ProfessorStuartCook

Faculty of Medicine, Institute of Clinical Sciences

Visiting Professor

Contact

+44 (0)20 3313 1346stuart.cook

Location

RF 16Sydney StreetRoyal Brompton Campus

Summary

Professor Stuart Cook is the head of the Cardiovascular Genetics and Genomics group within Genetics & Imaging at the National Heart and Lung Institute (NHLI).

Publications

Journals

Adami E, Viswanathan S, Widjaja AA, et al.Adami E, Viswanathan S, Widjaja AA, Ng B, Chothani S, Zhihao N, Tan J, Lio PM, George BL, Altunoglu U, Ghosh K, Paleja BS, Schafer S, Reversade B, Albani S, Ling ALH, O'Reilly S, Cook SA close, 2021, IL11 is elevated in systemic sclerosis and IL11-dependent ERK signalling underlies TGFβ-mediated activation of dermal fibroblasts., Rheumatology (oxford), Vol:60, Pages:5820-5826

Aguib Y, Allouba M, Walsh R, et al.Aguib Y, Allouba M, Walsh R, Ibrahim AM, Halawa S, Afify A, Hosny M, Theotokis PI, Galal A, Elshorbagy S, Roshdy M, Kassem HS, Ellithy A, Buchan R, Whiffin N, Anwer S, Cook S, Moustafa A, ElGuindy A, Ware J, Barton P, Yacoub M close, 2021, New variant with a previously unrecognized mechanism of pathogenicity in hypertrophic cardiomyopathy, Circulation, Vol:144, ISSN:0009-7322, Pages:754-757

Patel PN, Ito K, Willcox JAL, et al.Patel PN, Ito K, Willcox JAL, Haghighi A, Jang MY, Gorham JM, DePalma SR, Lam L, McDonough B, Johnson R, Lakdawala NK, Roberts A, Barton PJR, Cook SA, Fatkin D, Seidman CE, Seidman JG close, 2021, Contribution of noncanonical splice variants to TTN truncating variants cardiomyopathy, Circulation: Genomic and Precision Medicine, Vol:14, ISSN:2574-8300, Pages:1-10

Dong J, Viswanathan S, Adami E, et al.Dong J, Viswanathan S, Adami E, Schafer S, Kuthubudeen FF, Widjaja AA, Cook SA close, 2021, The pro-regenerative effects of hyperIL6 in drug-induced liver injury are unexpectedly due to competitive inhibition of IL11 signaling, Elife, Vol:10, ISSN:2050-084X

Widjaja AA, Dong J, Adami E, et al.Widjaja AA, Dong J, Adami E, Viswanathan S, Ng B, Pakkiri LS, Chothani SP, Singh BK, Lim WW, Zhou J, Shekeran SG, Tan J, Lim SY, Goh J, Wang M, Holgate R, Hearn A, Felkin LE, Yen PM, Dear JW, Drum CL, Schafer S, Cook SA close, 2021, Redefining IL11 as a regeneration-limiting hepatotoxin and therapeutic target in acetaminophen-induced liver injury, Science Translational Medicine, Vol:13, ISSN:1946-6234

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