Summary
Sasha Smith is a PhD candidate and Clinical Trial Manager based within the Section of Vascular Surgery, Department of Surgery and Cancer.
She completed a Neuroscience BSc at King's College London and has since worked at University College London and Imperial College London, conducting clinical research in the fields of vascular surgery, neurology and oncology. In her current role as a Clinical Trial Manager, she assists in all aspects of the conduct of clinical trials from conception and initial design through to successful delivery and dissemination of results. She has been a co-applicant on several grant applications for large, multi-center clinical trials, which have successfully resulted in >£6 million in funding in the last three years.
Sasha's PhD is centred on neuromuscular electrical stimulation (NMES) as a novel treatment for people with diabetic neuropathy, and she is currently conducting a multi-center randomised controlled trial (NMES-DN) to investigate its effects. She also leads the DEveloping a Core Outcome Set for Diabetic nEuropathy Clinical Trials (DECODE) project under the supervision of Professor Alun Davies.
Selected Publications
Journal Articles
Smith S, Ravikumar R, Carvalho C, et al., 2024, Neuromuscular electrical stimulation for the treatment of diabetic sensorimotor polyneuropathy: A prospective, cohort, proof-of-concept study., Neurophysiol Clin, Vol:54
Burgess L, Babber A, Shalhoub J, et al., 2023, Neuromuscular electrical stimulation for intermittent claudication (NESIC): multicentre, randomised controlled trial, British Journal of Surgery, Vol:110, ISSN:1365-2168, Pages:1785-1792
Laura B, Smith S, Babber A, et al., 2023, Neuromuscular electrical stimulation as an adjunct to standard care in improving walking distances in intermittent claudication patients: the NESIC RCT, Efficacy and Mechanism Evaluation, Vol:10, ISSN:2050-4365, Pages:1-101
Machin M, Peerbux S, Whittley S, et al., 2023, Examining the benefit of graduated compression stockings in the prevention of hospital-associated venous thromboembolism in low-risk surgical patients: a multicentre cluster randomised controlled trial (PETS Trial), Bmj Open, Vol:13, ISSN:2044-6055, Pages:1-7
Normahani P, Burgess L, Norrie J, et al., 2022, Study protocol for a multicentre comparative diagnostic accuracy study of tools to establish the presence and severity of Peripheral Arterial Disease in people with Diabetes Mellitus: the DM PAD study, Bmj Open, Vol:12, ISSN:2044-6055, Pages:1-9
Smith S, Normahani P, Lane T, et al., 2022, Prevention and management strategies for diabetic neuropathy, Life, Vol:12, ISSN:2075-1729, Pages:1185-1185
Smith S, Normahani P, Lane T, et al., 2022, Pathogenesis of distal symmetrical polyneuropathy in diabetes, Life, Vol:12, ISSN:2075-1729, Pages:1-16
Machin M, Smith S, Nandrha S, et al., 2022, Best Endovenous Treatment, Including Stenting, versus Best Nonendovenous Treatment in Chronic Proximal Deep Venous Disease—The BEST Multicenter Randomized Controlled Trial Protocol, Journal of Vascular Surgery: Venous and Lymphatic Disorders, Vol:10, ISSN:2213-333X, Pages:573-573
Normahani P, Mustafa C, Shalhoub J, et al., 2021, A systematic review and meta-analysis of the diagnostic accuracy of point-of-care tests used to establish the presence of peripheral arterial disease in people with diabetes, Journal of Vascular Surgery, Vol:73, ISSN:0741-5214, Pages:1811-1820
Machin M, Younan H-C, Smith S, et al., 2021, Systematic review on the benefit of graduated compression stockings in the prevention of venous thromboembolism in low-risk surgical patients, Phlebology, Vol:36, ISSN:0268-3555, Pages:184-193
Popat R, Warcel D, O’Nions J, et al., 2020, Characterization of response and corneal events with extended follow-up after belantamab mafodotin (GSK2857916) monotherapy for patients with relapsed multiple myeloma: a case series from the first-time-in-human clinical trial, Haematologica - the Hematology Journal, Vol:105, ISSN:0390-6078, Pages:e261-e263
Smith S, Rossdale J, Serry Y, et al., 2018, Multiple dimensions of excessive daytime sleepiness, Journal of Thoracic Disease, Vol:10, ISSN:2072-1439, Pages:S170-S176