Imperial College London

DrSmithaMaretvadakethope

Faculty of Natural SciencesDepartment of Life Sciences

Research Associate in Theoretical Systems Biology
 
 
 
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Contact

 

smitha.maretvadakethope12

 
 
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Location

 

Sir Ernst Chain BuildingSouth Kensington Campus

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Summary

 

Summary

I am a postdoc in theoretical systems biology with a passion for curiosity-driven problems in mathematical biology and fluid dynamics. I'm particularly interested in understanding cell dynamics, whether it be active suspensions of swimming microorganisms, organelle dynamics like flagella or cilia, or the internal dynamical systems that govern cell behaviours and gene expression.

I completed all of my higher education at Imperial College London (BSc in Mathematics, MSc in Applied Mathematics, MRes in Fluid Dynamics Across Scales and a PhD in Mathematics). My PhD was on the topic of “Synchronisation and dynamics of model cilia and flagella.” Afterwards, I joined the University of Liverpool as a postdoc studying the effects of shape, shear, and diffusion on microswimmer suspension dynamics and their boundary encounter interactions, captured through stochastic cell modelling and probability density continuum modelling. Now back at Imperial, I am studying synthetic tipping points to reveal the rules of gene critical timers inspired by bacterial cell-autonomous clocks and differentiation transitions in embryonic development. I'm particularly interested in studying how coexisting critical points control timing dynamics in the presence of static, intrinsic, and extrinsic noise.


Publications

Journals

Maretvadakethope S, Hazel AL, Vasiev B, et al., 2023, The interplay between bulk flow and boundary conditions on the distribution of microswimmers in channel flow, Journal of Fluid Mechanics, Vol:976, ISSN:0022-1120

Maretvadakethope S, Hwang Y, Keaveny E, 2022, Synchronized states of hydrodynamically coupled filaments andtheir stability, Physical Review Fluids, Vol:7, ISSN:2469-990X, Pages:1-17

Maretvadakethope S, Keaveny E, Hwang Y, 2019, The instability of gyrotactically-trapped cell layers, Journal of Fluid Mechanics, Vol:868, ISSN:0022-1120

Conference

Maretvadakethope S, Keaveny E, Hwang Y, 2018, Gyrotactic trapping can be hydrodynamically unstable, Pages:39-40

More Publications