Imperial College London
Portrait Picture

DrSanoojSoni

Faculty of Medicine, Department of Surgery & Cancer

Clinical Senior Lecturer in Critical and Perioperative Care
 
 
 
//

Contact

 

s.soni

 
 
//

Location

 

Commonwealth BuildingHammersmith Campus

//

Summary

 

Publications

Citation

BibTex format

@article{Watson:2022:10.1164/rccm.202107-1609rr,
author = {Watson, N and Brown, E and Ritchie, AI and Soni, S},
doi = {10.1164/rccm.202107-1609rr},
journal = {American Journal of Respiratory and Critical Care Medicine},
pages = {1470--1473},
title = {Recommended reading from the Imperial College, London fellows},
url = {http://dx.doi.org/10.1164/rccm.202107-1609rr},
volume = {205},
year = {2022}
}
Download

RIS format (EndNote, RefMan)

TY  - JOUR
AB  - Supplementary oxygen is widely used in critically unwell patients; however, the optimal regime of oxygen therapy is a topic of ongoing debate. Although hypoxemia is dangerous, in vitro evidence suggests that exposing alveolar epithelium to supranormal oxygen concentration causes free radical formation (1). Clinically, hyperoxia (defined as a PaO2 value greater than the normal range for a patient’s age when breathing air [2]) can lead to absorption atelectasis, central nervous system toxicity, reduced cardiac output, and systemic vasoconstriction, all of which could compound critical illness. To mitigate this, the safety of conservative oxygen therapy has been investigated in critically ill patients, and several studies have demonstrated noninferiority of conservative oxygen therapy (3–5), whereas a meta-analysis found that this strategy conferred a mortality benefit (6). The following recent articles (Table 1) assess the effect of conservative versus liberal oxygen treatment on patient outcomes in the critical care environment. The importance of this literature is emphasized by ongoing challenges associated with an expanding number of critically ill patients and increased demand on healthcare resources, in particular oxygen reserves.
AU  - Watson,N
AU  - Brown,E
AU  - Ritchie,AI
AU  - Soni,S
DO  - 10.1164/rccm.202107-1609rr
EP  - 1473
PY  - 2022///
SN  - 1073-449X
SP  - 1470
TI  - Recommended reading from the Imperial College, London fellows
T2  - American Journal of Respiratory and Critical Care Medicine
UR  - http://dx.doi.org/10.1164/rccm.202107-1609rr
UR  - https://www.atsjournals.org/doi/10.1164/rccm.202107-1609RR
UR  - http://hdl.handle.net/10044/1/96734
VL  - 205
ER  -
Download