Imperial College London


Faculty of MedicineDepartment of Infectious Disease

Honorary Research Fellow



+44 (0)20 7594 3058simon.moore




Sir Alexander Fleming BuildingSouth Kensington Campus





I'm a synthetic biologist interested in natural product biosynthesis. Recently, I have started as a Faculty Research Fellow (Wellcome Trust) supported through the Department of Medicine working on the biosynthesis of antibiotics.

Primarily, I'm working on the use of in vitro enzymology for the study of natural product biosynthesis, using both cell-free protein synthesis and purified enzyme systems.

For a further details, please refer to the following link -




Freemont PS, Moore S, MacDonald J, et al., 2018, Rapid acquisition and model-based analysis of cell-free transcription-translation reactions from non-model bacteria, Proceedings of the National Academy of Sciences, Vol:115, ISSN:0027-8424, Pages:E4340-E4349

Moore SJ, macdonald JT, freemont PS, 2017, Cell-free synthetic biology for in vitro prototype engineering, Biochemical Society Transactions, Vol:45, ISSN:1470-8752, Pages:785-791

Moore SJ, Lai HE, Needham H, et al., 2017, Streptomyces venezuelae TX-TL - a next generation cell-free synthetic biology tool, Biotechnology Journal, Vol:12, ISSN:1860-7314

Moore SJ, Sowa ST, Schuchardt C, et al., 2017, Elucidation of the biosynthesis of the methane catalyst coenzyme F430, Nature, Vol:543, ISSN:0028-0836, Pages:78-82

Moore SJ, lai H-E, Kelwick R, et al., 2016, EcoFlex - a multifunctional MoClo kit for E. coli synthetic biology, Acs Synthetic Biology, Vol:5, ISSN:2161-5063, Pages:1059-1069

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