Imperial College London


Faculty of MedicineDepartment of Infectious Disease

Honorary Clinical Research Fellow







Commonwealth BuildingHammersmith Campus





Sophie is a Consultant Physician in Infectious Diseases and General Medicine and is the Dengue Research Group Head at the Oxford University Clinical Research Unit (OUCRU), based in Ho Chi Minh City, Vietnam. She is as an Adjunct Assistant Professor at the Lee Kong Chian School of Medicine in Singapore, and holds an honorary Consultant appointment at London North West University Healthcare NHS Trust in the UK.

She was awarded a PhD in 2016, through the Imperial College Wellcome Trust Clinical PhD Programme and has a Masters degree from the London School of Hygiene and Tropical Medicine. She is a member of the Royal College of Physicians in London. She has clinical academic experience in a variety of tropical diseases, including Chagas disease, malaria and dengue, having worked in northern Australia, Kenya, Tanzania and Honduras. Her work has been supported by grants from the Wellcome Trust, NMRC Singapore, the WHO, British Heart Foundation and the Royal Society of Tropical Medicine.

She currently leads a translational programme of dengue research in OUCRU-Vietnam, including pathogenesis studies, innovative technology for monitoring critically ill patients, physiology studies of severe dengue infections as well as clinical trials of novel therapeutics.




McBride A, Mehta P, Rivino L, et al., 2021, Targeting hyperinflammation in infection: can we harness the COVID-19 therapeutics momentum to end the dengue drugs drought? Comment, Lancet Microbe, Vol:2, ISSN:2666-5247, Pages:E277-E278

Sangkaew S, Ming D, Boonyasiri A, et al., 2021, Risk predictors of progression to severe disease during the febrile phase of dengue: a systematic review and meta-analysis, Lancet Infectious Diseases, Vol:21, ISSN:1473-3099, Pages:1014-1026

ISARIC Clinical Characterisation Group, 2021, COVID-19 symptoms at hospital admission vary with age and sex: results from the ISARIC prospective multinational observational study, Infection: Journal of Infectious Disease, ISSN:0300-8126

Nguyen LV, Phung KL, Ming DKY, et al., 2021, Combination of inflammatory and vascular markers in the febrile phase of dengue is associated with more severe outcomes, Elife, Vol:10, ISSN:2050-084X

Nguyen LV, Nguyen THQ, Nguyen THT, et al., 2021, Higher Plasma Viremia in the Febrile Phase Is Associated With Adverse Dengue Outcomes Irrespective of Infecting Serotype or Host Immune Status: An Analysis of 5642 Vietnamese Cases, Clinical Infectious Diseases, Vol:72, ISSN:1058-4838, Pages:E1074-E1083

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