Imperial College London
Alternate

ProfessorTimBarraclough

Faculty of Natural Sciences, Department of Life Sciences (Silwood Park)

Visiting Professor
 
 
 
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Contact

 

+44 (0)20 7594 2247t.barraclough Website

 
 
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Location

 

N2.4Silwood ParkSilwood Park

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Summary

 

Publications

Citation

BibTex format

@article{Nowell:2021:10.7554/eLife.63194,
author = {Nowell, RW and Wilson, CG and Almeida, P and Schiffer, PH and Fontaneto, D and Becks, L and Rodriguez, F and Arkhipova, IR and Barraclough, TG},
doi = {10.7554/eLife.63194},
journal = {eLife},
pages = {1--37},
title = {Evolutionary dynamics of transposable elements in bdelloid rotifers},
url = {http://dx.doi.org/10.7554/eLife.63194},
volume = {10},
year = {2021}
}
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RIS format (EndNote, RefMan)

TY  - JOUR
AB  - Transposable elements (TEs) are selfish genomic parasites whose ability to spread autonomously is facilitated by sexual reproduction in their hosts. If hosts become obligately asexual, TE frequencies and dynamics are predicted to change dramatically, but the long-term outcome is unclear. Here, we test current theory using whole-genome sequence data from eight species of bdelloid rotifers, a class of invertebrates in which males are thus far unknown. Contrary to expectations, we find a variety of active TEs in bdelloid genomes, at an overall frequency within the range seen in sexual species. We find no evidence that TEs are spread by cryptic recombination or restrained by unusual DNA repair mechanisms. Instead, we find that that TE content evolves relatively slowly in bdelloids and that gene families involved in RNAi-mediated TE suppression have undergone significant expansion, which might mitigate the deleterious effects of active TEs and compensate for the consequences of long-term asexuality.
AU  - Nowell,RW
AU  - Wilson,CG
AU  - Almeida,P
AU  - Schiffer,PH
AU  - Fontaneto,D
AU  - Becks,L
AU  - Rodriguez,F
AU  - Arkhipova,IR
AU  - Barraclough,TG
DO  - 10.7554/eLife.63194
EP  - 37
PY  - 2021///
SN  - 2050-084X
SP  - 1
TI  - Evolutionary dynamics of transposable elements in bdelloid rotifers
T2  - eLife
UR  - http://dx.doi.org/10.7554/eLife.63194
UR  - http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000627596900001&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=1ba7043ffcc86c417c072aa74d649202
UR  - https://elifesciences.org/articles/63194
UR  - http://hdl.handle.net/10044/1/91699
VL  - 10
ER  -
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