Imperial College London


Faculty of MedicineDepartment of Brain Sciences

Professor of Perinatal Neuroscience



+44 (0)20 3313 8515s.thayyil




529Hammersmith HouseHammersmith Campus





Sudhin Thayyil is a Professor of Perinatal Neuroscience and the Director of the Centre for Perinatal Neuroscience at Imperial College London.

He completed his PhD at University College London in 2010 under the supervision of Prof Andrew Taylor. He worked as a senior clinical lecturer in neonatal medicine at University College London between 2011 and 2013, before moving to Imperial College London as a Reader in Neonatal Medicine in 2014. He was promoted to a Professor of Perinatal Neuroscience in 2020. He has held an NIHR Clinician Scientist award between 2011 and 2016, and currently holds an NIHR Advanced Research Fellowship. His current grant funding exceeds £15 million, and he leads one of the largest clinical research programs on neonatal encephalopathy in the world and has a team of over 50 researchers in the UK and South Asia.


1998: MD, All India Institute of Medical Sciences, New-Delhi
1999: Membership of Royal College of Paediatrics and Child Health, London
1999: Diploma in Child Health, Royal College of Paediatrics and Child Health
2010: Certificate of Completion of Training – Paediatrics, PMETB, UK
2010: Certificate of Sub-specialty (Grid) Training – Neonatal Medicine, PMETB, UK
2010: Doctor of Philosophy (PhD) (2007 to 2010), University College London
2011: Fellowship of Royal College of Paediatrics and Child Health, London

Selected Publications

Journal Articles

Jenkins DD, Moss HG, Brown TR, et al., 2021, Nac and vitamin d improve cns and plasma oxidative stress in neonatal hie and are associated with favorable long-term outcomes, Antioxidants, Vol:10, ISSN:2076-3921, Pages:1-21

Thayyil S, Pant S, Montaldo P, et al., 2021, Hypothermia for moderate or severe neonatal encephalopathy in low and middle-income countries (HELIX): a randomised control trial in India, Sri Lanka and Bangladesh, The Lancet Global Health, Vol:9, ISSN:2214-109X, Pages:e1273-e1285

Pant S, 2021, Parental and professional perceptions of informed consent and participation in a time-critical neonatal trial in Low and Middle-income countries: A mixed methods study, Bmj Global Health, Vol:6, ISSN:2059-7908, Pages:1-9

Montaldo P, Cunnington A, Oliveira V, et al., 2020, Transcriptomic profile of adverse neurodevelopmental outcomes after neonatal encephalopathy, Scientific Reports, Vol:10, ISSN:2045-2322, Pages:1-7

Cartwright JH, Aziz Q, Harmer SC, et al., 2020, Genetic variants in TRPM7 associated with unexplained stillbirth modify ion channel function, Human Molecular Genetics, Vol:29, ISSN:0964-6906, Pages:1797-1807

Oliveira V, von Rosenberg W, Montaldo P, et al., 2019, Early postnatal heart rate variability in healthy newborn infants, Frontiers in Physiology, Vol:10, ISSN:1664-042X, Pages:1-12

Montaldo P, Kaforou M, Pollara G, et al., 2019, Whole blood gene expression reveals specific transcriptome changes in neonatal encephalopathy, Neonatology, Vol:115, ISSN:1661-7800, Pages:68-76

Lally PJ, Montaldo P, Oliveira V, et al., 2019, Magnetic resonance spectroscopy assessment of brain injury after moderate hypothermia in neonatal encephalopathy: a prospective multi-centre study, Lancet Neurology, Vol:18, ISSN:1474-4422, Pages:35-45

Taylor AM, Sebire NJ, Ashworth MT, et al., 2014, Postmortem cardiovascular magnetic resonance imaging in fetuses and children a masked comparison study with conventional autopsy, Circulation, Vol:129, ISSN:0009-7322, Pages:1937-1944

Thayyil S, Sebire NJ, Chitty LS, et al., 2013, Post-mortem MRI versus conventional autopsy in fetuses and children: a prospective validation study, The Lancet, Vol:382, ISSN:0140-6736, Pages:223-233

Thayyil S, Chandrasekaran M, Taylor A, et al., 2010, Cerebral Magnetic Resonance Biomarkers in Neonatal Encephalopathy: A Meta-analysis, Pediatrics, Vol:125, ISSN:0031-4005, Pages:E382-E395

Thayyil S, Cleary JO, Sebire NJ, et al., 2009, Post-mortem examination of human fetuses: a comparison of whole-body high-field MRI at 9.4 T with conventional MRI and invasive autopsy, The Lancet, Vol:374, ISSN:0140-6736, Pages:467-475

Thayyil S, Robertson NJ, Scales A, et al., 2008, Parental consent for research and sudden infant death (vol 372, vol 715, 2008), The Lancet, Vol:372, ISSN:0140-6736, Pages:1222-1222

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