DrSophieYacoub

Faculty of Medicine, Department of Infectious Disease

Honorary Clinical Research Fellow

Contact

Location

Commonwealth BuildingHammersmith Campus

Summary

Sophie is a Consultant Physician in Infectious Diseases and General Medicine and is the Dengue Research Group Head at the Oxford University Clinical Research Unit (OUCRU), based in Ho Chi Minh City, Vietnam. She is as an Adjunct Assistant Professor at the Lee Kong Chian School of Medicine in Singapore, and holds an honorary Consultant appointment at London North West University Healthcare NHS Trust in the UK.

She was awarded a PhD in 2016, through the Imperial College Wellcome Trust Clinical PhD Programme and has a Masters degree from the London School of Hygiene and Tropical Medicine. She is a member of the Royal College of Physicians in London. She has clinical academic experience in a variety of tropical diseases, including Chagas disease, malaria and dengue, having worked in northern Australia, Kenya, Tanzania and Honduras. Her work has been supported by grants from the Wellcome Trust, NMRC Singapore, the WHO, British Heart Foundation and the Royal Society of Tropical Medicine.

She currently leads a translational programme of dengue research in OUCRU-Vietnam, including pathogenesis studies, innovative technology for monitoring critically ill patients, physiology studies of severe dengue infections as well as clinical trials of novel therapeutics.

Publications

Journals

Karolcik S, Ming D, Yacoub S, et al.Karolcik S, Ming D, Yacoub S, Holmes A, Georgiou P close, 2023, A multi-site, multi-wavelength PPG platform for continuous non-invasive health monitoring in hospital settings, Ieee Transactions on Biomedical Circuits and Systems, Vol:17, ISSN:1932-4545, Pages:349-361

Rosenberger KD, Phung Khanh L, Tobian F, et al.Rosenberger KD, Phung Khanh L, Tobian F, Chanpheaktra N, Kumar V, Lum LCS, Sathar J, Pleités Sandoval E, Marón GM, Laksono IS, Mahendradhata Y, Sarker M, Rahman R, Caprara A, Souza Benevides B, Marques ETA, Magalhaes T, Brasil P, Amaral Calvet G, Tami A, Bethencourt SE, Dong Thi Hoai T, Nguyen Tan Thanh K, Tran Van N, Nguyen Tran N, Do Chau V, Yacoub S, Nguyen Van K, Guzmán MG, Martinez PA, Nguyen Than Ha Q, Simmons CP, Wills BA, Geskus RB, Jaenisch T, International Research Consortium on Dengue Risk Assessment, Management, and Surveillance Investigators close, 2023, Early diagnostic indicators of dengue versus other febrile illnesses in Asia and Latin America (IDAMS study): a multicentre, prospective, observational study., Lancet Glob Health, Vol:11, Pages:e361-e372

Hernandez Perez B, Stiff O, Ming D, et al.Hernandez Perez B, Stiff O, Ming D, Ho Quang C, Vuong Nguyen L, Tuan Nguyen M, Chau Nguyen VV, Nguyet Nguyen M, Huy Nguyen Q, Lam Phung K, Tam Dong Thi H, Trung Dinh T, Trieu Huynh T, Wills B, Cameron Paul S, Holmes A, Yacoub S, Georgiou P close, 2023, Learning meaningful latent space representations for patient risk stratification: model development and validation for dengue and other acute febrile illness, Frontiers in Digital Health, Vol:5, ISSN:2673-253X, Pages:1-16

Ming D, Nguyen QH, An LP, et al.Ming D, Nguyen QH, An LP, Chanh HQ, Tam DTH, Truong NT, Huy VX, Hernandez B, Van Nuil JI, Paton C, Georgiou P, Nguyen NM, Holmes A, Tho PV, Yacoub S close, 2023, Mapping patient pathways and understanding clinical decision-making in dengue management to inform the development of digital health tools, Bmc Medical Informatics and Decision Making, Vol:23, ISSN:1472-6947, Pages:1-9

Thi Hue Kien D, Edenborough K, Da Silva Goncalves D, et al.Thi Hue Kien D, Edenborough K, Da Silva Goncalves D, Thuy Vi T, Casagrande E, Thi Le Duyen H, Thi Long V, Thi Dui L, Thi Tuyet Nhu V, Thi Giang N, Thi Xuan Trang H, Lee E, Donovan-Banfield I, Thi Thuy Van H, Minh Nguyet N, Thanh Phong N, Van Vinh Chau N, Wills B, Yacoub S, Flores H, Simmons C close, 2023, Genome evolution of dengue virus serotype 1 under selection by Wolbachia pipientis in Aedes aegypti mosquitoes, Virus Evolution, Vol:9

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