Imperial College London

DrTimothyEbbels

Faculty of MedicineDepartment of Metabolism, Digestion and Reproduction

Reader in Computational Bioinformatics
 
 
 
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Contact

 

+44 (0)20 7594 3160t.ebbels Website

 
 
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Location

 

131Sir Alexander Fleming BuildingSouth Kensington Campus

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Summary

 

Publications

Citation

BibTex format

@article{Viant:2019:10.1038/s41467-019-10900-y,
author = {Viant, MR and Ebbels, TMD and Beger, RD and Ekman, DR and Epps, DJT and Kamp, H and Leonards, PEG and Loizou, GD and MacRae, JI and van, Ravenzwaay B and Rocca-Serra, P and Salek, RM and Walk, T and Weber, RJM},
doi = {10.1038/s41467-019-10900-y},
journal = {Nature Communications},
title = {Use cases, best practice and reporting standards for metabolomics in regulatory toxicology},
url = {http://dx.doi.org/10.1038/s41467-019-10900-y},
volume = {10},
year = {2019}
}

RIS format (EndNote, RefMan)

TY  - JOUR
AB - Metabolomics is a widely used technology in academic research, yet its application to regulatory science has been limited. The most commonly cited barrier to its translation is lack of performance and reporting standards. The MEtabolomics standaRds Initiative in Toxicology (MERIT) project brings together international experts from multiple sectors to address this need. Here, we identify the most relevant applications for metabolomics in regulatory toxicology and develop best practice guidelines, performance and reporting standards for acquiring and analysing untargeted metabolomics and targeted metabolite data. We recommend that these guidelines are evaluated and implemented for several regulatory use cases.
AU - Viant,MR
AU - Ebbels,TMD
AU - Beger,RD
AU - Ekman,DR
AU - Epps,DJT
AU - Kamp,H
AU - Leonards,PEG
AU - Loizou,GD
AU - MacRae,JI
AU - van,Ravenzwaay B
AU - Rocca-Serra,P
AU - Salek,RM
AU - Walk,T
AU - Weber,RJM
DO - 10.1038/s41467-019-10900-y
PY - 2019///
SN - 2041-1723
TI - Use cases, best practice and reporting standards for metabolomics in regulatory toxicology
T2 - Nature Communications
UR - http://dx.doi.org/10.1038/s41467-019-10900-y
UR - https://www.ncbi.nlm.nih.gov/pubmed/31292445
UR - http://hdl.handle.net/10044/1/71715
VL - 10
ER -