Imperial College London
Alternate

ProfessorStephenBrett

Faculty of Medicine, Department of Surgery & Cancer

Professor of Critical Care
 
 
 
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Contact

 

+44 (0)20 3313 4521stephen.brett Website

 
 
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Location

 

Hammersmith House 570Hammersmith HospitalHammersmith Campus

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Summary

 

Publications

Citation

BibTex format

@article{Huq:2022:10.1111/anae.15680,
author = {Huq, F and manners, E and O'Callaghan, D and Thakuria, L and Weaver, C and Waheed, U and Stümpfle, R and Brett, SJ and Patel, P and Soni, S},
doi = {10.1111/anae.15680},
journal = {Anaesthesia},
pages = {398--404},
title = {Patient outcomes following transfer between intensive care units during the COVID-19 pandemic},
url = {http://dx.doi.org/10.1111/anae.15680},
volume = {77},
year = {2022}
}
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RIS format (EndNote, RefMan)

TY  - JOUR
AB  - Transferring critically ill patients between intensive care units is often required in the UK, particularly during the COVID-19 pandemic. However, there is a paucity of data examining clinical outcomes following transfer of patients with COVID-19 and whether this strategy affects their acute physiology or outcome. We investigated all transfers critically ill patients with COVID-19 between three different hospital intensive care units, between March 2020 and March 2021. We focused on inter-hospital intensive care unit transfers, i.e. those patients transferred between intensive care units from different hospitals and compared this cohort with intra-hospital intensive care unit transfers, i.e. patients moved between different intensive care units within the same hospital. A total of 507 transfers were assessed, of which 137 met the inclusion criteria. Forty-five patients underwent inter-hospital transfers compared with 92 intra-hospital transfers. There was no significant change in median compliance 6 hours pre-transfer, immediately post-transfer and 24 hours post-transfer in patients who underwent either intra-hospital or inter-hospital transfers. For inter-hospital transfers, there was an initial drop in median PaO2/FiO2 ratio: from median (IQR [range]) 25.1 (17.8–33.7 [12.1–78.0]) kPa 6 hours pre-transfer to 19.5 (14.6–28.9 [9.8–52.0]) kPa immediately post-transfer (p<0.05). However, this had resolved at 24 hours post-transfer: 25.4 (16.2–32.9 [9.4–51.9]) kPa. For intra-hospital transfers, there was no significant change in PaO2/FiO2 ratio. We also found no meaningful difference in pH; PaCO2;, base excess; bicarbonate; or norepinephrine requirements. Our data demonstrate that patients with COVID-19 undergoing mechanical ventilation of the lungs may have short-term physiological deterioration when transferred between nearby hospitals but this resolves within 24 hours. This finding is relevant to the UK critical care strategy in
AU  - Huq,F
AU  - manners,E
AU  - O'Callaghan,D
AU  - Thakuria,L
AU  - Weaver,C
AU  - Waheed,U
AU  - Stümpfle,R
AU  - Brett,SJ
AU  - Patel,P
AU  - Soni,S
DO  - 10.1111/anae.15680
EP  - 404
PY  - 2022///
SN  - 0003-2409
SP  - 398
TI  - Patient outcomes following transfer between intensive care units during the COVID-19 pandemic
T2  - Anaesthesia
UR  - http://dx.doi.org/10.1111/anae.15680
UR  - http://hdl.handle.net/10044/1/94023
VL  - 77
ER  -
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