DrSophieYacoub

Faculty of Medicine, Department of Infectious Disease

Honorary Clinical Research Fellow

Contact

Location

Commonwealth BuildingHammersmith Campus

Summary

Sophie is a Consultant Physician in Infectious Diseases and General Medicine and is the Dengue Research Group Head at the Oxford University Clinical Research Unit (OUCRU), based in Ho Chi Minh City, Vietnam. She is as an Adjunct Assistant Professor at the Lee Kong Chian School of Medicine in Singapore, and holds an honorary Consultant appointment at London North West University Healthcare NHS Trust in the UK.

She was awarded a PhD in 2016, through the Imperial College Wellcome Trust Clinical PhD Programme and has a Masters degree from the London School of Hygiene and Tropical Medicine. She is a member of the Royal College of Physicians in London. She has clinical academic experience in a variety of tropical diseases, including Chagas disease, malaria and dengue, having worked in northern Australia, Kenya, Tanzania and Honduras. Her work has been supported by grants from the Wellcome Trust, NMRC Singapore, the WHO, British Heart Foundation and the Royal Society of Tropical Medicine.

She currently leads a translational programme of dengue research in OUCRU-Vietnam, including pathogenesis studies, innovative technology for monitoring critically ill patients, physiology studies of severe dengue infections as well as clinical trials of novel therapeutics.

Publications

Journals

Vuong NL, Cheung KW, Periaswamy B, et al.Vuong NL, Cheung KW, Periaswamy B, Vi TT, Duyen HTL, Leong YS, Binte Hamis ZN, Gregorova M, Ooi EE, Sessions O, Rivino L, Yacoub S close, 2022, Hyperinflammatory Syndrome, Natural Killer Cell Function, and Genetic Polymorphisms in the Pathogenesis of Severe Dengue., J Infect Dis, Vol:226, Pages:1338-1347

Choisy M, McBride A, Chambers M, et al.Choisy M, McBride A, Chambers M, Ho Quang C, Nguyen Quang H, Xuan Chau NT, Thi GN, Bonell A, Evans M, Ming D, Ngo-Duc T, Quang Thai P, Dang Giang DH, Dan Thanh HN, Ngoc Nhung H, Lowe R, Maude R, Elyazar I, Surendra H, Ashley EA, Thwaites L, van Doorn HR, Kestelyn E, Dondorp AM, Thwaites G, Vinh Chau NV, Yacoub S close, 2022, Climate change and health in Southeast Asia – defining research priorities and the role of the Wellcome Trust Africa Asia Programmes, Wellcome Open Research, Vol:6, Pages:278-278

Ming DK, Hernandez B, Sangkaew S, et al.Ming DK, Hernandez B, Sangkaew S, Vuong NL, Lam PK, Nguyet NM, Tam DTH, Trung DT, Tien NTH, Tuan NM, Chau NVV, Tam CT, Chanh HQ, Trieu HT, Simmons CP, Wills B, Georgiou P, Holmes AH, Yacoub S close, 2022, Applied machine learning for the risk-stratification and clinical decision support of hospitalised patients with dengue in Vietnam, Plos Digital Health, Vol:1, Pages:e0000005-e0000005

Kerdegari H, Phung NTH, McBride A, et al.Kerdegari H, Phung NTH, McBride A, Pisani L, Nguyen HV, Duong TB, Razavi R, Thwaites L, Yacoub S, Gomez A close, 2021, B-Line Detection and Localization in Lung Ultrasound Videos Using Spatiotemporal Attention, Applied Sciences-basel, Vol:11

Choisy M, McBride A, Chambers M, et al.Choisy M, McBride A, Chambers M, Ho Quang C, Nguyen Quang H, Xuan Chau NT, Thi GN, Bonell A, Evans M, Ming D, Ngo-Duc T, Quang Thai P, Dang Giang DH, Dan Thanh HN, Ngoc Nhung H, Lowe R, Maude R, Elyazar I, Surendra H, Ashley EA, Thwaites L, van Doorn HR, Kestelyn E, Dondorp AM, Thwaites G, Vinh Chau NV, Yacoub S close, 2021, Climate change and health in Southeast Asia – defining research priorities and the role of the Wellcome Trust Africa Asia Programmes, Wellcome Open Research, Vol:6, Pages:278-278

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