Imperial College London
Alternate

ProfessorStephenBrett

Faculty of Medicine, Department of Surgery & Cancer

Professor of Critical Care
 
 
 
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Contact

 

+44 (0)20 3313 4521stephen.brett Website

 
 
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Location

 

Hammersmith House 570Hammersmith HospitalHammersmith Campus

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Summary

 

Publications

Citation

BibTex format

@article{Benger:2020:10.1016/j.resuscitation.2020.09.026,
author = {Benger, JR and Lazaroo, MJ and Clout, M and Voss, S and Black, S and Brett, S and Kirby, K and Nolan, JP and Reeves, BC and Robinson, M and Scott, LJ and Smartt, H and South, A and Taylor, J and Thomas, M and Wordsworth, S and Rogers, CA},
doi = {10.1016/j.resuscitation.2020.09.026},
journal = {Resuscitation},
pages = {74--82},
title = {Randomized trial of the i-gel supraglottic airway device versus tracheal intubation during out of hospital cardiac arrest (AIRWAYS-2): Patient outcomes at three and six months},
url = {http://dx.doi.org/10.1016/j.resuscitation.2020.09.026},
volume = {157},
year = {2020}
}
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RIS format (EndNote, RefMan)

TY  - JOUR
AB  - AimThe AIRWAYS-2 cluster randomised controlled trial compared the i-gel supraglottic airway device (SGA) with tracheal intubation (TI) as the first advanced airway management (AAM) strategy used by Emergency Medical Service clinicians (paramedics) treating adult patients with non-traumatic out-of-hospital cardiac arrest (OHCA). It showed no difference between the two groups in the primary outcome of modified Rankin Scale (mRS) score at 30 days/hospital discharge. This paper reports outcomes to 6 months.MethodsParamedics from four ambulance services in England were randomised 1:1 to use an i-gel SGA (759 paramedics) or TI (764 paramedics) as their initial approach to AAM. Adults who had a non-traumatic OHCA and were attended by a participating paramedic were enrolled automatically under a waiver of consent. Survivors were invited to complete questionnaires at three and six months after OHCA. Outcomes were analysed using regression methods.Results767/9296 (8.3%) enrolled patients survived to 30 days/hospital discharge and 317/767 survivors (41.3%) consented and were followed-up to six months. No significant differences were found between the two treatment groups in the primary outcome measure (mRS score: 3 months: odds ratio (OR) for good recovery (i-gel/TI, OR) 0.89, 95% CI 0.69–1.14; 6 months OR 0.91, 95% CI 0.71–1.16). EQ-5D-5L scores were also similar between groups and sensitivity analyses did not alter the findings.ConclusionThere were no statistically significant differences between the TI and i-gel groups at three and six months. We therefore conclude that the initially reported finding of no significant difference between groups at 30 days/hospital discharge was sustained when the period of follow-up was extended to six months.
AU  - Benger,JR
AU  - Lazaroo,MJ
AU  - Clout,M
AU  - Voss,S
AU  - Black,S
AU  - Brett,S
AU  - Kirby,K
AU  - Nolan,JP
AU  - Reeves,BC
AU  - Robinson,M
AU  - Scott,LJ
AU  - Smartt,H
AU  - South,A
AU  - Taylor,J
AU  - Thomas,M
AU  - Wordsworth,S
AU  - Rogers,CA
DO  - 10.1016/j.resuscitation.2020.09.026
EP  - 82
PY  - 2020///
SN  - 0300-9572
SP  - 74
TI  - Randomized trial of the i-gel supraglottic airway device versus tracheal intubation during out of hospital cardiac arrest (AIRWAYS-2): Patient outcomes at three and six months
T2  - Resuscitation
UR  - http://dx.doi.org/10.1016/j.resuscitation.2020.09.026
UR  - http://hdl.handle.net/10044/1/83889
VL  - 157
ER  -
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