children in England: is this related to tonsillectomy rates?, ARCHIVES OF DISEASE IN CHILDHOOD, Vol: 97, Pages: 1064-1068, ISSN: 0003-9888
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- Citations: 16
Arrowsmith ME, Aicken CRH, Majeed A, et al., 2012, Interventions for increasing uptake of copper intrauterine devices: systematic review and meta-analysis, CONTRACEPTION, Vol: 86, Pages: 600-605, ISSN: 0010-7824
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- Citations: 9
Saxena S, 2012, Significant Events and Audit, General Practice at a Glance (BMA Book prize Winner 2015), Publisher: John Wiley & Sons, ISBN: 9781118518465
Significant Event Analysis, Audit and Research
Gnani S, McDonald H, Islam AFMS, et al., 2012, Patterns of healthcare use among adolescents attending an urban general practitioner led urgent care centre, Emergency Medical Journal
Adolescence is a time of increasing health and peak fitness, but also of increasing health risks. In the UK, primary care is free at the point of access, yet adolescents aged 10 to 19 years are the lowest users of primary care services, and disproportionately high users of emergency services. The effect of new general practitioner (GP) led urgent care centres in meeting the needs of adolescents are unknown.
Falconer C, Park M, Skow A, et al., 2012, Scoping the impact of the national child measurement programme feedback on the child obesity pathway: study protocol, BMC PUBLIC HEALTH, Vol: 12, ISSN: 1471-2458
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- Citations: 10
Saxena S, Francis N, Sharland M, 2012, Primary care of children: the unique role of GPs, BRITISH JOURNAL OF GENERAL PRACTICE, Vol: 62, Pages: 340-341, ISSN: 0960-1643
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- Citations: 21
Chatu S, Saxena S, Pilcher J, et al., 2012, Diagnostic accuracy of small intestine ultrasonography using an oral contrast agent in Crohn's disease: Comparative study from the UK, Clinical Radiology, Vol: 6, Pages: 553-559
AIM: To evaluate the usefulness of small intestine contrast-enhanced ultrasonography (SICUS) using an oral contrast agent in routine clinical practice by assessing the level of agreement with the established techniques, small bowel follow-through (SBFT) and computed tomography (CT), and diagnostic accuracy compared with the final diagnosis in the detection of small bowel Crohn's disease (CD) and luminal complications in a regional centre.MATERIALS AND METHODS: All symptomatic known or suspected cases of CD who underwent SICUS were retrospectively reviewed. The level of agreement between SICUS and SBFT, CT, histological findings, and C-reactive protein (CRP) level was assessed using kappa (κ) coefficient. Sensitivity was demonstrated using the final diagnosis as the reference standard defined by the outcome of clinical assessment, follow-up, and results of investigations other than SICUS.RESULTS: One hundred and forty-three patients underwent SICUS of these 79 (55%) were female. Eighty-six (60%) were known to have CD and 57 (40%) had symptoms suggestive of intestinal disease with no previous diagnosis. Forty-six (55%) of the known CD patients had had at least one previous surgical resection. The sensitivity of SICUS in detecting active small bowel CD in known CD and undiagnosed cases was 93%. The kappa coefficient was 0.88 and 0.91 with SBFT and CT, respectively. SICUS detected nine patients who had one or more small bowel strictures and six patients with a fistula all detected by SBFT or CT.CONCLUSION: SICUS is not only comparable to SBFT and CT but avoids radiation exposure and should be more widely adopted in the UK as a primary diagnostic procedure and to monitor disease complications in patients with CD
Jen M-H, Saxena S, Bottle A, et al., 2012, Assessment of administrative data for evaluating the shifting acquisition of <i>Clostridium difficile</i> infection in England, JOURNAL OF HOSPITAL INFECTION, Vol: 80, Pages: 229-237, ISSN: 0195-6701
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- Citations: 19
Chatu S, Saxena S, Subramanian V, et al., 2012, Time trends in rates of first surgical resection and thiopurine use in crohn's disease: retrospective cohort study, Vol: Suppl 2 A60
S Chatu, S Saxena, V Subramanian, V Curcin, G Yadegarfar, A Majeed, R C Pollok
Arrowsmith ME, Aicken CRH, Saxena S, et al., 2012, Strategies for improving the acceptability and acceptance of the copper intrauterine device, COCHRANE DATABASE OF SYSTEMATIC REVIEWS, ISSN: 1469-493X
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- Citations: 37
Bown MJ, Jones GT, Harrison SC, et al., 2011, Abdominal Aortic Aneurysm Is Associated with a Variant in Low-Density Lipoprotein Receptor-Related Protein 1, AMERICAN JOURNAL OF HUMAN GENETICS, Vol: 89, Pages: 619-627, ISSN: 0002-9297
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- Citations: 141
Williams N, Woodward H, Majeed A, et al., 2011, Primary care strategies to improve childhood immunisation uptake in developed countries: systematic review., JRSM Short Rep, Vol: 2
OBJECTIVES: To conduct a systematic review of strategies to optimize immunisation uptake within preschool children in developed countries. DESIGN: Systematic review. SETTING: Developed countries PARTICIPANTS: Preschool children who were due, or overdue, one or more of their routine primary immunisations. MAIN OUTCOME MEASURES: Increase in the proportion of the target population up to date with standard recommended universal vaccinations. RESULTS: Forty-six studies were included for analysis, published between 1980 and 2009. Twenty-six studies were randomized controlled trials, 11 were before and after trials, and nine were controlled intervention trials. Parental reminders showed a statistically significant increase in immunisation rates in 34% of included intervention arms. These effects were reported with both generic and specific reminders and with all methods of reminders and recall. Strategies aimed at immunisation providers were also shown to improve immunisation rates with a median change in immunisation rates of 7% when reminders were used, 8% when educational programmes were used and 19% when feedback programmes were used. CONCLUSION: General practitioners are uniquely positioned to influence parental decisions on childhood immunisation. A variety of strategies studied in primary care settings have been shown to improve immunisation rates, including parental and healthcare provider reminders.
Koshy E, Murray J, Bottle A, et al., 2011, Validity of using Hospital Episode Statistics data on monitoring disease trends Response, THORAX, Vol: 66, Pages: 827-828, ISSN: 0040-6376
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