Imperial College London
Alternate

ProfessorSudhinThayyil

Faculty of Medicine, Department of Brain Sciences

Professor of Perinatal Neuroscience
 
 
 
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Contact

 

+44 (0)20 3313 8515s.thayyil

 
 
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Location

 

529Hammersmith HouseHammersmith Campus

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Summary

 

Publications

Citation

BibTex format

@article{Krishnan:2022:10.1055/a-1905-5334,
author = {Krishnan, V and Kumar, V and Vegda, H and Ujjanappa, V and Manari, A and Vellani, Thamunni A and Thottoli, Puthiyapurayil A and Devadas, S and Fattepur, S and Basett, P and Thayyil, S},
doi = {10.1055/a-1905-5334},
journal = {American Journal of Perinatology: neonatal and maternal-fetal medicine},
title = {Development and validation of a neonatal physical maturity score for low- and middle- income countries.},
url = {http://dx.doi.org/10.1055/a-1905-5334},
year = {2022}
}
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RIS format (EndNote, RefMan)

TY  - JOUR
AB  - Currently available gestational age scoring systems are complex and inaccurate for wider use in low and middle-income countries(LMIC), particularly in infants with neonatal encephalopathy. Here we developed a scoring system based on physical characteristics for identifying late preterm infants from term infants. In the first phase, we examined the accuracy of 10 objective physical characteristics in a prospective cohort of 1006 babies recruited from three hospitals in South India. A weighted scoring system and a photo card were then developed based on the six best performing characteristics, which was validated in another prospective cohort of 1004 babies. The final score had a sensitivity of 66.0%, (95% Confidence intervals (CI), 58.4%-73.8%), specificity of 80.0%, (95% CI, 77.2%-82.7%) and a negative predictive value of 93.0%, (95%CI, 90.5%-94.5%). This scoring system may have wider applications in low and middle-income countries, particularly in community settings and in infants with neonatal encephalopathy.
AU  - Krishnan,V
AU  - Kumar,V
AU  - Vegda,H
AU  - Ujjanappa,V
AU  - Manari,A
AU  - Vellani,Thamunni A
AU  - Thottoli,Puthiyapurayil A
AU  - Devadas,S
AU  - Fattepur,S
AU  - Basett,P
AU  - Thayyil,S
DO  - 10.1055/a-1905-5334
PY  - 2022///
SN  - 0735-1631
TI  - Development and validation of a neonatal physical maturity score for low- and middle- income countries.
T2  - American Journal of Perinatology: neonatal and maternal-fetal medicine
UR  - http://dx.doi.org/10.1055/a-1905-5334
UR  - https://www.ncbi.nlm.nih.gov/pubmed/35858649
UR  - https://www.thieme-connect.de/products/ejournals/abstract/10.1055/a-1905-5334
UR  - http://hdl.handle.net/10044/1/98659
ER  -
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