Imperial College London
Alternate

ProfessorSudhinThayyil

Faculty of Medicine, Department of Brain Sciences

Professor of Perinatal Neuroscience
 
 
 
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Contact

 

+44 (0)20 3313 8515s.thayyil

 
 
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Location

 

529Hammersmith HouseHammersmith Campus

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Summary

 

Publications

Citation

BibTex format

@article{Song:2022:10.1007/s00234-021-02821-9,
author = {Song, Y and Lally, PJ and Lopez, MY and Oeltzschner, G and Nebel, MB and Gagoski, B and Kecskemeti, S and Hui, SCN and Zollner, HJ and Shukla, D and Arichi, T and De, Vita E and Yedavalli, V and Thayyil, S and Fallin, D and Dean, DC and Grant, PE and Wisnowski, JL and Edden, RAE},
doi = {10.1007/s00234-021-02821-9},
journal = {Neuroradiology: a journal devoted to neuroimaging and interventional neuroradiology},
pages = {217--232},
title = {Edited magnetic resonance spectroscopy in the neonatal brain},
url = {http://dx.doi.org/10.1007/s00234-021-02821-9},
volume = {64},
year = {2022}
}
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RIS format (EndNote, RefMan)

TY  - JOUR
AB  - J-difference-edited spectroscopy is a valuable approach for the detection of low-concentration metabolites with magnetic resonance spectroscopy (MRS). Currently, few edited MRS studies are performed in neonates due to suboptimal signal-to-noise ratio, relatively long acquisition times, and vulnerability to motion artifacts. Nonetheless, the technique presents an exciting opportunity in pediatric imaging research to study rapid maturational changes of neurotransmitter systems and other metabolic systems in early postnatal life. Studying these metabolic processes is vital to understanding the widespread and rapid structural and functional changes that occur in the first years of life. The overarching goal of this review is to provide an introduction to edited MRS for neonates, including the current state-of-the-art in editing methods and editable metabolites, as well as to review the current literature applying edited MRS to the neonatal brain. Existing challenges and future opportunities, including the lack of age-specific reference data, are also discussed.
AU  - Song,Y
AU  - Lally,PJ
AU  - Lopez,MY
AU  - Oeltzschner,G
AU  - Nebel,MB
AU  - Gagoski,B
AU  - Kecskemeti,S
AU  - Hui,SCN
AU  - Zollner,HJ
AU  - Shukla,D
AU  - Arichi,T
AU  - De,Vita E
AU  - Yedavalli,V
AU  - Thayyil,S
AU  - Fallin,D
AU  - Dean,DC
AU  - Grant,PE
AU  - Wisnowski,JL
AU  - Edden,RAE
DO  - 10.1007/s00234-021-02821-9
EP  - 232
PY  - 2022///
SN  - 0028-3940
SP  - 217
TI  - Edited magnetic resonance spectroscopy in the neonatal brain
T2  - Neuroradiology: a journal devoted to neuroimaging and interventional neuroradiology
UR  - http://dx.doi.org/10.1007/s00234-021-02821-9
UR  - https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000707529100001&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=a2bf6146997ec60c407a63945d4e92bb
UR  - https://link.springer.com/article/10.1007/s00234-021-02821-9
UR  - http://hdl.handle.net/10044/1/110525
VL  - 64
ER  -
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