Dr Sara Bonvini

Faculty of Medicine, National Heart & Lung Institute

Academic Visitor

Contact

Location

102Sir Alexander Fleming BuildingSouth Kensington Campus

Summary

Dr. Sara Bonvini is Research Associate in the Respiratory Pharmacology group within the National Heart and Lung Institute.

Sara completed her PhD in 2016 where she is investigated the role of the ion channel TRPV4 in airway sensory nerves. Activation of airway sensory nerves in the lungs can cause reflex events such as cough and bronchoconstriction, both of which are characteristic symptoms of respiratory disease. New and effective therapies to combat these debilitating symptoms are urgently needed.

Her current research involves investigating mechanisms of enhanced reflex responses in airway disease with the aim of developing novel therapies

During her time within the Respiratory Pharmacology laboratory, Sara has been a recipient of a number of prizes including NHLI Day best poster presentation (2013) and best oral presentation (2014), the BALR Young Scientist prize at the summer meeting of 2014, the GSK prize for best oral presentation at the BPS Pharmacology meeting 2014, the best abstract by a Young Investigator in Assembly 5 at the ERS congress 2015 and the Stuart J. Hirst award in 2018.

Publications

Journals

Wortley MA, Bonvini SJ, 2019, TGFβ1 - a novel cause of resistance to bronchodilators in asthma?, American Journal of Respiratory Cell and Molecular Biology, Vol:61, ISSN:1044-1549

Schleich F, Bikov A, Mathioudakis AG, et al.Schleich F, Bikov A, Mathioudakis AG, McDonnell M, Andersson C, Bonini M, Uller L, Idzko M, Singh D, Lopez-Campos JL, Bossios A, Adcock IM, Usmani O, Spanevello A, Bonvini SJ close, 2019, Research highlights from the 2018 European Respiratory Society International Congress: airway disease., Erj Open Research, Vol:5, ISSN:2312-0541

Andersson C, Bonvini SJ, Horvath P, et al.Andersson C, Bonvini SJ, Horvath P, Marquez E, Satia I, Kirkham P, Schleich F, Idzko M, Gosens R, Lopez-Campos JL, Bossios A, Usmani O, Spanevello A, Adcock IM, Mathioudakis AG close, 2018, Research highlights from the 2017 ERS International Congress: airway diseases in focus, Erj Open Research, Vol:4, ISSN:2312-0541

Wortley MA, Adcock JJ, Dubuis ED, et al.Wortley MA, Adcock JJ, Dubuis ED, Maher SA, Bonvini SJ, Delescluse I, Kinloch R, McMurray G, Perros-Huguet C, Papakosta M, Birrell MA, Belvisi MG close, 2017, Targeting fatty acid amide hydrolase as a therapeutic strategy for antitussive therapy, European Respiratory Journal, Vol:50, ISSN:0903-1936, Pages:1-11

Bonvini SJ, Belvisi MG, 2017, Cough and airway disease: the role of ion channels, Pulmonary Pharmacology and Therapeutics, Vol:47, ISSN:1094-5539, Pages:21-28

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