Imperial College London


Faculty of MedicineDepartment of Brain Sciences

Professor of Perinatal Neuroscience



+44 (0)20 3313 8515s.thayyil




529Hammersmith HouseHammersmith Campus





Sudhin Thayyil is a Professor of Perinatal Neuroscience and the Director of the Centre for Perinatal Neuroscience at Imperial College London. He undertook core paediatric training in Leicester and Newcastle, Neonatal grid training in Cambridge-London rotation and PhD at University College London in 2010.

He was appointed as a Senior Clinical Lecturer and Honorary Consultant Neonatologist at University College London in 2011. In 2014, he joined Imperial College London as a Reader and was promoted as a Professor of Perinatal Neuroscience in 2020. He was awarded an NIHR Clinician Scientist fellowship in 2011, and an NIHR advanced fellowship in 2018.

His work is focussed on neonatal encephalopathy – including prevention, disease stratification and neuroprotection both in high income and low and middle-income countries. He is passionate about supporting and mentoring early career researchers, particularly those from disadvantaged backgrounds, and his team members have been awarded several prestigious fellowships in the past five years.


1998: MD, All India Institute of Medical Sciences, New-Delhi
1999: Membership of Royal College of Paediatrics and Child Health, London
1999: Diploma in Child Health, Royal College of Paediatrics and Child Health
2010: Doctor of Philosophy, University College London
2011: Fellowship of Royal College of Paediatrics and Child Health, London

Selected Publications

Journal Articles

Jenkins DD, Moss HG, Brown TR, et al., 2021, Nac and vitamin d improve cns and plasma oxidative stress in neonatal hie and are associated with favorable long-term outcomes, Antioxidants, Vol:10, ISSN:2076-3921, Pages:1-21

Thayyil S, Pant S, Montaldo P, et al., 2021, Hypothermia for moderate or severe neonatal encephalopathy in low and middle-income countries (HELIX): a randomised control trial in India, Sri Lanka and Bangladesh, The Lancet Global Health, Vol:9, ISSN:2214-109X, Pages:e1273-e1285

Pant S, 2021, Parental and professional perceptions of informed consent and participation in a time-critical neonatal trial in Low and Middle-income countries: A mixed methods study, Bmj Global Health, Vol:6, ISSN:2059-7908, Pages:1-9

Montaldo P, Cunnington A, Oliveira V, et al., 2020, Transcriptomic profile of adverse neurodevelopmental outcomes after neonatal encephalopathy, Scientific Reports, Vol:10, ISSN:2045-2322, Pages:1-7

Cartwright JH, Aziz Q, Harmer SC, et al., 2020, Genetic variants in TRPM7 associated with unexplained stillbirth modify ion channel function, Human Molecular Genetics, Vol:29, ISSN:0964-6906, Pages:1797-1807

Oliveira V, von Rosenberg W, Montaldo P, et al., 2019, Early postnatal heart rate variability in healthy newborn infants, Frontiers in Physiology, Vol:10, ISSN:1664-042X, Pages:1-12

Montaldo P, Kaforou M, Pollara G, et al., 2019, Whole blood gene expression reveals specific transcriptome changes in neonatal encephalopathy, Neonatology, Vol:115, ISSN:1661-7800, Pages:68-76

Lally PJ, Montaldo P, Oliveira V, et al., 2019, Magnetic resonance spectroscopy assessment of brain injury after moderate hypothermia in neonatal encephalopathy: a prospective multi-centre study, Lancet Neurology, Vol:18, ISSN:1474-4422, Pages:35-45

Taylor AM, Sebire NJ, Ashworth MT, et al., 2014, Postmortem cardiovascular magnetic resonance imaging in fetuses and children a masked comparison study with conventional autopsy, Circulation, Vol:129, ISSN:0009-7322, Pages:1937-1944

Thayyil S, Sebire NJ, Chitty LS, et al., 2013, Post-mortem MRI versus conventional autopsy in fetuses and children: a prospective validation study, The Lancet, Vol:382, ISSN:0140-6736, Pages:223-233

Thayyil S, Chandrasekaran M, Taylor A, et al., 2010, Cerebral Magnetic Resonance Biomarkers in Neonatal Encephalopathy: A Meta-analysis, Pediatrics, Vol:125, ISSN:0031-4005, Pages:E382-E395

Thayyil S, Cleary JO, Sebire NJ, et al., 2009, Post-mortem examination of human fetuses: a comparison of whole-body high-field MRI at 9.4 T with conventional MRI and invasive autopsy, The Lancet, Vol:374, ISSN:0140-6736, Pages:467-475

Thayyil S, Robertson NJ, Scales A, et al., 2008, Parental consent for research and sudden infant death (vol 372, vol 715, 2008), The Lancet, Vol:372, ISSN:0140-6736, Pages:1222-1222

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