Imperial College London
Alternate

Dr Sabita Uthaya

Faculty of Medicine, School of Public Health

Professor of Practice (Neonatal Medicine)
 
 
 
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Contact

 

+44 (0)20 3315 7975s.uthaya

 
 
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Location

 

Neonatal UnitChelsea and Westminster HospitalChelsea and Westminster Campus

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Summary

 

Publications

Citation

BibTex format

@article{De:2013:2013/951954,
author = {De, Lucia Rolfe E and Modi, N and Uthaya, S and Hughes, IA and Dunger, DB and Acerini, C and Stolk, RP and Ong, KK},
doi = {2013/951954},
journal = {J Obes},
title = {Ultrasound estimates of visceral and subcutaneous-abdominal adipose tissues in infancy.},
url = {http://dx.doi.org/10.1155/2013/951954},
volume = {2013},
year = {2013}
}
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RIS format (EndNote, RefMan)

TY  - JOUR
AB  - Other imaging techniques to quantify internal-abdominal adiposity (IA-AT) and subcutaneous-abdominal adiposity (SCA-AT) are frequently impractical in infants. The aim of this study was twofold: (a) to validate ultrasound (US) visceral and subcutaneous-abdominal depths in assessing IA-AT and SCA-AT from MRI as the reference method in infants and (b) to analyze the association between US abdominal adiposity and anthropometric measures at ages 3 months and 12 months. Twenty-two infants underwent MRI and US measures of abdominal adiposity. Abdominal US parameters and anthropometric variables were assessed in the Cambridge Baby Growth Study (CBGS), n = 487 infants (23 girls) at age 3 months and n = 495 infants (237 girls) at 12 months. US visceral and subcutaneous-abdominal depths correlated with MRI quantified IA-AT (r = 0.48, P < 0.05) and SCA-AT (r = 0.71, P < 0.001) volumes, respectively. In CBGS, mean US-visceral depths increased by ~20 % between ages 3 and 12 months (P < 0.0001) and at both ages were lower in infants breast-fed at 3 months than in other infants. US-visceral depths at both 3 and 12 months were inversely related to skinfold thickness at birth (P = 0.03 and P = 0.009 at 3 and 12 months, resp.; adjusted for current skinfold thickness). In contrast, US-subcutaneous-abdominal depth at 3 months was positively related to skinfold thickness at birth (P = 0.004). US measures can rank infants with higher or lower IA-AT and SCA-AT. Contrasting patterns of association with visceral and subcutaneous-abdominal adiposities indicate that they may be differentially regulated in infancy.
AU  - De,Lucia Rolfe E
AU  - Modi,N
AU  - Uthaya,S
AU  - Hughes,IA
AU  - Dunger,DB
AU  - Acerini,C
AU  - Stolk,RP
AU  - Ong,KK
DO  - 2013/951954
PY  - 2013///
TI  - Ultrasound estimates of visceral and subcutaneous-abdominal adipose tissues in infancy.
T2  - J Obes
UR  - http://dx.doi.org/10.1155/2013/951954
UR  - https://www.ncbi.nlm.nih.gov/pubmed/23710350
UR  - http://hdl.handle.net/10044/1/50631
VL  - 2013
ER  -
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