Imperial College London
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ProfessorTaraBarwick

Faculty of Medicine, Department of Surgery & Cancer

Professor of Practice (Cancer Imaging)
 
 
 
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Contact

 

t.barwick

 
 
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Location

 

Commonwealth BuildingHammersmith Campus

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Summary

 

Publications

Citation

BibTex format

@article{Connor:2021:10.1016/j.euf.2020.12.002,
author = {Connor, M and Dubash, S and Bass, E and Tam, H and Barwick, T and Vincent, K and Winkler, M and Ahmed, H},
doi = {10.1016/j.euf.2020.12.002},
journal = {European Urology Focus},
pages = {951--954},
title = {Clinical translation of positive metastases identified on prostate-specific membrane antigen positron emission tomography/computed tomography imaging in the management of de novo synchronous oligometastatic prostate cancer},
url = {http://dx.doi.org/10.1016/j.euf.2020.12.002},
volume = {7},
year = {2021}
}
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RIS format (EndNote, RefMan)

TY  - JOUR
AB  - Recent randomised evidence supports the diagnostic superiority of prostate-specific membrane antigen (PSMA) PET/CT, over conventional imaging, in the detection of distant occult metastasis in men with newly diagnosed high-risk prostate cancer. This may result in a rise in the detection of de novo synchronous hormone-sensitive “oligometastatic” prostate cancer. We outline the evidence supporting PSMA PET/CT imaging in primary staging. We also discuss the translation of positive areas, with a high probability of distant metastasis, into clinical therapeutic targets for metastasis-directed interventions. Finally, we highlight the role of PSMA PET/CT as an imaging biomarker. This may have future utility in disease monitoring and prediction of response to systemic, local cytoreductive and metastasis-directed interventions. Patient Summary:  A new whole-body scan can accurately detect cancer deposits, in men in whom distant prostate cancer spread is suspected. This may be useful to monitor and predict response to drug therapy, treatments to the prostate and cancer deposits.
AU  - Connor,M
AU  - Dubash,S
AU  - Bass,E
AU  - Tam,H
AU  - Barwick,T
AU  - Vincent,K
AU  - Winkler,M
AU  - Ahmed,H
DO  - 10.1016/j.euf.2020.12.002
EP  - 954
PY  - 2021///
SN  - 2405-4569
SP  - 951
TI  - Clinical translation of positive metastases identified on prostate-specific membrane antigen positron emission tomography/computed tomography imaging in the management of de novo synchronous oligometastatic prostate cancer
T2  - European Urology Focus
UR  - http://dx.doi.org/10.1016/j.euf.2020.12.002
UR  - http://hdl.handle.net/10044/1/85436
VL  - 7
ER  -
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