Imperial College London

Dr. Tobias Buchborn, Dipl. Psych.

Faculty of MedicineDepartment of Brain Sciences

Honorary Research Fellow



+44 (0)20 7594 3205t.buchborn




Burlington DanesHammersmith Campus





  • Tobias Buchborn graduated in Psychology (Dipl. Psych.) at the Otto-von-Guericke University (OvGU) in Magdeburg, Germany. In his Diploma thesis, he investigated the behavioural and pharmacodynamic effects of the psychedelic 5-HT1A/2A agonist LSD in animal model of depression.
  • Tobias received his PhD (Dr. rer. nat.) in Neurobiology from the Faculty of Natural Sciences, OvGU, based on his research at the Institute of Pharmacology and Toxicology. His PhD project addressed the behavioural and molecular biological correlates of differential tolerance to the psychedelics LSD and DMT, with focus on processes of 5-HT2A regulation.
  • In 2016, Tobias was awarded an MSCA Individual Research Fellowship and started to work at Imperial's Department of Brain Sciences, Laboratory for Neuronal Circuit Dynamics (LNCD). Ever since, his research has been devoted to the corticodynamics of psychedelic drug action.

Online presentation

Breaking convention (2019): Using optogenetics to shine a light on the “psychedelic signature move”
ICPR (2020): Microdosing and tolerance to LSD

Further inormation



Kaertner L, Steinborn M, Kettner H, et al., 2021, Positive expectations predict improved mental-health outcomes linked to psychedelic microdosing, Scientific Reports, Vol:11, ISSN:2045-2322

Buchborn T, Lyons T, Song C, et al., 2020, The serotonin 2A receptor agonist 25CN-NBOH increases murine heart rate and neck-arterial blood flow in a temperature-dependent manner., Journal of Psychopharmacology, Vol:34, ISSN:0269-8811, Pages:786-794

Buchborn T, Lyons T, Knopfel T, 2018, Tolerance and Tachyphylaxis to Head Twitches Induced by the 5-HT2A Agonist 25CN-NBOH in Mice, Frontiers in Pharmacology, Vol:9, ISSN:1663-9812


Buchborn T, Schroeder H, Koch T, et al., 2016, Differential tolerance to lysergic acid diethylamide (LSD) and dimethyltryptamine (DMT) - A matter of serotonin (5-HT) 2A receptor downregulation?, 82nd Annual Meeting of the German-Society-for-Exerimental-and-Clinical-Pharmacology-and-Toxicology (DGPT) / 18th Annual Meeting of the Network-Clinical-Pharmacology-Germany (VKliPha), SPRINGER, Pages:S63-S63, ISSN:0028-1298

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