Imperial College London
Alternate

ProfessorSimonTaylor-Robinson

Faculty of Engineering, Department of Electrical and Electronic Engineering

Visiting Professor
 
 
 
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Contact

 

s.taylor-robinson

 
 
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Location

 

Electrical EngineeringSouth Kensington Campus

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Summary

 

Publications

Citation

BibTex format

@article{Pereira:2022:10.2147/IJGM.S364954,
author = {Pereira, C and Dani, M and Taylor-Robinson, S and Fertleman, M},
doi = {10.2147/IJGM.S364954},
journal = {International Journal of General Medicine},
pages = {5349--5360},
title = {Putative involvement of cytokine modulation in the development of peri-operative neurocognitive disorders},
url = {http://dx.doi.org/10.2147/IJGM.S364954},
volume = {15},
year = {2022}
}
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RIS format (EndNote, RefMan)

TY  - JOUR
AB  - Following surgery, local cytokine-driven inflammation occurs, as part of the normal healing process. Cytokines in thecentral nervous system such as IL-6 and IL-8 may also be elevated. These cytokine changes likely contribute to neuroinflammation,but the complex mechanisms through which this occurs are incompletely understood. It may be that perioperative changes in pro- andanti-inflammatory cytokines have a role in the development of perioperative neurocognitive disorders (PND), such as post-operativedelirium (POD). This review considers the current evidence regarding perioperative cytokine changes in the blood and cerebrospinalfluid (CSF), as well as considering the potential for cytokine-altering therapies to prevent and treat PND.
AU  - Pereira,C
AU  - Dani,M
AU  - Taylor-Robinson,S
AU  - Fertleman,M
DO  - 10.2147/IJGM.S364954
EP  - 5360
PY  - 2022///
SN  - 1178-7074
SP  - 5349
TI  - Putative involvement of cytokine modulation in the development of peri-operative neurocognitive disorders
T2  - International Journal of General Medicine
UR  - http://dx.doi.org/10.2147/IJGM.S364954
UR  - http://hdl.handle.net/10044/1/97658
VL  - 15
ER  -
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