Publications
184 results found
Nijjer SS, Sen SS, Petraco R, et al., 2015, Investigation of human coronary haemodynamics in normal and stenosed vessels to develop systems to quantify stenosis significance and predict the functional gain of intervention, Congress of the European-Society-of-Cardiology (ESC), Publisher: OXFORD UNIV PRESS, Pages: 297-298, ISSN: 0195-668X
Cook C, Ahmad Y, Shun-Shin M, et al., 2015, Instantaneous wave-free ratio (iFR) provides the most robust measure of any resting physiological index: the effects of pressure drift and measurement variability on stenosis misclassification, Congress of the European-Society-of-Cardiology (ESC), Publisher: OXFORD UNIV PRESS, Pages: 296-297, ISSN: 0195-668X
Sen S, Davies JER, 2015, Demystifying Complex Coronary Hemodynamics in Patients Undergoing Transcatheter Aortic Valve Replacement Sowing the Seeds for Coronary Physiological Assessment in the Future?, CIRCULATION-CARDIOVASCULAR INTERVENTIONS, Vol: 8, ISSN: 1941-7640
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- Citations: 4
Nijjer S, Sen S, Petraco R, et al., 2015, VIRTUAL PCI WITH IFR-PULLBACK IN COMPLEX CORONARY DISEASE: THE POTENTIAL FOR REDUCING STENT LENGTH, British-Cardiac-Society (BCS) Annual Conference on Hearts and Genes, Publisher: BMJ PUBLISHING GROUP, Pages: A60-A60, ISSN: 1355-6037
Nijjer S, de Waard G, van de Hoef T, et al., 2015, CHANGES IN RESTING MICROVASCULAR RESISTANCE EXPLAIN WHY RESTING FLOW IS PRESERVED DESPITE INCREASING STENOSIS SEVERITY: THE RESULTS OF THE LARGEST INTERNATIONAL COMBINED CORONARY PRESSURE AND FLOW STUDY, British-Cardiac-Society (BCS) Annual Conference on Hearts and Genes, Publisher: BMJ PUBLISHING GROUP, Pages: A59-A60, ISSN: 1355-6037
Nijjer S, Sen S, Davies J, et al., 2015, VIRTUAL-PCI WITH IFR-PULLBACK CAN PLAN CORONARY INTERVENTION IN COMPLEX CORONARY DISEASE WITH A PREDICTION OF FUNCTIONAL GAIN, British-Cardiac-Society (BCS) Annual Conference on Hearts and Genes, Publisher: BMJ PUBLISHING GROUP, Pages: A61-A61, ISSN: 1355-6037
Nijjer SS, Petraco R, van de Hoef TP, et al., 2015, Change in Coronary Blood Flow After Percutaneous Coronary Intervention in Relation to Baseline Lesion Physiology Results of the JUSTIFY-PCI Study, CIRCULATION-CARDIOVASCULAR INTERVENTIONS, Vol: 8, ISSN: 1941-7640
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- Citations: 29
Nijjer SS, Sen S, Petraco R, et al., 2015, Advances in Coronary Physiology, CIRCULATION JOURNAL, Vol: 79, Pages: 1172-1184, ISSN: 1346-9843
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- Citations: 20
Ahmad Y, Sen S, Shun-Shin MJ, et al., 2015, Intra-aortic Balloon Pump Therapy for Acute Myocardial Infarction AMeta-analysis, JAMA INTERNAL MEDICINE, Vol: 175, Pages: 931-939, ISSN: 2168-6106
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- Citations: 96
Nijjer S, De Waard G, Van De Hoef T, et al., 2015, Determination of the Behavior of Coronary Physiology Under Resting Conditions: The Implications for Stenosis Assessment, 20th Cardiovascular Summit on Transcatheter Cardiovascular Therapeutics Asia Pacific (TCTAP), Publisher: ELSEVIER SCIENCE INC, Pages: S56-S57, ISSN: 0735-1097
Cook CM, Petraco R, Sen S, et al., 2015, Accounting for Right Atrial Pressure in the Calculation of Fractional Flow Reserve Significantly Increases the Number of Physiologically Significant Stenoses Suitable for Revascularization, 20th Cardiovascular Summit on Transcatheter Cardiovascular Therapeutics Asia Pacific (TCTAP), Publisher: ELSEVIER SCIENCE INC, Pages: S57-S57, ISSN: 0735-1097
Foin N, Chico JLG, Nakatani S, et al., 2015, Incomplete Stent Apposition Causes High Shear Flow Disturbances and Delay in Neointimal Coverage as a Function of Strut to Wall Detachment Distance: Implications for Stent Optimization, 20th Cardiovascular Summit on Transcatheter Cardiovascular Therapeutics Asia Pacific (TCTAP), Publisher: ELSEVIER SCIENCE INC, Pages: S43-S43, ISSN: 0735-1097
Petraco R, Sen S, Nijjer S, et al., 2015, Development of an ECG-Independent Algorithm for the Calculation of Instantaneous Wave-Free Ratio (iFR): A Step Towards Further Simplification of Physiological Lesion Assessment, 20th Cardiovascular Summit on Transcatheter Cardiovascular Therapeutics Asia Pacific (TCTAP), Publisher: ELSEVIER SCIENCE INC, Pages: S58-S58, ISSN: 0735-1097
Sayan S, Davies J, 2015, Integrating Physiology into the DNA of Coronary Revascularisation - A Historical Perspective, Contemporary Review and Blueprint for the Future of Coronary Physiology., Interv Cardiol, Vol: 10, Pages: 79-84, ISSN: 1756-1477
The clinical and economic benefits of physiologically guided revascularisation have been demonstrated, yet its clinical adoption remains unacceptably low. Recently, new indices of stenosis severity have been introduced that aim to improve adoption by circumventing the limitations of existing indices. The most validated of these new indices is the instantaneous wave-free ratio (iFR). This review will describe the physiological basis of this index, how it avoids the problems of existing indices such as fractional flow reserve (FFR) and the clinical validation studies of iFR to date. We will then describe a novel use of iFR, which has the potential to transform the use of physiology in the catheter lab and finally integrate physiology into the DNA of coronary revascularisation.
de Waard G, Nijjer S, van de Hoef T, et al., 2015, CORONARY PRESSURE AND FLOW RELATIONSHIPS IN HUMANS: PHASIC ANALYSIS OF NORMAL AND PATHOLOGICAL CORONARY ARTERIES AND THE IMPLICATIONS FOR STENOSIS ASSESSMENT, Scientific Session of the American-College-of-Cardiology (ACC), Publisher: ELSEVIER SCIENCE INC, Pages: A1568-A1568, ISSN: 0735-1097
Nijjer SS, Sen S, Petraco R, et al., 2015, The Instantaneous wave-Free Ratio (iFR) pullback: a novel innovation using baseline physiology to optimise coronary angioplasty in tandem lesions, CARDIOVASCULAR REVASCULARIZATION MEDICINE, Vol: 16, Pages: 167-171, ISSN: 1553-8389
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- Citations: 49
Foin N, Lee RD, Torii R, et al., 2014, Impact of stent strut design in metallic stents and biodegradable scaffolds, INTERNATIONAL JOURNAL OF CARDIOLOGY, Vol: 177, Pages: 800-808, ISSN: 0167-5273
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- Citations: 118
Nijjer SS, Sen S, Petraco R, et al., 2014, Pre-Angioplasty Instantaneous Wave-Free Ratio Pullback Provides Virtual Intervention and Predicts Hemodynamic Outcome for Serial Lesions and Diffuse Coronary Artery Disease, JACC-CARDIOVASCULAR INTERVENTIONS, Vol: 7, Pages: 1386-1396, ISSN: 1936-8798
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- Citations: 81
Petraco R, Al-Lamee R, Gotberg M, et al., 2014, Real-time use of instantaneous wave-free ratio: Results of the ADVISE <i>in-practice</i>: An international, multicenter evaluation of instantaneous wave-free ratio in clinical practice, AMERICAN HEART JOURNAL, Vol: 168, Pages: 739-748, ISSN: 0002-8703
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- Citations: 48
Petraco R, Nijjer SS, Sen S, et al., 2014, Instantaneous wave-free ratio (iFR) and fractional flow reserve (FFR) are equally able to identify ischaemia and flow limitation: a pooled analysis of studies against SPECT, HSR, CFR and PET, 26th Annual Symposium on Transcatheter Cardiovascular Therapeutics (TCT), Publisher: ELSEVIER SCIENCE INC, Pages: B92-B92, ISSN: 0735-1097
Echavarria-Pinto M, van de Hoef TP, Nijjer SS, et al., 2014, Influence of subtended myocardial mass on intracoronary physiology indices of stenosis severity and microcirculatory function., 26th Annual Symposium on Transcatheter Cardiovascular Therapeutics (TCT), Publisher: ELSEVIER SCIENCE INC, Pages: B89-B89, ISSN: 0735-1097
Nijjer SS, Sen S, Petraco R, et al., 2014, Pressure Wire Pullback Using the Instantaneous Wave-Free Ratio (iFR) Can Identify Stenoses and Predict the Improvement After Stenting, 26th Annual Symposium on Transcatheter Cardiovascular Therapeutics (TCT), Publisher: ELSEVIER SCIENCE INC, Pages: B89-B90, ISSN: 0735-1097
Foin N, Nakatani S, Bourantas C, et al., 2014, Incomplete Stent Apposition Causes High Shear Flow Disturbances and Delay in Neointimal Coverage as a Function of Strut-to-wall Detachment Distance, 26th Annual Symposium on Transcatheter Cardiovascular Therapeutics (TCT), Publisher: ELSEVIER SCIENCE INC, Pages: B106-B107, ISSN: 0735-1097
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- Citations: 1
Nijjer SS, Sen S, Petraco R, et al., 2014, Does Coronary Physiology or Anatomy Better Predict the Capacity of Stenting to Increase Flow?, 26th Annual Symposium on Transcatheter Cardiovascular Therapeutics (TCT), Publisher: ELSEVIER SCIENCE INC, Pages: B95-B96, ISSN: 0735-1097
Nijjer SS, Sen S, Petraco R, et al., 2014, Combining pressure wire pullback with the instantaneous wave-free ratio permits measurement of the physiological lesion length of stenoses, Annual Meeting of the European-Society-of-Cardiology (ESC), Publisher: OXFORD UNIV PRESS, Pages: 811-811, ISSN: 0195-668X
Foin N, Petraco R, Sen S, et al., 2014, Assessment of lesion functional significance with virtual FFR - are we going with the flow?, EUROINTERVENTION, Vol: 10, Pages: 535-538, ISSN: 1774-024X
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- Citations: 4
Petraco R, van de Hoef TP, Nijjer S, et al., 2014, Baseline Instantaneous Wave-Free Ratio as a Pressure-Only Estimation of Underlying Coronary Flow Reserve Results of the JUSTIFY-CFR Study (Joined Coronary Pressure and Flow Analysis to Determine Diagnostic Characteristics of Basal and Hyperemic Indices of Functional Lesion Severity-Coronary Flow Reserve), CIRCULATION-CARDIOVASCULAR INTERVENTIONS, Vol: 7, Pages: 492-502, ISSN: 1941-7640
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- Citations: 122
Kousera CA, Nijjer S, Torii R, et al., 2014, Patient-Specific Coronary Stenoses Can Be Modeled Using a Combination of OCT and Flow Velocities to Accurately Predict Hyperemic Pressure Gradients, IEEE TRANSACTIONS ON BIOMEDICAL ENGINEERING, Vol: 61, Pages: 1902-1913, ISSN: 0018-9294
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- Citations: 13
van Lavieren MA, van de Hoef T, Da Cunha RP, et al., 2014, BASAL VERSUS HYPEREMIC CONDITIONS FOR PHYSIOLOGICAL STENOSIS SEVERITY ASSESSMENT, JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, Vol: 63, Pages: A1787-A1787, ISSN: 0735-1097
Nijjer SS, van de Hoef T, da Cunha RP, et al., 2014, RESTING CORONARY BLOOD FLOW VELOCITY IS CONSTANT ACROSS ALL STENOSIS SEVERITIES: IMPLICATIONS FOR TANDEM LESION AND PULLBACK ASSESSMENT, JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, Vol: 63, Pages: A1610-A1610, ISSN: 0735-1097
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