Imperial College London


Faculty of MedicineDepartment of Surgery & Cancer

Professor of Critical Care



+44 (0)20 3313 4521stephen.brett Website




Hammersmith House 570Hammersmith HospitalHammersmith Campus





Professor Stephen Brett is head for research for the Directorate of Anaesthetics and Critical Care within Imperial College Healthcare NHS Trust, leading the Centre for Perioperative Medicine and Critical Care Research and Professor of Critical Care at Imperial College.  The Centre is developing a unique agenda of patient focused projects along the entirety of patient journey, be it in surgery or critical illness, and of course resuscitation; these projects range from epidemiology and public health, through clinical trials to evaluation of the impact of surgery on chronic diseases and of course technology evaluation. The Centre supports many Comprehensive Research Network portfolio studies and is supported through this and the Biomedical Research Centre Scheme.

Professor Brett's personal research interests are in understanding and optimizing long term outcomes after critical illness. He is chief investigator for a number of clinical studies both locally and nationally. He recently lead the NICE guidline development group which published the guideline "Rehabilitation after Critical Illness" (

Prof. Brett is President of the Intensive Care Society  and is an Editor of the journal Critical Care. In addition he serves on a number of Department of Health advisory groups, and provides consultancy to industry in the fields of clinical trial design and supervision, and marketing. 



Warner B, Harry A, Wells M, et al., 2023, Escalation to intensive care for the older patient. An exploratory qualitative study of patients aged over 65 years and their next of kin during the COVID-19 pandemic: the ESCALATE study, Age and Ageing, ISSN:0002-0729

Schutzer-Weissmann J, Wojcikiewicz T, Karmali A, et al., 2023, Apnoeic oxygenation in morbid obesity: a randomised controlled trial comparing facemask and high-flow nasal oxygen delivery, British Journal of Anaesthesia, Vol:130, ISSN:0007-0912, Pages:103-110

Antcliffe DB, Burnham KL, Al-Beidh F, et al., 2022, Transcriptomic Signatures in Sepsis and a Differential Response to Steroids. From the VANISH Randomized Trial(vol 199, pg 980 year 2019), American Journal of Respiratory and Critical Care Medicine, Vol:206, ISSN:1073-449X, Pages:1572-1573

Rubulotta F, Brett S, Boulanger C, et al., 2022, Prevalence of skin pressure injury in critical care patients in the UK: results of a single-day point prevalence evaluation in adult critically ill patient, Bmj Open, Vol:12, ISSN:2044-6055

Grailey K, Leon-Villapalos C, Murray E, et al., 2022, Exploring the working environment of Hospital Managers: a mixed methods study investigating stress, stereotypes, psychological safety and individual resilience, Bmc Health Services Research, Vol:22, ISSN:1472-6963

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