Imperial College London
Mr Steven Wong

MrStevenWong

Faculty of Engineering, Department of Electrical and Electronic Engineering

Research Postgraduate
 
 
 
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Contact

 

steven.wong15

 
 
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Location

 

Electrical EngineeringSouth Kensington Campus

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Summary

 

Publications

Citation

BibTex format

@inproceedings{Wong:2019:10.1109/BIOCAS.2019.8918743,
author = {Wong, S and Ekanayake, J and Liu, Y and Constandinou, T},
doi = {10.1109/BIOCAS.2019.8918743},
pages = {1--4},
publisher = {IEEE},
title = {An impedance probing system for real-time intra-operative brain tumour tissue discrimination},
url = {http://dx.doi.org/10.1109/BIOCAS.2019.8918743},
year = {2019}
}
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RIS format (EndNote, RefMan)

TY  - CPAPER
AB  - The ability to perform realtime diagnostics of tissueintraoperatively can greatly enhance the precision and effective-ness of the underlying surgery, for example, in tumour resection.To  achieve  this  however  would  require  a  miniature  tool  ableto  performin situ, in-vivocharacterisation  for  distinguishingbetween  different  types  of  tissues.  In  this  work,  we  exploredthe  feasibility   and  requirements  of  implementing   a  portableimpedance  characterisation  system  for  brain  tumour  detection.We  proposed  and  implemented  a  novel  system  based  on  PCB-based instrumentation using a square four-electrode microendo-scopic  probe.  The  system  uses  a  digital-to-analogue  converterto  generate  a  multi-tone  sinusoid  waveform,  and  a  floating  bi-directional voltage-to-current converter to output the differentialstimulation  current  to  one  pair  of  electrodes.  The  other  pairof  electrodes  are  connected  to  the  sensing  circuit  based  on  aninstrumentation amplifier. The recorded data is pre-processed bythe  micro-controller  and  then  analysed  on  a  host  computer.  Toevaluate  the  system,  tetrapolar  impedances  have  been  recordedfrom a number of different electrode configurations to sense pre-defined  resistance  values.  The  overall  system  consumes  143 mAcurrent,  achieve  0.1%  linearity  and  15μV  noise  level,  with  amaximum   signal   bandwidth   of   100 kHz.   Initial   experimentalresults  on  tissue  were  carried  out  on  a  piece  of  rib-eye  steak.Electrical  impedance  maps  (EIM)  and  contour  plots  were  thenreconstructed to represent the impedance value in different tissue region.
AU  - Wong,S
AU  - Ekanayake,J
AU  - Liu,Y
AU  - Constandinou,T
DO  - 10.1109/BIOCAS.2019.8918743
EP  - 4
PB  - IEEE
PY  - 2019///
SP  - 1
TI  - An impedance probing system for real-time intra-operative brain tumour tissue discrimination
UR  - http://dx.doi.org/10.1109/BIOCAS.2019.8918743
UR  - https://ieeexplore.ieee.org/document/8918743
UR  - http://hdl.handle.net/10044/1/74994
ER  -
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