Imperial College London


Faculty of MedicineNational Heart & Lung Institute

Research Associate



+44 (0)20 7594 7974s.willis-owen




305Guy Scadding BuildingRoyal Brompton Campus





Saffron Willis-Owen is a bio-statistical data analyst. Her research activities centre around the analysis of highly dimensional, multi-class omic data sets with particular interests in networks, and the molecular underpins of disease co-occurrence and shared features.

Saffron has worked across a broad spectrum of diseases and intermediate traits from muscle endurance to morphine response, as well as various data modalities, including but not limited to, sequence, gene expression, methylation and bacterial abundance. Her current primary area of research activity is lung cancer.

Saffron originally trained at Oxford University, obtaining 1st class honours in Experimental Psychology in 2001, and a D.Phil in 2006 - funded by a Wellcome Trust Prize Studentship exploring the genetic architecture of psychiatric traits. Saffron has spent time with various labs internationally, gaining experience in statistical modelling (Virginia Commonwealth University, USA) and Next Generation Sequence analysis (University of Adelaide, Australia), as well as clinical exposure in the NHS in the field of Clinical Psychology (Cambridge, UK).



Cookson W, Turek E, Moffatt M, et al., 2021, Airway microbial communities, smoking and asthma in a general population sample, Ebiomedicine, Vol:71, ISSN:2352-3964, Pages:1-9

Domingo-Sabugo C, Willis-Owen SAG, Mandal A, et al., 2021, Distinct pancreatic and neuronal Lung Carcinoid molecular subtypes revealed by integrative omic analysis

Willis-Owen S, Domingo Sabugo C, Starren E, et al., 2021, Y disruption, autosomal hypomethylation and poor male lung cancer survival, Scientific Reports, Vol:11, ISSN:2045-2322

Laura G, Liu Y, Fernandes K, et al., 2021, ORMDL3 regulates poly I:C induced inflammatory responses in airway epithelial cells, Bmc Pulmonary Medicine, Vol:21, ISSN:1471-2466

Hoang LT, Domingo-Sabugo C, Starren ES, et al., 2019, Metabolomic, transcriptomic and genetic integrative analysis reveals important roles of adenosine diphosphate in haemostasis and platelet activation in non-small-cell lung cancer, Molecular Oncology, Vol:13, ISSN:1574-7891, Pages:2406-2421

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